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Top Articles

#TitleJournalYearCitations
1A CRISPR–Cpf1 system for efficient genome editing and transcriptional repression in plantsNature Plants2017425
2NMRbox: A Resource for Biomolecular NMR ComputationBiophysical Journal2017336
3The emerging and uncultivated potential of CRISPR technology in plant scienceNature Plants2019294
4Endolysins as AntimicrobialsAdvances in Virus Research2012291
5Critical assessment of methods of protein structure prediction (CASP)—Round XIVProteins: Structure, Function and Bioinformatics2021281
6A Large-Scale, Higher-Level, Molecular Phylogenetic Study of the Insect Order Lepidoptera (Moths and Butterflies)PLoS ONE2013253
7Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR dataJournal of Biomolecular NMR2017238
8A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in riceGenome Biology2018230
9The emerging landscape of single-molecule protein sequencing technologiesNature Methods2021198
10Plant genome editing with TALEN and CRISPRCell and Bioscience2017197
11‘ Candidatus Phytoplasma solani’, a novel taxon associated with stolbur- and bois noir-related diseases of plantsInternational Journal of Systematic and Evolutionary Microbiology2013190
12Critical assessment of methods of protein structure prediction (CASP)—round IXProteins: Structure, Function and Bioinformatics2011187
13Two-Way Chemical Communication between Artificial and Natural CellsACS Central Science2017178
14Purification and Characterization of Biofilm-Associated EPS Exopolysaccharides from ESKAPE Organisms and Other PathogensPLoS ONE2013178
15Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental MethodsJournal of the American Chemical Society2016171
16Proteins that switch foldsCurrent Opinion in Structural Biology2010170
17CRISPR-Cas9 Based Genome Editing Reveals New Insights into MicroRNA Function and Regulation in RiceFrontiers in Plant Science2017150
18Cysteine proteinase SpeB from Streptococcus pyogenes – a potent modifier of immunologically important host and bacterial proteinsBiological Chemistry2011138
19De novo protein design enables the precise induction of RSV-neutralizing antibodiesScience2020137
20Plant Genome Editing Using FnCpf1 and LbCpf1 Nucleases at Redefined and Altered PAM SitesMolecular Plant2018136
21Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding proteinProceedings of the National Academy of Sciences of the United States of America2017135
22Molecular Characterization of Vegetative Incompatibility Genes That Restrict Hypovirus Transmission in the Chestnut Blight Fungus Cryphonectria parasiticaGenetics2012128
23Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic HeterogeneityFrontiers in Oncology2018122
24HIV-1 Fitness Cost Associated with Escape from the VRC01 Class of CD4 Binding Site Neutralizing AntibodiesJournal of Virology2015121
25Electronic control of gene expression and cell behaviour in Escherichia coli through redox signallingNature Communications2017120
26Potent and broad HIV-neutralizing antibodies in memory B cells and plasmaScience Immunology2017119
27CRISPR–Cas12b enables efficient plant genome engineeringNature Plants2020116
28Amine Metabolomics of Hyperglycemic Endothelial Cells using Capillary LC–MS with Isobaric TaggingJournal of Proteome Research2011115
29Mycoviruses, RNA Silencing, and Viral RNA RecombinationAdvances in Virus Research2011114
30Mapping Monoclonal Antibody Structure by 2D 13C NMR at Natural AbundanceAnalytical Chemistry2015112
31Crystal structure of a complete ternary complex of T-cell receptor, peptide–MHC, and CD4Proceedings of the National Academy of Sciences of the United States of America2012108
32Developing next generation antimicrobials by intercepting AI-2 mediated quorum sensingEnzyme and Microbial Technology2011104
33Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of VulnerabilityCell2017103
34Expression profiles of human interferon‐alpha and interferon‐lambda subtypes are ligand‐ and cell‐dependentImmunology and Cell Biology201297
35Chitosan–Alginate Microcapsules Provide Gastric Protection and Intestinal Release of ICAM‐1‐Targeting Nanocarriers, Enabling GI Targeting In VivoAdvanced Functional Materials201693
36The structural biology of phenazine biosynthesisCurrent Opinion in Structural Biology201492
37CASP9 results compared to those of previous casp experimentsProteins: Structure, Function and Bioinformatics201191
38Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1Journal of Controlled Release201291
39Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytesClinical and Experimental Vaccine Research201591
40Plant virus directed fabrication of nanoscale materials and devicesVirology201589
41Rapid degradation of Streptococcus pyogenes biofilms by PlyC, a bacteriophage-encoded endolysinJournal of Antimicrobial Chemotherapy201388
42A Quantitative Chemical Proteomics Approach to Profile the Specific Cellular Targets of Andrographolide, a Promising Anticancer Agent That Suppresses Tumor MetastasisMolecular and Cellular Proteomics201488
43Mutational Tipping Points for Switching Protein Folds and FunctionsStructure201287
44Amplified and in Situ Detection of Redox-Active Metabolite Using a Biobased Redox CapacitorAnalytical Chemistry201386
45Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine designProceedings of the National Academy of Sciences of the United States of America201686
46Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese DonorImmunity201685
47Electrodeposition of a Biopolymeric Hydrogel: Potential for One-Step Protein ElectroaddressingBiomacromolecules201282
48A molecular phylogeny for the oldest (nonditrysian) lineages of extant Lepidoptera, with implications for classification, comparative morphology and life‐history evolutionSystematic Entomology201582
49Site-specific incorporation of phosphotyrosine using an expanded genetic codeNature Chemical Biology201782
50X-ray crystal structure of the streptococcal specific phage lysin PlyCProceedings of the National Academy of Sciences of the United States of America201280