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Top Articles

#TitleJournalYearCitations
1Folding non-homologous proteins by coupling deep-learning contact maps with I-TASSER assembly simulationsCell Reports Methods2021272
2Deep learning neural network tools for proteomicsCell Reports Methods202148
3A mixture-of-experts deep generative model for integrated analysis of single-cell multiomics dataCell Reports Methods202147
4hdWGCNA identifies co-expression networks in high-dimensional transcriptomics dataCell Reports Methods202343
5Super-resolved live-cell imaging using random illumination microscopyCell Reports Methods202136
6PeakVI: A deep generative model for single-cell chromatin accessibility analysisCell Reports Methods202234
7DIPA-CRISPR is a simple and accessible method for insect gene editingCell Reports Methods202234
8A method for characterizing daily physiology from widely used wearablesCell Reports Methods202130
9Global analysis of protein arginine methylationCell Reports Methods202127
10Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membraneCell Reports Methods202227
11Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cellsCell Reports Methods202126
12A size-exclusion-based approach for purifying extracellular vesicles from human plasmaCell Reports Methods202125
13Development of a pan-neuronal genetic driver in Aedes aegypti mosquitoesCell Reports Methods202125
14Model-based assessment of mammalian cell metabolic functionalities using omics dataCell Reports Methods202125
15A molecular toolbox for ADP-ribosyl binding proteinsCell Reports Methods202125
16Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutationsCell Reports Methods202124
17Inference of high-resolution trajectories in single-cell RNA-seq data by using RNA velocityCell Reports Methods202124
18Spectral fiber photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activityCell Reports Methods202223
19Toward reproducible, scalable, and robust data analysis across multiplex tissue imaging platformsCell Reports Methods202122
20Discovery and validation of human genomic safe harbor sites for gene and cell therapiesCell Reports Methods202222
21High-throughput identification of autoantibodies that target the human exoproteomeCell Reports Methods202222
22Single-cell intracellular epitope and transcript detection reveals signal transduction dynamicsCell Reports Methods202121
23Graph embedding and Gaussian mixture variational autoencoder network for end-to-end analysis of single-cell RNA sequencing dataCell Reports Methods202321
24Metatranscriptomics to characterize respiratory virome, microbiome, and host response directly from clinical samplesCell Reports Methods202119
25Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAVCell Reports Methods202219
26An integrated toolbox to profile macrophage immunometabolismCell Reports Methods202218
27A weakly supervised deep learning approach for label-free imaging flow-cytometry-based blood diagnosticsCell Reports Methods202117
28GEM-IL: A highly responsive fluorescent lactate indicatorCell Reports Methods202117
29Stable and reproducible homologous recombination enables CRISPR-based engineering in the fungus Rhizopus microsporusCell Reports Methods202117
30Unlocking SARS-CoV-2 detection in low- and middle-income countriesCell Reports Methods202115
31An optimized genome-wide, virus-free CRISPR screen for mammalian cellsCell Reports Methods202114
32Genetically encoded biosensors for evaluating NAD+/NADH ratio in cytosolic and mitochondrial compartmentsCell Reports Methods202114
33Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidicsCell Reports Methods202214
34Uncovering biomarkers during therapeutic neuromodulation with PARRM: Period-based Artifact Reconstruction and Removal MethodCell Reports Methods202113
35A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinomaCell Reports Methods202113
36Multi-color super-resolution imaging to study human coronavirus RNA during cellular infectionCell Reports Methods202213
37Toward real-world automated antibody design with combinatorial Bayesian optimizationCell Reports Methods202313
38Applications of deep learning in understanding gene regulationCell Reports Methods202313
39Machine learning approaches to predict drug efficacy and toxicity in oncologyCell Reports Methods202313
40High-throughput 5′P sequencing enables the study of degradation-associated ribosome stallsCell Reports Methods202112
41CUBIC-Cloud provides an integrative computational framework toward community-driven whole-mouse-brain mappingCell Reports Methods202112
42Dense optical flow software to quantify cellular contractilityCell Reports Methods202112
43Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometryCell Reports Methods202112
44Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting mutationsCell Reports Methods202212
45An intravitreal implant injection method for sustained drug delivery into mouse eyesCell Reports Methods202112
46Open-source analysis and visualization of segmented vasculature datasets with VesselVioCell Reports Methods202212
47Simultaneous visualization of flow fields and oxygen concentrations to unravel transport and metabolic processes in biological systemsCell Reports Methods202212
48Functional microvascularization of human myocardium in vitroCell Reports Methods202212
49Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodiesCell Reports Methods202111
50Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISHCell Reports Methods202111