| # | Title | Journal | Year | Citations |
|---|
| 1 | Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles | Physiological Reviews | 2010 | 1,272 |
| 2 | C66 fullerene encaging a scandium dimer | Nature | 2000 | 647 |
| 3 | The SLC3 and SLC7 families of amino acid transporters | Molecular Aspects of Medicine | 2013 | 516 |
| 4 | THE "VESICLE IN A BASKET" | Journal of Cell Biology | 1969 | 438 |
| 5 | Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population | Science Translational Medicine | 2009 | 334 |
| 6 | Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia | American Journal of Human Genetics | 2008 | 317 |
| 7 | Contributions of principal neocortical neurons to magnetoencephalography and electroencephalography signals | Journal of Physiology | 2006 | 315 |
| 8 | A Scandium Carbide Endohedral Metallofullerene: (Sc2C2)@C84 | Angewandte Chemie - International Edition | 2001 | 290 |
| 9 | The SLC1 high-affinity glutamate and neutral amino acid transporter family | Molecular Aspects of Medicine | 2013 | 255 |
| 10 | Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease | BMC Gastroenterology | 2012 | 215 |
| 11 | Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: An in situ hybridization study | Journal of Comparative Neurology | 1996 | 202 |
| 12 | The endocochlear potential depends on two K + diffusion potentials and an electrical barrier in the stria vascularis of the inner ear | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 195 |
| 13 | Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis | Hepatology | 2009 | 194 |
| 14 | Protective mucosal immunity mediated by epithelial CD1d and IL-10 | Nature | 2014 | 172 |
| 15 | Metformin suppresses intestinal polyp growth in ApcMin/+ mice | Cancer Science | 2008 | 166 |
| 16 | Molecular and Physiological Bases of the K+ Circulation in the Mammalian Inner Ear | Physiology | 2006 | 165 |
| 17 | Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition | Gut | 2008 | 160 |
| 18 | A novel PPARγ gene therapy to control inflammation associated with inflammatory bowel disease in a murine model | Gastroenterology | 2003 | 159 |
| 19 | How is the highly positive endocochlear potential formed? The specific architecture of the stria vascularis and the roles of the ion-transport apparatus | Pflugers Archiv European Journal of Physiology | 2010 | 155 |
| 20 | Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells | Journal of Physiology | 2013 | 152 |
| 21 | The collagen-binding protein of Streptococcus mutans is involved in haemorrhagic stroke | Nature Communications | 2011 | 150 |
| 22 | Peroxisome Proliferator-activated Receptor γ-mediated Regulation of Neural Stem Cell Proliferation and Differentiation | Journal of Biological Chemistry | 2006 | 149 |
| 23 | Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters | Endocrinology | 2011 | 146 |
| 24 | Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes | Annals of the Rheumatic Diseases | 2016 | 144 |
| 25 | Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis | Gut | 2011 | 134 |
| 26 | Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model | PLoS Genetics | 2013 | 130 |
| 27 | Serum Ferritin Is Associated With Visceral Fat Area and Subcutaneous Fat Area | Diabetes Care | 2005 | 126 |
| 28 | Leukotriene B 4 and lipoxin A 4 are regulatory signals for neural stem cell proliferation and differentiation | FASEB Journal | 2006 | 124 |
| 29 | Transport of 3-Fluoro-l-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET | Journal of Nuclear Medicine | 2012 | 120 |
| 30 | Expression of glutamate transporters in cultured glial cells | Neuroscience Letters | 1995 | 116 |
| 31 | BCH, an Inhibitor of System L Amino Acid Transporters, Induces Apoptosis in Cancer Cells | Biological and Pharmaceutical Bulletin | 2008 | 115 |
| 32 | Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer | Journal of Pharmacological Sciences | 2007 | 113 |
| 33 | Prostacyclin-Deficient Mice Develop Ischemic Renal Disorders, Including Nephrosclerosis and Renal Infarction | Circulation | 2002 | 109 |
| 34 | Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon | FASEB Journal | 2014 | 109 |
| 35 | Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2 | Cancer Science | 2015 | 109 |
| 36 | High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates | Neuron | 2017 | 108 |
| 37 | Infection of specific strains of Streptococcus mutans, oral bacteria, confers a risk of ulcerative colitis | Scientific Reports | 2012 | 107 |
| 38 | Critical role of aquaporin 3 on growth of human esophageal and oral squamous cell carcinoma | Cancer Science | 2011 | 106 |
| 39 | ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer | British Journal of Cancer | 2014 | 106 |
| 40 | PPARγ ligands inhibit nitrotyrosine formation and inflammatory mediator expressions in adjuvant-induced rheumatoid arthritis mice | European Journal of Pharmacology | 2002 | 105 |
| 41 | Common dysfunctional variants in ABCG2 are a major cause of early-onset gout | Scientific Reports | 2013 | 105 |
| 42 | Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease | Gut | 2008 | 98 |
| 43 | Cultured rat astrocytes possess Na+-Ca2+ exchanger | Glia | 1994 | 97 |
| 44 | Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors | Brain Research | 2007 | 96 |
| 45 | Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth | Obesity | 2015 | 95 |
| 46 | Release of Calcitonin Gene-Related Peptide-Like Immunoreactive Substance from Neuromuscular Junction by Nerve Excitation and Its Action on Striated Muscle | Journal of Neurochemistry | 1990 | 91 |
| 47 | Involvement of Na+-Ca2+Exchanger in Reperfusion-induced Delayed Cell Death of Cultured Rat Astrocytes | European Journal of Neuroscience | 1996 | 86 |
| 48 | Na+-Ca2+ Exchanger: Physiology and Pharmacology. | The Japanese Journal of Pharmacology | 1997 | 86 |
| 49 | Effects of taste stimulation on β-endorphin levels in rat cerebrospinal fluid and plasma | Physiology and Behavior | 2000 | 84 |
| 50 | Life Style-Related Diseases of the Digestive System: Endocrine Disruptors Stimulate Lipid Accumulation in Target Cells Related to Metabolic Syndrome | Journal of Pharmacological Sciences | 2007 | 83 |
