| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 3 | An anatomically comprehensive atlas of the adult human brain transcriptome | Nature | 2012 | 2,321 |
| 4 | Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents | Pediatrics | 2017 | 2,199 |
| 5 | Systematic Reviews: Identifying relevant studies for systematic reviews | BMJ: British Medical Journal | 1994 | 1,918 |
| 6 | Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle | Science | 1993 | 1,850 |
| 7 | Kynurenines in the mammalian brain: when physiology meets pathology | Nature Reviews Neuroscience | 2012 | 1,129 |
| 8 | Molecular biology of microbial ureases | Microbiological Reviews | 1995 | 1,124 |
| 9 | Development of Follicles in the Mammalian Ovary | International Review of Cytology | 1991 | 1,026 |
| 10 | Intraclonal generation of antibody mutants in germinal centres | Nature | 1991 | 1,016 |
| 11 | The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt | Lancet, The | 2000 | 941 |
| 12 | Neural basis of alertness and cognitive performance impairments during sleepiness. I. Effects of 24 h of sleep deprivation on waking human regional brain activity | Journal of Sleep Research | 2000 | 914 |
| 13 | European Federation of Neurological Societies/Peripheral Nerve Society Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society — First Revision | European Journal of Neurology | 2010 | 851 |
| 14 | The Built Environment and Obesity | Epidemiologic Reviews | 2007 | 845 |
| 15 | Editorial: Metal-Enhanced Fluorescence | Journal of Fluorescence | 2002 | 795 |
| 16 | Risk of Mortality Following Clinical Fractures | Osteoporosis International | 2000 | 790 |
| 17 | Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial | Science | 2022 | 788 |
| 18 | Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant | Journal of Translational Medicine | 2020 | 784 |
| 19 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 20 | Regulation of Nrf2—an update | Free Radical Biology and Medicine | 2014 | 735 |
| 21 | Orbitofrontal Cortex as a Cognitive Map of Task Space | Neuron | 2014 | 709 |
| 22 | Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer | Physiological Reviews | 2011 | 706 |
| 23 | Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma | Journal of Experimental Medicine | 2006 | 700 |
| 24 | FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death | Cell | 2003 | 683 |
| 25 | Non-prescription antimicrobial use worldwide: a systematic review | Lancet Infectious Diseases, The | 2011 | 676 |
| 26 | Expert position paper on air pollution and cardiovascular disease | European Heart Journal | 2015 | 646 |
| 27 | Mechanisms of ketamine action as an antidepressant | Molecular Psychiatry | 2018 | 646 |
| 28 | Factors Influencing Publication of Research Results | JAMA - Journal of the American Medical Association | 1992 | 645 |
| 29 | Calcium‐mediated cell injury and cell death | FASEB Journal | 1995 | 587 |
| 30 | A neurophysiological approach to tinnitus: Clinical implications | International Journal of Audiology | 1993 | 570 |
| 31 | Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23 | American Journal of Human Genetics | 2001 | 549 |
| 32 | Requirement of the Inositol Trisphosphate Receptor for Activation of Store-Operated Ca2+ Channels | Science | 2000 | 548 |
| 33 | Bacterial diversity in the oral cavity of 10 healthy individuals | ISME Journal | 2010 | 541 |
| 34 | A critical review of the long-term disability outcomes following hip fracture | BMC Geriatrics | 2016 | 538 |
| 35 | Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease | Lancet, The | 2000 | 523 |
| 36 | CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel | Current Biology | 2006 | 516 |
| 37 | Brain Morphology and Schizophrenia | Archives of General Psychiatry | 1992 | 496 |
| 38 | The Guillain–Barré Syndrome and the 1992–1993 and 1993–1994 Influenza Vaccines | New England Journal of Medicine | 1998 | 489 |
| 39 | Calcium transport and buffering in neurons | Trends in Neurosciences | 1988 | 472 |
| 40 | Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial | Lancet, The | 2010 | 472 |
| 41 | Metabolism of Proline and the Hydroxyprolines | Annual Review of Biochemistry | 1980 | 464 |
| 42 | Genomic insights into the Ixodes scapularis tick vector of Lyme disease | Nature Communications | 2016 | 450 |
| 43 | Local calcium transients triggered by single L-type calcium channel currents in cardiac cells | Science | 1995 | 449 |
| 44 | Kiss1 −/− Mice Exhibit More Variable Hypogonadism than Gpr54−/− Mice | Endocrinology | 2007 | 449 |
| 45 | Pheromonal communication in vertebrates | Nature | 2006 | 414 |
| 46 | Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines | Scandinavian Journal of Gastroenterology | 2006 | 402 |
| 47 | Mechanism of release of calcium from sarcoplasmic reticulum of guinea‐pig cardiac cells. | Journal of Physiology | 1988 | 393 |
| 48 | Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin. | Journal of Biological Chemistry | 1988 | 393 |
| 49 | Dementia as a Risk Factor for Falls and Fall Injuries Among Nursing Home Residents | Journal of the American Geriatrics Society | 2003 | 392 |
| 50 | The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections | Journal of NeuroImmune Pharmacology | 2020 | 391 |
