| # | Title | Journal | Year | Citations |
|---|
| 1 | Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis | Nature Medicine | 2002 | 1,558 |
| 2 | A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell–mediated tissue damage | Nature Medicine | 2007 | 1,205 |
| 3 | Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair | Annual Review of Neuroscience | 2001 | 1,146 |
| 4 | The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease | Nature | 2002 | 1,060 |
| 5 | Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation | Perspectives on Psychological Science | 2018 | 900 |
| 6 | Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 755 |
| 7 | Low-Threshold Calcium Currents in Central Nervous System Neurons | Annual Review of Physiology | 1996 | 705 |
| 8 | The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death | Biological Psychiatry | 2000 | 599 |
| 9 | Are subordinates always stressed? a comparative analysis of rank differences in cortisol levels among primates | Hormones and Behavior | 2003 | 599 |
| 10 | Sex modifies the APOE‐related risk of developing Alzheimer disease | Annals of Neurology | 2014 | 592 |
| 11 | Statin therapy and autoimmune disease: from protein prenylation to immunomodulation | Nature Reviews Immunology | 2006 | 581 |
| 12 | CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life | Oncogene | 2005 | 564 |
| 13 | Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain | Nature Neuroscience | 2020 | 558 |
| 14 | Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment | Critical Reviews in Toxicology | 2008 | 536 |
| 15 | Correlated gene expression supports synchronous activity in brain networks | Science | 2015 | 532 |
| 16 | Postnatal maturation of the GABAergic system in rat neocortex | Journal of Neurophysiology | 1991 | 531 |
| 17 | T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis | Nature Medicine | 2010 | 509 |
| 18 | Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration | Neuron | 2006 | 488 |
| 19 | Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine | 2019 | 470 |
| 20 | Understanding the impact of sex and gender in Alzheimer's disease: A call to action | Alzheimer's and Dementia | 2018 | 468 |
| 21 | Protective and therapeutic role for αB-crystallin in autoimmune demyelination | Nature | 2007 | 458 |
| 22 | Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells | Stem Cells | 2012 | 447 |
| 23 | How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis | Annals of Neurology | 2006 | 441 |
| 24 | NGF Signaling in Sensory Neurons | Neuron | 2003 | 437 |
| 25 | Hippocampal Long-Term Potentiation Suppressed by Increased Inhibition in the Ts65Dn Mouse, a Genetic Model of Down Syndrome | Journal of Neuroscience | 2004 | 427 |
| 26 | 1,25-Dihydroxyvitamin D3Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A | Molecular and Cellular Biology | 2011 | 420 |
| 27 | Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500 nm | Nature Communications | 2017 | 416 |
| 28 | Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological features | Journal of Comparative Neurology | 1990 | 414 |
| 29 | Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome | Annals of Neurology | 1999 | 410 |
| 30 | Type II monocytes modulate T cell–mediated central nervous system autoimmune disease | Nature Medicine | 2007 | 407 |
| 31 | Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation | Nature | 1992 | 406 |
| 32 | Antithrombotic and Thrombolytic Therapy for Ischemic Stroke | Chest | 2012 | 401 |
| 33 | Inhibitory role for GABA in autoimmune inflammation | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 395 |
| 34 | Treatment of Autoimmune Neuroinflammation with a Synthetic Tryptophan Metabolite | Science | 2005 | 391 |
| 35 | PRoNTo: Pattern Recognition for Neuroimaging Toolbox | Neuroinformatics | 2013 | 367 |
| 36 | Questions and controversies in the study of time-varying functional connectivity in resting fMRI | Network Neuroscience | 2020 | 364 |
| 37 | Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance | Journal of Neurophysiology | 1992 | 340 |
| 38 | Reciprocal Inhibitory Connections and Network Synchrony in the Mammalian Thalamus | Science | 1999 | 340 |
| 39 | GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas | Nature | 2022 | 339 |
| 40 | A Quarter Century of APOE and Alzheimer’s Disease: Progress to Date and the Path Forward | Neuron | 2019 | 338 |
| 41 | Neural Mechanisms of Sustained Attention Are Rhythmic | Neuron | 2018 | 330 |
| 42 | Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy? | Neuron | 2009 | 327 |
| 43 | Correlation between intrinsic firing patterns and thalamocortical synaptic responses of neurons in mouse barrel cortex | Journal of Neuroscience | 1992 | 320 |
| 44 | The Stressed CNS: When Glucocorticoids Aggravate Inflammation | Neuron | 2009 | 317 |
| 45 | Traumatic Brain Injury Imaging in the Second Near‐Infrared Window with a Molecular Fluorophore | Advanced Materials | 2016 | 311 |
| 46 | Quantifying the local tissue volume and composition in individual brains with magnetic resonance imaging | Nature Medicine | 2013 | 261 |
| 47 | The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation | Experimental Neurology | 2009 | 256 |
| 48 | Design of effective immunotherapy for human autoimmunity | Nature | 2005 | 248 |
| 49 | Seizure diaries for clinical research and practice: Limitations and future prospects | Epilepsy and Behavior | 2012 | 245 |
| 50 | Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis | Nature Biotechnology | 2003 | 242 |
