# | Title | Journal | Year | Citations |
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1 | Appion: An integrated, database-driven pipeline to facilitate EM image processing | Journal of Structural Biology | 2009 | 848 |
2 | High-resolution conformation of gramicidin A in a lipid bilayer by solid-state NMR | Science | 1993 | 685 |
3 | The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human Serum | Journal of Biological Chemistry | 1966 | 596 |
4 | Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation | Chemical Reviews | 2018 | 577 |
5 | The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 531 |
6 | Protein-only transmission of three yeast prion strains | Nature | 2004 | 448 |
7 | Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 344 |
8 | Theory of Free Energy and Entropy in Noncovalent Binding | Chemical Reviews | 2009 | 334 |
9 | Influence of structural and morphological factors on the mechanical properties of the polyethylenes | Journal of Polymer Science, Part B: Polymer Physics | 1987 | 315 |
10 | Imaging Membrane Protein Helical Wheels | Journal of Magnetic Resonance | 2000 | 313 |
11 | Protein Allostery and Conformational Dynamics | Chemical Reviews | 2016 | 306 |
12 | Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2 | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 303 |
13 | Random walk in orthogonal space to achieve efficient free-energy simulation of complex systems | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 283 |
14 | Transition state structure of arginine kinase: Implications for catalysis of bimolecular reactions | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 242 |
15 | Influences of Membrane Mimetic Environments on Membrane Protein Structures | Annual Review of Biophysics | 2013 | 237 |
16 | Histidines, heart of the hydrogen ion channel from influenza A virus: Toward an understanding of conductance and proton selectivity | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 236 |
17 | Screening of a library of phage-displayed peptides identifies human Bcl-2 as a taxol-binding protein 1 1Edited by I. A. Wilson | Journal of Molecular Biology | 1999 | 231 |
18 | Structural Organization of the Actin Cytoskeleton at Sites of Clathrin-Mediated Endocytosis | Current Biology | 2011 | 230 |
19 | A continuous spectrophotometric assay for Clostridium histolyticum collagenase | Analytical Biochemistry | 1981 | 228 |
20 | Recreation of the terminal events in physiological integrin activation | Journal of Cell Biology | 2010 | 228 |
21 | Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein | Cell Host and Microbe | 2015 | 223 |
22 | Excited-state intramolecular proton transfer as a fluorescence probe for protein binding-site static polarity. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 221 |
23 | Interplay between excited-state intramolecular proton transfer and charge transfer in flavonols and their use as protein-binding-site fluorescence probes. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 221 |
24 | Structure of the transmembrane region of the M2 protein H+ channel | Protein Science | 2008 | 221 |
25 | Energy Transfer Mechanisms and the Molecular Exciton Model for Molecular Aggregates1, 2 | Radiation Research | 2012 | 216 |
26 | The Mobilization of Iron from the Perfused Mammalian Liver by a Serum Copper Enzyme, Ferroxidase I | Journal of Biological Chemistry | 1971 | 214 |
27 | Structural polymorphism of bacterial adhesion pili | Nature | 1995 | 212 |
28 | Singlet Molecular Oxygen from Superoxide Anion and Sensitized Fluorescence of Organic Molecules | Science | 1970 | 209 |
29 | Phage-display technology – finding a needle in a vast molecular haystack | Current Opinion in Biotechnology | 1999 | 194 |
30 | Accurate marker-free alignment with simultaneous geometry determination and reconstruction of tilt series in electron tomography | Ultramicroscopy | 2006 | 191 |
31 | Influence of solubilizing environments on membrane protein structures | Trends in Biochemical Sciences | 2011 | 186 |
32 | Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus | Biophysical Journal | 2007 | 175 |
33 | Energy transfer to a proton-transfer fluorescence probe: Tryptophan to a flavonol in human serum albumin | Proceedings of the National Academy of Sciences of the United States of America | 1996 | 172 |
34 | Protein folding and binding in confined spaces and in crowded solutions | Journal of Molecular Recognition | 2004 | 171 |
35 | meta-PPISP: a meta web server for protein-protein interaction site prediction | Bioinformatics | 2007 | 162 |
36 | Interaction-site prediction for protein complexes: a critical assessment | Bioinformatics | 2007 | 161 |
37 | Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 159 |
38 | Molecular Basis of Box C/D RNA-Protein Interactions | Structure | 2004 | 158 |
39 | A review on exosomes application in clinical trials: perspective, questions, and challenges | Cell Communication and Signaling | 2022 | 156 |
40 | Crystal Structure and Biochemical Characterization of Human Kallikrein 6 Reveals That a Trypsin-like Kallikrein Is Expressed in the Central Nervous System | Journal of Biological Chemistry | 2002 | 153 |
41 | Tomographic 3D Reconstruction of Quick-Frozen, Ca2+-Activated Contracting Insect Flight Muscle | Cell | 1999 | 152 |
42 | Crystal Structure of a Cbf5-Nop10-Gar1 Complex and Implications in RNA-Guided Pseudouridylation and Dyskeratosis Congenita | Molecular Cell | 2006 | 152 |
43 | 3D reconstruction and processing of volumetric data in cryo-electron tomography | Journal of Structural Biology | 2007 | 150 |
44 | From Induced Fit to Conformational Selection: A Continuum of Binding Mechanism Controlled by the Timescale of Conformational Transitions | Biophysical Journal | 2010 | 148 |
45 | Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment | Proteins: Structure, Function and Bioinformatics | 2016 | 148 |
46 | Intact Flagellar Motor of Borrelia burgdorferi Revealed by Cryo-Electron Tomography: Evidence for Stator Ring Curvature and Rotor/C-Ring Assembly Flexion | Journal of Bacteriology | 2009 | 147 |
47 | Influence of crowded cellular environments on protein folding, binding, and oligomerization: Biological consequences and potentials of atomistic modeling | FEBS Letters | 2013 | 145 |
48 | Loops, Linkages, Rings, Catenanes, Cages, and Crowders: Entropy-Based Strategies for Stabilizing Proteins | Accounts of Chemical Research | 2004 | 144 |
49 | Retrospective on the early development of cryoelectron microscopy of macromolecules and a prospective on opportunities for the future | Journal of Structural Biology | 2008 | 143 |
50 | Age-related changes in rat bone-marrow mesenchymal stem cell plasticity | BMC Cell Biology | 2011 | 141 |