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Top Articles

#TitleJournalYearCitations
1Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1Science20001,199
2Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experienceNature Medicine2005645
3Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissueNature Medicine2005560
4In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell nicheNature2011502
5Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatmentNature Medicine2000491
6Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantationBlood2006410
7Mixed Chimerism and Transplant ToleranceImmunity2001378
8Mixed lymphohaemopoietic chimerism and graft-ver suslymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantationLancet, The1999376
9Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell ToleranceJournal of Experimental Medicine1998328
10Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioningNature Medicine1997297
11Xenotransplantation: current status and a perspective on the futureNature Reviews Immunology2007284
12BRAIN DEATH AND ITS INFLUENCE ON DONOR ORGAN QUALITY AND OUTCOME AFTER TRANSPLANTATION1Transplantation1999280
13Role for CD47-SIRP  signaling in xenograft rejection by macrophagesProceedings of the National Academy of Sciences of the United States of America2007270
14Will the Pig Solve the Transplantation Backlog?Annual Review of Medicine2002267
15Sepsis-Associated Myocardial DysfunctionChest2006267
16No Evidence for Significant Transdifferentiation of Bone Marrow Into Pancreatic  -Cells In VivoDiabetes2004254
17The Chromatin-Modifying Enzyme Ezh2 Is Critical for the Maintenance of Regulatory T Cell Identity after ActivationImmunity2015253
18Induction Of Kidney Allograft Tolerance After Transient Lymphohematopoietic Chimerism In Patients With Multiple Myeloma And End-Stage Renal Disease1Transplantation2002248
19Myeloma Responses and Tolerance Following Combined Kidney and Nonmyeloablative Marrow Transplantation: In Vivo and In Vitro AnalysesAmerican Journal of Transplantation2006247
20Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT MiceJournal of Virology2009247
21Long-Term Results in Recipients of Combined HLA-Mismatched Kidney and Bone Marrow Transplantation Without Maintenance ImmunosuppressionAmerican Journal of Transplantation2014247
22Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen.Journal of Immunology1994244
23Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimenJournal of Immunology1994224
24Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergyBlood2008212
25Human anti-porcine xenogeneic T cell response. Evidence for allelic specificity of mixed leukocyte reaction and for both direct and indirect pathways of recognition.Journal of Immunology1995211
26DISCORDANT ORGAN XENOTRANSPLANTATION IN PRIMATESTransplantation1998208
27Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targetsJournal of Clinical Investigation2000206
28Immunogenicity of umbilical cord tissue–derived cellsBlood2008205
29Contrast nephropathy: Review focusing on preventionJournal of the American College of Cardiology2004204
30Treatment of severe autoimmune disease by stem-cell transplantationNature2005202
31Skin graft tolerance across a discordant xenogeneic barrierNature Medicine1996196
32RNAi-mediated CCR5 Silencing by LFA-1-targeted Nanoparticles Prevents HIV Infection in BLT MiceMolecular Therapy2010192
33Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal modelJournal of Clinical Investigation2000192
34Tolerization of Anti–Galα1-3Gal Natural Antibody–forming B Cells by Induction of Mixed ChimerismJournal of Experimental Medicine1998189
35Human anti-porcine xenogeneic T cell response. Evidence for allelic specificity of mixed leukocyte reaction and for both direct and indirect pathways of recognitionJournal of Immunology1995189
36HIGH-DOSE PORCINE HEMATOPOIETIC CELL TRANSPLANTATION COMBINED WITH CD40 LIGAND BLOCKADE IN BABOONS PREVENTS AN INDUCED ANTI-PIG HUMORAL RESPONSETransplantation2000183
37Mixed chimerism and tolerance without whole body irradiation in a large animal modelJournal of Clinical Investigation2000182
38α1,3-Galactosyltransferase Gene-Knockout Pig Heart Transplantation in Baboons with Survival Approaching 6 MonthsTransplantation2005178
39MODIFICATIONS OF THE CONDITIONING REGIMEN FOR ACHIEVING MIXED CHIMERISM AND DONOR-SPECIFIC TOLERANCE IN CYNOMOLGUS MONKEYS1Transplantation1997176
40THYMIC DEPENDENCE OF LOSS OF TOLERANCE IN MIXED ALLOGENEIC BONE MARROW CHIMERAS AFTER DEPLETION OF DONOR ANTIGENTransplantation1996167
41COAGULATION AND THROMBOTIC DISORDERS ASSOCIATED WITH PIG ORGAN AND HEMATOPOIETIC CELL TRANSPLANTATION IN NONHUMAN PRIMATESTransplantation2000164
42Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12.Journal of Clinical Investigation1998164
43Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimenBiology of Blood and Marrow Transplantation1999161
44Report of the xenotransplantation advisory committee of the international society for heart and lung transplantation:Journal of Heart and Lung Transplantation2000158
45LONG-TERM OUTCOME AND ALLOANTIBODY PRODUCTION IN A NON-MYELOABLATIVE REGIMEN FOR INDUCTION OF RENAL ALLOGRAFT TOLERANCE1Transplantation1999157
46PORCINE KIDNEY AND HEART TRANSPLANTATION IN BABOONS UNDERGOING A TOLERANCE INDUCTION REGIMEN AND ANTIBODY ADSORPTION1Transplantation1999155
47Disordered regulation of coagulation and platelet activation in xenotransplantationXenotransplantation2000154
48Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrowBlood1994153
49INTRATHYMIC DELETION OF ALLOREACTIVE T CELLS IN MIXED BONE MARROW CHIMERAS PREPARED WITH A NONMYELOABLATIVE CONDITIONING REGIMEN1Transplantation1998151
50Xenoantigens and xenoantibodiesXenotransplantation1998147