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Top Articles

#TitleJournalYearCitations
1A matrix metalloproteinase expressed on the surface of invasive tumour cellsNature19942,465
2Surgical Strategy for Spinal MetastasesSpine20011,137
3Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ studyBritish Journal of Cancer2001790
4Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8Nature1993517
5Total En Bloc SpondylectomySpine1997496
6Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cellsCancer Research1999463
7Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.Journal of Biological Chemistry1992454
8Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)Nucleic Acids Research2000413
9Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.Journal of Immunology1992402
10Small hepatocellular carcinoma: treatment with subsegmental transcatheter arterial embolization.Radiology1993399
11mGluR1 in Cerebellar Purkinje Cells Essential for Long-Term Depression, Synapse Elimination, and Motor CoordinationScience2000396
12Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resectionGastroenterology1994384
13Late Radiographic Findings After Anterior Cervical Fusion for Spondylotic MyeloradiculopathySpine1993368
14Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic propertiesJournal of Biological Chemistry1992367
15Collagenase expression in the lungs of transgenic mice causes pulmonary emphysemaCell1992363
16Estrogen activates telomeraseCancer Research1999360
17Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral bloodJournal of Immunology1992351
18Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactionsCytokine and Growth Factor Reviews1998345
19Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF‐induced angiogenesisFASEB Journal2002324
20The landscape of somatic mutations in Down syndrome–related myeloid disordersNature Genetics2013324
21Induction of programmed cell death (apoptosis) by influenza virus infection in tissue culture cellsJournal of General Virology1993323
22Total en bloc spondylectomy for solitary spinal metastasesInternational Orthopaedics1994323
23Involvement of Reactive Oxygen Intermediates in Spontaneous and CD95(Fas/APO-1)–Mediated Apoptosis of NeutrophilsBlood1997317
24Differential expression of bcl-2 and susceptibility to anti-Fas- mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophilsBlood1994314
25Effect of γ-butyrobetaine on fatty liver in juvenile visceral steatosis miceJournal of Pharmacy and Pharmacology2010307
26Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathyKidney International2000305
27Novel Cardiac Precursor-Like Cells from Human Menstrual Blood-Derived Mesenchymal CellsStem Cells2008298
28Quantitative Genetic Variation in CD19 Expression Correlates with AutoimmunityJournal of Immunology2000292
29Hepatocellular carcinoma: correlation of MR imaging and histopathologic findings.Radiology1992267
30Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasisInternational Journal of Cancer1995257
31Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multicenter prospective observational study of 223 patientsJournal of Neurosurgery: Spine2008253
32Matrix Metalloproteinase 7 (Matrilysin) from Human Rectal Carcinoma CellsJournal of Biological Chemistry1995247
33The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A ActivationJournal of Biological Chemistry1995246
34Rapid identification of 11 human intestinalLactobacillusspecies by multiplex PCR assays using group- and species-specific primers derived from the 16S–23S rRNA intergenic spacer region and its flanking 23S rRNAFEMS Microbiology Letters2000243
35Total en bloc spondylectomy for spinal tumors: improvement of the technique and its associated basic backgroundJournal of Orthopaedic Science2006243
36Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomasCancer Research1997243
37Development of Real-time Subcellular Dynamic Multicolor Imaging of Cancer-Cell Trafficking in Live Mice with a Variable-Magnification Whole-Mouse Imaging SystemCancer Research2006242
38Evaluation of immunoreactivity for erbB-2 protein as a marker of poor short term prognosis in gastric cancerCancer Research1991238
39Studies on the Anticancer and Streptolysin S‐Forming Abilities of Hemolytic StreptococciJapanese Journal of Microbiology1967235
40An evaluation of radical resection for pancreatic cancer based on the mode of recurrence as determined by autopsy and diagnostic imagingCancer1993235
41Outcome of ratio of lymph node metastasis in gastric carcinomaAnnals of Surgical Oncology2002229
42Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol.Journal of Clinical Investigation1994226
43Human CYP1B1 Is Regulated by Estradiol via Estrogen ReceptorCancer Research2004226
44Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancerClinical Cancer Research1999224
45Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancyAnnals of the Rheumatic Diseases2012220
46Characterization of side-population cells in human normal endometriumHuman Reproduction2007214
47Expression of human telomerase subunits and correlation with telomerase activity in cervical cancerCancer Research1998214
48Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesisRheumatology2010208
49The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1Proceedings of the National Academy of Sciences of the United States of America1998208
50Collagen remodelling in myocardia of patients with diabetes.Journal of Clinical Pathology1993201