4.6(top 5%)
impact factor
15.3K(top 1%)
papers
847.4K(top 1%)
citations
325(top 1%)
h-index
4.6(top 10%)
impact factor
24.6K
all documents
881.9K
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543(top 1%)
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Top Articles

#TitleJournalYearCitations
1Antioxidant activity applying an improved ABTS radical cation decolorization assayFree Radical Biology and Medicine199917,909
2Structure-antioxidant activity relationships of flavonoids and phenolic acidsFree Radical Biology and Medicine19967,080
3Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydesFree Radical Biology and Medicine19915,908
4Oxidative stress, inflammation, and cancer: How are they linked?Free Radical Biology and Medicine20103,991
5Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione coupleFree Radical Biology and Medicine20013,895
6Oxidative mechanisms in the toxicity of metal ionsFree Radical Biology and Medicine19953,576
7Reactive oxygen species, cellular redox systems, and apoptosisFree Radical Biology and Medicine20102,779
8Mitochondrial free radical generation, oxidative stress, and aging11This article is dedicated to the memory of our dear friend, colleague, and mentor Lars Ernster (1920–1998), in gratitude for all he gave to us.Free Radical Biology and Medicine20002,556
9Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injuryFree Radical Biology and Medicine19902,244
10Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.Free Radical Biology and Medicine20012,223
11Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the United States Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable.Free Radical Biology and Medicine19992,078
12Oxidative Stress Hypothesis in Alzheimer's DiseaseFree Radical Biology and Medicine19972,055
13The role of lipid peroxidation and antioxidants in oxidative modification of LDLFree Radical Biology and Medicine19922,054
14Antioxidant and Prooxidant Behavior of Flavonoids: Structure-Activity RelationshipsFree Radical Biology and Medicine19971,917
15Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expressionFree Radical Biology and Medicine20021,720
16Alpha-lipoic acid as a biological antioxidantFree Radical Biology and Medicine19951,709
17Flavonoids: antioxidants or signalling molecules?Free Radical Biology and Medicine20041,705
18The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acidFree Radical Biology and Medicine19891,576
19Spin Trapping: ESR parameters of spin adducts 1474 1528VFree Radical Biology and Medicine19871,559
20The thioredoxin antioxidant systemFree Radical Biology and Medicine20141,476
21Glutathione and its role in cellular functionsFree Radical Biology and Medicine19991,435
22Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitationsFree Radical Biology and Medicine20121,424
23Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxideFree Radical Biology and Medicine19981,369
24Nrf2:INrf2 (Keap1) signaling in oxidative stressFree Radical Biology and Medicine20091,359
25Oxygen-radical absorbance capacity assay for antioxidantsFree Radical Biology and Medicine19931,252
26Oxidants as Stimulators of Signal TransductionFree Radical Biology and Medicine19971,252
27The role of oxidized lipoproteins in atherogenesisFree Radical Biology and Medicine19961,238
28Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signalingFree Radical Biology and Medicine20051,232
29Triggering and modulation of apoptosis by oxidative stressFree Radical Biology and Medicine20001,165
30Oxidative stress and gene regulationFree Radical Biology and Medicine20001,109
31Nrf2 signaling in coordinated activation of antioxidant gene expressionFree Radical Biology and Medicine20041,093
32Vitamin E, antioxidant and nothing moreFree Radical Biology and Medicine20071,076
33Superoxide and hydrogen peroxide in relation to mammalian cell proliferationFree Radical Biology and Medicine19951,069
34Oxidative stress, insulin signaling, and diabetesFree Radical Biology and Medicine20111,064
35Structural aspects of antioxidant activity of flavonoidsFree Radical Biology and Medicine19961,040
36Thiol chemistry and specificity in redox signalingFree Radical Biology and Medicine20081,039
37Biologic and pharmacologic regulation of mammalian glutathione synthesisFree Radical Biology and Medicine19991,018
38Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequencesFree Radical Biology and Medicine19901,005
39Importance of SE-glutathione peroxidase, catalase, and CU/ZN-SOD for cell survival against oxidative stressFree Radical Biology and Medicine1994996
40Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissuesFree Radical Biology and Medicine1996986
41Antioxidant potential of ferulic acidFree Radical Biology and Medicine1992937
42Tissue-specific functions of individual glutathione peroxidasesFree Radical Biology and Medicine1999931
43Free radicals, antioxidant enzymes, and carcinogenesisFree Radical Biology and Medicine1990920
44Mitochondria and reactive oxygen speciesFree Radical Biology and Medicine2009904
45Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteinsFree Radical Biology and Medicine2004900
46Free radicals and diabetesFree Radical Biology and Medicine1988899
47Reactions of oxyl radicals with DNAFree Radical Biology and Medicine1995899
48Trends in oxidative aging theoriesFree Radical Biology and Medicine2007897
49Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress 1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.Free Radical Biology and Medicine2002893
50Measurement of F2-isoprostanes as an index of oxidative stress in vivoFree Radical Biology and Medicine2000885