| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 | Science | 2008 | 1.9K |
| Cancer cell metabolism: Warburg and beyond | Cell | 2008 | 1.6K |
| Defining the role of the MHC in autoimmunity: a review and pooled analysis | PLoS Genetics | 2008 | 400 |
| Distinct microRNA expression profiles in acute myeloid leukemia with common translocations | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 375 |
| Origin and function of olfactory bulb interneuron diversity | Trends in Neurosciences | 2008 | 323 |
| SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma | Blood | 2008 | 262 |
| Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant | PLoS ONE | 2008 | 261 |
| Members of the miRNA-200 family regulate olfactory neurogenesis | Neuron | 2008 | 218 |
| Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity | PLoS Medicine | 2008 | 218 |
| DNA triplexes and Friedreich ataxia | FASEB Journal | 2008 | 114 |
| The PDGF signaling pathway controls multiple steroid-producing lineages | Genes and Development | 2008 | 87 |
| Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties | Genome Research | 2008 | 79 |
| Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics | 2008 | 78 |
| Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 73 |
| Long intronic GAA*TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia | Nucleic Acids Research | 2008 | 62 |
| Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells | Brain | 2008 | 61 |
| Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity | Journal of Molecular Biology | 2008 | 52 |
| In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis | Development (Cambridge) | 2008 | 48 |
| Genome wide survey, discovery and evolution of repetitive elements in three Entamoeba species | BMC Genomics | 2008 | 47 |
| The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 46 |
| Increasing ecological inference from high throughput sequencing of fungi in the environment through a tagging approach | Molecular Ecology Resources | 2008 | 41 |
| Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes | PLoS Computational Biology | 2008 | 41 |
| Stroke risk prediction model: a risk profile from the Korean study | Atherosclerosis | 2008 | 40 |
| CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma | International Journal of Cancer | 2008 | 40 |
| Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish | Developmental Dynamics | 2008 | 33 |
