| # | Title | Journal | Year | Citations |
|---|
| 1 | Transcription Factors Associated with Abiotic and Biotic Stress Tolerance and Their Potential for Crops Improvement | Genes | 2019 | 348 |
| 2 | Genetics of Type 2 Diabetes—Pitfalls and Possibilities | Genes | 2015 | 337 |
| 3 | Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease | Genes | 2019 | 291 |
| 4 | Disease Resistance Mechanisms in Plants | Genes | 2018 | 290 |
| 5 | Signaling Pathways in Exosomes Biogenesis, Secretion and Fate | Genes | 2013 | 285 |
| 6 | MYC Deregulation in Primary Human Cancers | Genes | 2017 | 281 |
| 7 | Advances in Non-Viral DNA Vectors for Gene Therapy | Genes | 2017 | 279 |
| 8 | Satellite DNA: An Evolving Topic | Genes | 2017 | 277 |
| 9 | CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function | Genes | 2017 | 269 |
| 10 | Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7) | Genes | 2016 | 266 |
| 11 | Whole Genome Analyses Suggests that Burkholderia sensu lato Contains Two Additional Novel Genera (Mycetohabitans gen. nov., and Trinickia gen. nov.): Implications for the Evolution of Diazotrophy and Nodulation in the Burkholderiaceae | Genes | 2018 | 252 |
| 12 | Microfluidic Devices for Drug Delivery Systems and Drug Screening | Genes | 2018 | 252 |
| 13 | Genome Size Diversity and Its Impact on the Evolution of Land Plants | Genes | 2018 | 244 |
| 14 | DNA Methylation Biomarkers: Cancer and Beyond | Genes | 2014 | 236 |
| 15 | The Mitochondrial Basis of Aging and Age-Related Disorders | Genes | 2017 | 228 |
| 16 | tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA | Genes | 2018 | 217 |
| 17 | DNA Methylation Reprogramming during Mammalian Development | Genes | 2019 | 215 |
| 18 | Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists | Genes | 2018 | 212 |
| 19 | Circular RNAs (circRNAs) in Health and Disease | Genes | 2017 | 211 |
| 20 | Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae | Genes | 2020 | 210 |
| 21 | Machine Learning and Integrative Analysis of Biomedical Big Data | Genes | 2019 | 208 |
| 22 | Molecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNA | Genes | 2015 | 205 |
| 23 | Genetics of Charcot-Marie-Tooth (CMT) Disease within the Frame of the Human Genome Project Success | Genes | 2014 | 203 |
| 24 | Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations | Genes | 2020 | 185 |
| 25 | The Complex Relationship between Virulence and Antibiotic Resistance | Genes | 2017 | 183 |
| 26 | A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma | Genes | 2022 | 178 |
| 27 | Role of the Extremolytes Ectoine and Hydroxyectoine as Stress Protectants and Nutrients: Genetics, Phylogenomics, Biochemistry, and Structural Analysis | Genes | 2018 | 177 |
| 28 | NF-kappaB: Two Sides of the Same Coin | Genes | 2018 | 173 |
| 29 | The SaeRS Two‐Component System of Staphylococcus aureus | Genes | 2016 | 170 |
| 30 | Physical Activity and Brain Health | Genes | 2019 | 170 |
| 31 | Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability | Genes | 2020 | 170 |
| 32 | Ketogenic Diet and Microbiota: Friends or Enemies? | Genes | 2019 | 166 |
| 33 | RNA Editing and Its Molecular Mechanism in Plant Organelles | Genes | 2017 | 164 |
| 34 | Programming Pluripotent Precursor Cells Derived from Xenopus Embryos to Generate Specific Tissues and Organs | Genes | 2010 | 163 |
| 35 | Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas | Genes | 2020 | 163 |
| 36 | Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens | Genes | 2018 | 161 |
| 37 | Beyond Biodiversity: Can Environmental DNA (eDNA) Cut It as a Population Genetics Tool? | Genes | 2019 | 160 |
| 38 | Dietary Fiber Treatment Corrects the Composition of Gut Microbiota, Promotes SCFA Production, and Suppresses Colon Carcinogenesis | Genes | 2018 | 158 |
| 39 | Next Generation Sequencing of Ancient DNA: Requirements, Strategies and Perspectives | Genes | 2010 | 157 |
| 40 | The Cell Killing Mechanisms of Hydroxyurea | Genes | 2016 | 154 |
| 41 | The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation | Genes | 2013 | 152 |
| 42 | The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery | Genes | 2020 | 151 |
| 43 | SCINA: Semi-Supervised Analysis of Single Cells in Silico | Genes | 2019 | 150 |
| 44 | Telomeres and Telomerase in Cardiovascular Diseases | Genes | 2016 | 147 |
| 45 | Targeting MicroRNAs in Cancer Gene Therapy | Genes | 2017 | 147 |
| 46 | Quorum Sensing Regulation of Competence and Bacteriocins in Streptococcus pneumoniae and mutans | Genes | 2017 | 143 |
| 47 | Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA | Genes | 2018 | 143 |
| 48 | Molecular Functions of Long Non-Coding RNAs in Plants | Genes | 2012 | 139 |
| 49 | The Role of Transposable Elements in Speciation | Genes | 2018 | 139 |
| 50 | Thyroid Cancer in the Pediatric Population | Genes | 2019 | 139 |
