# | Title | Journal | Year | Citations |
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1 | Dirhodium-catalyzed C-H arene amination using hydroxylamines | Science | 2016 | 224 |
2 | A brief history of antibiotics and select advances in their synthesis | Journal of Antibiotics | 2018 | 121 |
3 | Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation | Nature Communications | 2019 | 83 |
4 | Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins | Journal of the American Chemical Society | 2016 | 78 |
5 | The Role of Organic Synthesis in the Emergence and Development of Antibody–Drug Conjugates as Targeted Cancer Therapies | Angewandte Chemie - International Edition | 2019 | 75 |
6 | Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations | Journal of the American Chemical Society | 2016 | 69 |
7 | Organic synthesis: the art and science of replicating the molecules of living nature and creating others like them in the laboratory | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences | 2014 | 66 |
8 | Rapid heteroatom transfer to arylmetals utilizing multifunctional reagent scaffolds | Nature Chemistry | 2017 | 63 |
9 | Practical Singly and Doubly Electrophilic Aminating Agents: A New, More Sustainable Platform for Carbon–Nitrogen Bond Formation | Journal of the American Chemical Society | 2017 | 60 |
10 | Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents | Journal of the American Chemical Society | 2018 | 45 |
11 | Organocatalytic nitrogen transfer to unactivated olefins via transient oxaziridines | Nature Catalysis | 2020 | 45 |
12 | Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody–Drug Conjugates | Journal of the American Chemical Society | 2018 | 44 |
13 | Hydrogenation of Alkenes via Cooperative Hydrogen Atom Transfer | Journal of the American Chemical Society | 2020 | 44 |
14 | Total Synthesis of Δ12‐Prostaglandin J3, a Highly Potent and Selective Antileukemic Agent | Angewandte Chemie - International Edition | 2014 | 39 |
15 | Total Synthesis and Structural Revision of Antibiotic CJ‐16,264 | Angewandte Chemie - International Edition | 2015 | 39 |
16 | Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7″-epi-C and Full Structural Assignment of Trioxacarcin C | Journal of the American Chemical Society | 2016 | 39 |
17 | Cascade Approach to Highly Functionalized Biaryls by a Nucleophilic Aromatic Substitution with Arylhydroxylamines | Organic Letters | 2019 | 38 |
18 | Total Synthesis and Biological Evaluation of Tiancimycins A and B, Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics | Journal of the American Chemical Society | 2020 | 37 |
19 | Total Synthesis of Myceliothermophins C, D, and E | Angewandte Chemie - International Edition | 2014 | 36 |
20 | 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents | Journal of the American Chemical Society | 2017 | 36 |
21 | Streamlined Total Synthesis of Shishijimicin A and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues thereof and Practical Syntheses of PhthNSSMe and Related Sulfenylating Reagents | Journal of the American Chemical Society | 2018 | 36 |
22 | Synthesis and Biological Evaluation of QRSTUVWXYZA′ Domains of Maitotoxin | Journal of the American Chemical Society | 2014 | 35 |
23 | Total Synthesis in Search of Potent Antibody–Drug Conjugate Payloads. From the Fundamentals to the Translational | Accounts of Chemical Research | 2019 | 34 |
24 | Total Synthesis Endeavors and Their Contributions to Science and Society:A Personal Account | CCS Chemistry | 0 | 34 |
25 | Synthesis and Biological Investigation of Δ12-Prostaglandin J3 (Δ12-PGJ3) Analogues and Related Compounds | Journal of the American Chemical Society | 2016 | 33 |
26 | Total Syntheses of Disorazoles A1 and B1 and Full Structural Elucidation of Disorazole B1 | Journal of the American Chemical Society | 2017 | 33 |
27 | The Emergence and Evolution of Organic Synthesis and Why It is Important to Sustain It as an Advancing Art and Science for Its Own Sake | Israel Journal of Chemistry | 2018 | 33 |
28 | Recent Advances in Small Molecule‐Based Intracellular pH Probes | ChemBioChem | 2022 | 30 |
29 | Total Synthesis of Trioxacarcin DC‐45‐A2 | Angewandte Chemie - International Edition | 2015 | 23 |
30 | Total Synthesis of Δ12‐Prostaglandin J3: Evolution of Synthetic Strategies to a Streamlined Process | Chemistry - A European Journal | 2016 | 22 |
31 | Practical Synthesis of p‐ and o‐Amino‐ and Methoxyphenolic Anthraquinones | Angewandte Chemie - International Edition | 2015 | 20 |
32 | DNA Binding and Cleavage Modes of Shishijimicin A | Journal of the American Chemical Society | 2019 | 20 |
33 | Uncialamycin-based antibody–drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect | Proceedings of the National Academy of Sciences of the United States of America | 2021 | 20 |
34 | The Chemistry-Biology-Medicine Continuum and the Drug Discovery and Development Process in Academia | Chemistry and Biology | 2014 | 19 |
35 | Total Synthesis and Full Structural Assignment of Namenamicin | Journal of the American Chemical Society | 2018 | 18 |
36 | Total Synthesis of the Monomeric Unit of Lomaiviticin A | Journal of the American Chemical Society | 2020 | 18 |
37 | Catalyst: Synthetic Organic Chemistry as a Force for Good | CheM | 2016 | 17 |
38 | Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues | Journal of Organic Chemistry | 2020 | 17 |
39 | A Reverse Approach to the Total Synthesis of Halichondrin B | Journal of the American Chemical Society | 2021 | 16 |
40 | Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling | Beilstein Journal of Organic Chemistry | 2013 | 15 |
41 | Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues | Journal of Organic Chemistry | 2019 | 15 |
42 | Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues | Journal of the American Chemical Society | 2017 | 14 |
43 | Transition metal-free direct dehydrogenative arylation of activated C(sp3)–H bonds: synthetic ambit and DFT reactivity predictions | Chemical Science | 2018 | 14 |
44 | Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues | Journal of the American Chemical Society | 2020 | 14 |
45 | Syntheses of Cyclopropyl Analogues of Disorazoles A1 and B1 and Their Thiazole Counterparts | Journal of Organic Chemistry | 2018 | 13 |
46 | Overview of Amino Acid Modifications by Iron- and α-Ketoglutarate-Dependent Enzymes | ACS Catalysis | 2023 | 12 |
47 | C–H-Functionalization logic guides the synthesis of a carbacyclopamine analog | Beilstein Journal of Organic Chemistry | 2014 | 11 |
48 | Efficient Synthesis of Dimeric Oxazoles, Piperidines and Tetrahydroisoquinolines from N‐Substituted 2‐Oxazolones | Chemistry - A European Journal | 2016 | 11 |
49 | Die Bedeutung der organischen Synthese bei der Entstehung und Entwicklung von Antikörper‐Wirkstoff‐Konjugaten als gezielte Krebstherapien | Angewandte Chemie | 2019 | 11 |
50 | Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody–Drug Conjugates | Journal of the American Chemical Society | 2020 | 11 |