| # | Title | Journal | Year | Citations |
|---|
| 1 | Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence | Proteomics | 2004 | 1,784 |
| 2 | Current two-dimensional electrophoresis technology for proteomics | Proteomics | 2004 | 1,533 |
| 3 | Comet: An open‐source MS/MS sequence database search tool | Proteomics | 2013 | 1,175 |
| 4 | FunRich: An open access standalone functional enrichment and interaction network analysis tool | Proteomics | 2015 | 1,145 |
| 5 | Matrigel: A complex protein mixture required for optimal growth of cell culture | Proteomics | 2010 | 1,123 |
| 6 | Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology | Proteomics | 2001 | 881 |
| 7 | A novel experimental design for comparative two-dimensional gel analysis: Two-dimensional difference gel electrophoresis incorporating a pooled internal standard | Proteomics | 2003 | 856 |
| 8 | Predotar: A tool for rapidly screening proteomes forN-terminal targeting sequences | Proteomics | 2004 | 817 |
| 9 | Proteomic profiling of exosomes: Current perspectives | Proteomics | 2008 | 767 |
| 10 | Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database | Proteomics | 2005 | 766 |
| 11 | ExoCarta: A compendium of exosomal proteins and RNA | Proteomics | 2009 | 756 |
| 12 | A guided tour of the Trans‐Proteomic Pipeline | Proteomics | 2010 | 710 |
| 13 | Protein labeling by iTRAQ: A new tool for quantitative mass spectrometry in proteome research | Proteomics | 2007 | 699 |
| 14 | The International Protein Index: An integrated database for proteomics experiments | Proteomics | 2004 | 685 |
| 15 | Less label, more free: Approaches in label‐free quantitative mass spectrometry | Proteomics | 2011 | 613 |
| 16 | Reversed‐phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells | Proteomics | 2011 | 564 |
| 17 | Functional and topological characterization of protein interaction networks | Proteomics | 2004 | 563 |
| 18 | Methods for the detection and analysis of protein–protein interactions | Proteomics | 2007 | 554 |
| 19 | PRIDE: The proteomics identifications database | Proteomics | 2005 | 553 |
| 20 | Gram‐positive bacteria produce membrane vesicles: Proteomics‐based characterization of Staphylococcus aureus‐derived membrane vesicles | Proteomics | 2009 | 532 |
| 21 | Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures | Proteomics | 2009 | 521 |
| 22 | Using iRT, a normalized retention time for more targeted measurement of peptides | Proteomics | 2012 | 517 |
| 23 | HUPO Plasma Proteome Project specimen collection and handling: Towards the standardization of parameters for plasma proteome samples | Proteomics | 2005 | 515 |
| 24 | PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation | Proteomics | 2004 | 512 |
| 25 | The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins | Proteomics | 2003 | 508 |
| 26 | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma | Proteomics | 2013 | 501 |
| 27 | Improved silver staining protocols for high sensitivity protein identification using matrix-assisted laser desorption/ionization-time of flight analysis | Proteomics | 2001 | 496 |
| 28 | Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell‐lines | Proteomics | 2015 | 493 |
| 29 | Human body fluid proteome analysis | Proteomics | 2006 | 488 |
| 30 | Development and validation of a spectral library searching method for peptide identification from MS/MS | Proteomics | 2007 | 487 |
| 31 | Scaffold: A bioinformatic tool for validating MS/MS‐based proteomic studies | Proteomics | 2010 | 482 |
| 32 | GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis | Proteomics | 2019 | 479 |
| 33 | A novel strategy for quantitative proteomics using isotope-coded protein labels | Proteomics | 2005 | 477 |
| 34 | Metabolomics: Current technologies and future trends | Proteomics | 2006 | 471 |
| 35 | The detection, correlation, and comparison of peptide precursor and product ions from data independent LC‐MS with data dependant LC‐MS/MS | Proteomics | 2009 | 460 |
| 36 | Preparation of protein extracts from recalcitrant plant tissues: An evaluation of different methods for two-dimensional gel electrophoresis analysis | Proteomics | 2005 | 447 |
| 37 | Cell surface protein glycosylation in cancer | Proteomics | 2014 | 436 |
| 38 | GlycoMod - A software tool for determining glycosylation compositions from mass spectrometric data | Proteomics | 2001 | 434 |
| 39 | Analytical strategies for phosphoproteomics | Proteomics | 2009 | 434 |
| 40 | Proteomic analysis of salt stress-responsive proteins in rice root | Proteomics | 2005 | 433 |
| 41 | An accurate mass tag strategy for quantitative and high-throughput proteome measurements | Proteomics | 2002 | 423 |
| 42 | Proteomics, transcriptomics and lipidomics of exosomes and ectosomes | Proteomics | 2013 | 416 |
| 43 | Proteomic analysis of rice leaves during drought stress and recovery | Proteomics | 2002 | 415 |
| 44 | Quantification of C-reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and13C-labeled peptide standards | Proteomics | 2004 | 400 |
| 45 | Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks | Proteomics | 2004 | 398 |
| 46 | Antibody microarray profiling of human prostate cancer sera: Antibody screening and identification of potential biomarkers | Proteomics | 2003 | 394 |
| 47 | Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology | Proteomics | 2003 | 381 |
| 48 | Multi-component immunoaffinity subtraction chromatography: An innovative step towards a comprehensive survey of the human plasma proteome | Proteomics | 2003 | 374 |
| 49 | A critical evaluation of sample extraction techniques for enhanced proteomic analysis of recalcitrant plant tissues | Proteomics | 2004 | 374 |
| 50 | Characterization of phosphoproteins from electrophoretic gels by nanoscale Fe(III) affinity chromatography with off-line mass spectrometry analysis | Proteomics | 2001 | 371 |
