# | Title | Journal | Year | Citations |
---|
1 | A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases | ACS Combinatorial Science | 1999 | 2,037 |
2 | Increasing Rates of Reaction: Microwave-Assisted Organic Synthesis for Combinatorial Chemistry | ACS Combinatorial Science | 2002 | 348 |
3 | Chemography: The Art of Navigating in Chemical Space | ACS Combinatorial Science | 2001 | 320 |
4 | Comprehensive Survey of Combinatorial Library Synthesis: 1998 | ACS Combinatorial Science | 1999 | 284 |
5 | Recent Advances in the Preparation of Heterocycles on Solid Support: A Review of the Literature | ACS Combinatorial Science | 2000 | 279 |
6 | Scaffold Architecture and Pharmacophoric Properties of Natural Products and Trade Drugs: Application in the Design of Natural Product-Based Combinatorial Libraries | ACS Combinatorial Science | 2001 | 270 |
7 | Efficient One-Pot Synthesis of Spirooxindole Derivatives Catalyzed byl-Proline in Aqueous Medium | ACS Combinatorial Science | 2010 | 259 |
8 | ChemMatrix, a Poly(ethylene glycol)-Based Support for the Solid-Phase Synthesis of Complex Peptides | ACS Combinatorial Science | 2006 | 241 |
9 | Automated Library Generation Using Sequential Microwave-Assisted Chemistry. Application toward the Biginelli Multicomponent Condensation | ACS Combinatorial Science | 2001 | 233 |
10 | Comprehensive Survey of Combinatorial Library Synthesis: 2005 | ACS Combinatorial Science | 2006 | 219 |
11 | Application of Combinatorial Chemistry Science on Modern Drug Discovery | ACS Combinatorial Science | 2008 | 206 |
12 | Combinatorial Lead Optimization of [1,2]-Diamines Based on Ethambutol as Potential Antituberculosis Preclinical Candidates | ACS Combinatorial Science | 2003 | 205 |
13 | Comprehensive Survey of Combinatorial Library Synthesis: 2000 | ACS Combinatorial Science | 2001 | 194 |
14 | Comprehensive Survey of Combinatorial Library Synthesis: 1999 | ACS Combinatorial Science | 2000 | 183 |
15 | Solution- and Solid-Phase Strategies for the Design, Synthesis, and Screening of Libraries Based on Natural Product Templates: A Comprehensive Survey | ACS Combinatorial Science | 2001 | 182 |
16 | In Situ Generation of Carbon Monoxide from Solid Molybdenum Hexacarbonyl. A Convenient and Fast Route to Palladium-Catalyzed Carbonylation Reactions | ACS Combinatorial Science | 2002 | 171 |
17 | Beyond Mere Diversity: Tailoring Combinatorial Libraries for Drug Discovery | ACS Combinatorial Science | 1999 | 170 |
18 | Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones by Three-Component Coupling of Isatoic Anhydride, Amines, and Aldehydes Catalyzed by Magnetic Fe3O4 Nanoparticles in Water | ACS Combinatorial Science | 2010 | 170 |
19 | Combinatorial Electrochemical Screening of Fuel Cell Electrocatalysts | ACS Combinatorial Science | 2004 | 164 |
20 | Continuous-Flow High Pressure Hydrogenation Reactor for Optimization and High-Throughput Synthesis | ACS Combinatorial Science | 2006 | 159 |
21 | Diversity Oriented Synthesis of Benzoxanthene and Benzochromene Libraries via One-Pot, Three-Component Reactions and Their Anti-proliferative Activity | ACS Combinatorial Science | 2010 | 153 |
22 | Solid-Phase Organic Synthesis: A Critical Understanding of the Resin† | ACS Combinatorial Science | 2000 | 152 |
23 | Combinatorial Library of Peptidotriazoles: Identification of [1,2,3]-Triazole Inhibitors against a RecombinantLeishmaniamexicanaCysteine Protease | ACS Combinatorial Science | 2004 | 147 |
24 | Automated Electrochemical Synthesis and Photoelectrochemical Characterization of Zn1-xCoxO Thin Films for Solar Hydrogen Production | ACS Combinatorial Science | 2005 | 147 |
25 | Efficient One-Pot Synthesis of Novel Spirooxindole Derivatives via Three-Component Reaction in Aqueous Medium | ACS Combinatorial Science | 2010 | 142 |
26 | Catalyst-Free One-Pot Four Component Synthesis of Polysubstituted Imidazoles in Neutral Ionic Liquid 1-Butyl-3-methylimidazolium Bromide | ACS Combinatorial Science | 2010 | 141 |
27 | Combinatorial Approach to the Development of a Single Mass YVO4:Bi3+,Eu3+ Phosphor with Red and Green Dual Colors for High Color Rendering White Light-Emitting Diodes | ACS Combinatorial Science | 2010 | 140 |
28 | High-Throughput Screening Using Porous Photoelectrode for the Development of Visible-Light-Responsive Semiconductors | ACS Combinatorial Science | 2007 | 136 |
29 | Comprehensive Survey of Combinatorial Library Synthesis: 2003 | ACS Combinatorial Science | 2004 | 133 |
30 | meso-Tetra(pentafluorophenyl)porphyrin as an Efficient Platform for Combinatorial Synthesis and the Selection of New Photodynamic Therapeutics using a Cancer Cell Line | ACS Combinatorial Science | 2007 | 133 |
31 | Combining Biginelli Multicomponent and Click Chemistry: Generation of 6-(1,2,3-Triazol-1-yl)-Dihydropyrimidone Libraries | ACS Combinatorial Science | 2004 | 132 |
32 | Solid-Phase Synthesis of Biologically Active Benzoannelated Nitrogen Heterocycles: An Update | ACS Combinatorial Science | 2009 | 131 |
33 | Novel One-Pot, Three-Component Synthesis of Spiro[Indoline-pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidine]trione Library | ACS Combinatorial Science | 2009 | 124 |
34 | Comprehensive Survey of Combinatorial Library Synthesis: 2001 | ACS Combinatorial Science | 2002 | 123 |
35 | Comprehensive Survey of Combinatorial Library Synthesis: 2002 | ACS Combinatorial Science | 2003 | 122 |
36 | Synthesis of 2-Aminobenzothiazole via Copper(I)-Catalyzed Tandem Reaction of 2-Iodobenzenamine with Isothiocyanate | ACS Combinatorial Science | 2009 | 121 |
37 | Microwave-Assisted Three-Component Synthesis of 7-Aryl-2-alkylthio-4,7-dihydro-1,2,4-triazolo[1,5-a]-pyrimidine-6-carboxamides and Their Selective Reduction | ACS Combinatorial Science | 2006 | 114 |
38 | Spatially Addressed Synthesis of Amino- and Amino-Oxy-Substituted 1,3,5-Triazine Arrays on Polymeric Membranes | ACS Combinatorial Science | 2000 | 113 |
39 | Combinatorial Electrochemical Synthesis and Characterization of Tungsten-Based Mixed-Metal Oxides | ACS Combinatorial Science | 2002 | 113 |
40 | Parallel Personal Comments on “Classical” Papers in Combinatorial Chemistry | ACS Combinatorial Science | 1999 | 110 |
41 | An Alkylsilyl-Tethered, High-Capacity Solid Support Amenable to Diversity-Oriented Synthesis for One-Bead, One-Stock Solution Chemical Genetics | ACS Combinatorial Science | 2001 | 110 |
42 | Multicomponent Reactions to Form Heterocycles by Microwave-Assisted Continuous Flow Organic Synthesis | ACS Combinatorial Science | 2007 | 110 |
43 | Microwave-Assisted Combinatorial Synthesis of Hexa-Substituted 1,4-Dihydropyridines Scaffolds Using One-Pot Two-Step Multicomponent Reaction followed by a S-Alkylation | ACS Combinatorial Science | 2008 | 110 |
44 | New Convenient Four-Component Synthesis of 6-Amino-2,4-dihydropyrano[2,3-c]pyrazol-5-carbonitriles and One-Pot Synthesis of 6′-Aminospiro[(3H)-indol-3,4′-pyrano[2,3-c]pyrazol]-(1H)-2-on-5′-carbonitriles | ACS Combinatorial Science | 2009 | 110 |
45 | Novel One-Pot Three- and Pseudo-Five-Component Reactions: Synthesis of Functionalized Benzo[g]- and Dihydropyrano[2,3-g]chromene Derivatives | ACS Combinatorial Science | 2009 | 109 |
46 | Strategies for the Use of Mixture-Based Synthetic Combinatorial Libraries: Scaffold Ranking, Direct Testing In Vivo, and Enhanced Deconvolution by Computational Methods | ACS Combinatorial Science | 2008 | 108 |
47 | Concise and Versatile Multicomponent Synthesis of Multisubstituted Polyfunctional Dihydropyrroles | ACS Combinatorial Science | 2009 | 105 |
48 | Sulfonic Acid Functionalized Ionic Liquid in Combinatorial Approach, a Recyclable and Water Tolerant-Acidic Catalyst for One-Pot Friedlander Quinoline Synthesis | ACS Combinatorial Science | 2010 | 105 |
49 | The Recent Impact of Solid-Phase Synthesis on Medicinally Relevant Benzoannelated Oxygen Heterocycles | ACS Combinatorial Science | 2005 | 103 |
50 | Efficient Synthesis of Spiro[chromeno[2,3-d]pyrimidine-5,3′-indoline]-tetraones by a One-Pot and Three-Component Reaction | ACS Combinatorial Science | 2009 | 103 |