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#TitleJournalYearCitations
1Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancerScience20156,756
2International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung AdenocarcinomaJournal of Thoracic Oncology20114,127
3Tumour exosome integrins determine organotropic metastasisNature20153,688
4The 2015 World Health Organization Classification of Lung TumorsJournal of Thoracic Oncology20153,313
5Integrative Genomic Profiling of Human Prostate CancerCancer Cell20103,151
6Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase DomainPLoS Medicine20053,022
7Tumor mutational load predicts survival after immunotherapy across multiple cancer typesNature Genetics20192,702
8Genomic analyses identify molecular subtypes of pancreatic cancerNature20162,700
9Integrative Clinical Genomics of Advanced Prostate CancerCell20152,660
10Genes that mediate breast cancer metastasis to lungNature20052,581
11Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patientsNature Medicine20172,473
12Tumour invasion and metastasis initiated by microRNA-10b in breast cancerNature20072,382
13Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networksNature Medicine20012,352
14The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular TumoursEuropean Urology20162,211
15Whole genomes redefine the mutational landscape of pancreatic cancerNature20152,132
16The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014Annals of Oncology20152,122
17Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic LeukemiaScience Translational Medicine20142,069
18Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencingNature Biotechnology20131,785
19The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-HydroxyglutarateCancer Cell20101,754
20CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic LeukemiaScience Translational Medicine20131,748
21Endogenous human microRNAs that suppress breast cancer metastasisNature20081,743
22Comprehensive Molecular Characterization of Muscle-Invasive Bladder CancerCell20171,742
23Comprehensive genomic profiles of small cell lung cancerNature20151,634
24Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancerNature20121,605
25Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel SequencingCell20121,591
26Genes that mediate breast cancer metastasis to the brainNature20091,587
27Organoid Models of Human and Mouse Ductal Pancreatic CancerCell20151,584
28Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)Journal of Molecular Diagnostics20151,566
29MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibProceedings of the National Academy of Sciences of the United States of America20071,557
30REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense VariantsAmerican Journal of Human Genetics20161,555
31Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in miceImmunity19951,545
32DAXX / ATRX , MEN1 , and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine TumorsScience20111,504
33Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinomaNature Genetics20151,491
34Pten is essential for embryonic development and tumour suppressionNature Genetics19981,428
35The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53Cell19981,412
36KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or ErlotinibPLoS Medicine20051,331
37The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder TumoursEuropean Urology20161,323
38Clinical-grade computational pathology using weakly supervised deep learning on whole slide imagesNature Medicine20191,320
39Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and HeartJournal of Thoracic Oncology20151,301
40Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.Journal of Clinical Oncology19961,289
41The AIDS dementia complex: II. NeuropathologyAnnals of Neurology19861,224
42miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasisNature Cell Biology20101,216
43Endothelial Apoptosis as the Primary Lesion Initiating Intestinal Radiation Damage in MiceScience20011,194
44Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid CarcinomaJAMA Oncology20161,192
45Organoid Cultures Derived from Patients with Advanced Prostate CancerCell20141,184
46Phosphorylation and Functional Inactivation of TSC2 by ErkCell20051,132
47STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung AdenocarcinomaCancer Discovery20181,108
48Punctuated Evolution of Prostate Cancer GenomesCell20131,107
49Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancerNature Genetics20121,049
50Immunotherapy in colorectal cancer: rationale, challenges and potentialNature Reviews Gastroenterology and Hepatology20191,039