# | Title | Journal | Year | Citations |
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1 | ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context | BMC Bioinformatics | 2006 | 2,218 |
2 | CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy | Nature | 2019 | 1,528 |
3 | Modes of p53 Regulation | Cell | 2009 | 1,426 |
4 | AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice | Cell Metabolism | 2011 | 1,356 |
5 | Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer | Nature Genetics | 2012 | 1,186 |
6 | Ferroptosis as a target for protection against cardiomyopathy | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 1,174 |
7 | Human CtIP promotes DNA end resection | Nature | 2007 | 1,158 |
8 | Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas | Nature | 2001 | 921 |
9 | Analysis of the coding genome of diffuse large B-cell lymphoma | Nature Genetics | 2011 | 871 |
10 | Essential role of Plzf in maintenance of spermatogonial stem cells | Nature Genetics | 2004 | 852 |
11 | Inactivating mutations of acetyltransferase genes in B-cell lymphoma | Nature | 2011 | 822 |
12 | PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma | Cancer Research | 2005 | 813 |
13 | Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia | Nature Medicine | 2007 | 804 |
14 | Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence | Cell | 2012 | 768 |
15 | Non-coding recurrent mutations in chronic lymphocytic leukaemia | Nature | 2015 | 749 |
16 | An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma | Cell | 2011 | 671 |
17 | Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination | Nature Immunology | 2006 | 647 |
18 | Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones | Molecular and Cellular Proteomics | 2007 | 639 |
19 | Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis | Molecular Cell | 2006 | 635 |
20 | Clonal evolution of glioblastoma under therapy | Nature Genetics | 2016 | 591 |
21 | SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice | Cell Metabolism | 2008 | 588 |
22 | The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells | Nature | 2004 | 576 |
23 | Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation | Journal of Experimental Medicine | 2011 | 565 |
24 | Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas | Nature Genetics | 2014 | 534 |
25 | Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size | Molecular and Cellular Biology | 2005 | 504 |
26 | ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway | Nature Cell Biology | 2019 | 486 |
27 | ARF-BP1/Mule Is a Critical Mediator of the ARF Tumor Suppressor | Cell | 2005 | 484 |
28 | Genetics of Follicular Lymphoma Transformation | Cell Reports | 2014 | 471 |
29 | Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 468 |
30 | Id family of helix-loop-helix proteins in cancer | Nature Reviews Cancer | 2005 | 467 |
31 | Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 445 |
32 | p53 post-translational modification: deregulated in tumorigenesis | Trends in Molecular Medicine | 2010 | 438 |
33 | Negative regulation of the deacetylase SIRT1 by DBC1 | Nature | 2008 | 435 |
34 | The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia | Journal of Experimental Medicine | 2007 | 427 |
35 | γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia | Nature Medicine | 2009 | 417 |
36 | The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry | Nature Immunology | 2012 | 405 |
37 | Gene Expression Profiles During Hepatic Stellate Cell Activation in Culture and In Vivo | Gastroenterology | 2007 | 402 |
38 | Combined Genetic Inactivation of β2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma | Cancer Cell | 2011 | 385 |
39 | An anatomic transcriptional atlas of human glioblastoma | Science | 2018 | 384 |
40 | Acetylation inactivates the transcriptional repressor BCL6 | Nature Genetics | 2002 | 377 |
41 | Germinal centres and B cell lymphomagenesis | Nature Reviews Immunology | 2015 | 375 |
42 | Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis | Nature Medicine | 2015 | 372 |
43 | The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development | Journal of Experimental Medicine | 2012 | 363 |
44 | A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia | Nature Medicine | 2014 | 349 |
45 | Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas | Blood | 2012 | 346 |
46 | Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice | Cancer Cell | 2005 | 342 |
47 | A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex | Nature Chemical Biology | 2008 | 340 |
48 | Roles of BCL6 in normal and transformed germinal center B cells | Immunological Reviews | 2012 | 329 |
49 | Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma | Journal of Experimental Medicine | 2006 | 326 |
50 | Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia | Cancer Cell | 2011 | 322 |