| # | Title | Journal | Year | Citations |
|---|
| 1 | Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study | Lancet Oncology, The | 2015 | 1,031 |
| 2 | MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions | International Journal of Molecular Sciences | 2016 | 882 |
| 3 | Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation | Journal of Experimental Medicine | 2011 | 565 |
| 4 | Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia | Blood | 2013 | 420 |
| 5 | Rituximab in B-Cell Hematologic Malignancies: A Review of 20 Years of Clinical Experience | Advances in Therapy | 2017 | 407 |
| 6 | Dasatinib as first-line treatment for adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia | Blood | 2011 | 395 |
| 7 | Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia | Blood | 2012 | 394 |
| 8 | Epigenetic Silencing of the Myelopoiesis Regulator microRNA-223 by the AML1/ETO Oncoprotein | Cancer Cell | 2007 | 373 |
| 9 | European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia | Leukemia | 2016 | 369 |
| 10 | The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development | Journal of Experimental Medicine | 2012 | 363 |
| 11 | Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness | Blood | 2011 | 342 |
| 12 | Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome–positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol | Blood | 2007 | 336 |
| 13 | The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation | Blood | 2011 | 316 |
| 14 | Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 September 2008 | Leukemia | 2010 | 302 |
| 15 | Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia | Blood | 2014 | 302 |
| 16 | Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group | Blood | 2010 | 290 |
| 17 | Chemotherapy plus lenalidomide versus autologous transplantation, followed by lenalidomide plus prednisone versus lenalidomide maintenance, in patients with multiple myeloma: a randomised, multicentre, phase 3 trial | Lancet Oncology, The | 2015 | 289 |
| 18 | Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab | Blood | 2009 | 273 |
| 19 | The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 266 |
| 20 | Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia | Blood | 2012 | 257 |
| 21 | Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data | Lancet Oncology, The | 2014 | 256 |
| 22 | Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1–positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP) | Blood | 2009 | 201 |
| 23 | Flow cytometric study of potential target antigens (CD19, CD20, CD22, CD33) for antibody-based immunotherapy in acute lymphoblastic leukemia: analysis of 552 cases | Leukemia and Lymphoma | 2011 | 199 |
| 24 | Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia | Blood | 2015 | 197 |
| 25 | WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO) | Blood | 2008 | 192 |
| 26 | PVT1: A Rising Star among Oncogenic Long Noncoding RNAs | BioMed Research International | 2015 | 191 |
| 27 | Diffuse large B-cell lymphoma genotyping on the liquid biopsy | Blood | 2017 | 183 |
| 28 | The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex | Genome Biology | 2017 | 179 |
| 29 | Acute promyelocytic leukemia: a model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia | Leukemia | 2002 | 178 |
| 30 | Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma | Blood | 2011 | 176 |
| 31 | Targeting the leukemic stem cell: the Holy Grail of leukemia therapy | Leukemia | 2009 | 174 |
| 32 | Prospective study of guideline‐tailored therapy with direct‐acting antivirals for hepatitis C virus‐associated mixed cryoglobulinemia | Hepatology | 2016 | 167 |
| 33 | Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation | Blood | 2012 | 166 |
| 34 | Predictive factors for the outcome of allogeneic transplantation in patients with MDS stratified according to the revised IPSS-R | Blood | 2014 | 162 |
| 35 | Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias | Blood | 2015 | 154 |
| 36 | A MALT lymphoma prognostic index | Blood | 2017 | 149 |
| 37 | The genetics of nodal marginal zone lymphoma | Blood | 2016 | 147 |
| 38 | Busulfan plus cyclophosphamide versus busulfan plus fludarabine as a preparative regimen for allogeneic haemopoietic stem-cell transplantation in patients with acute myeloid leukaemia: an open-label, multicentre, randomised, phase 3 trial | Lancet Oncology, The | 2015 | 143 |
| 39 | Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity | Journal of Biological Chemistry | 2009 | 139 |
| 40 | Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression | Blood | 2012 | 139 |
| 41 | Utility of baseline 18FDG-PET/CT functional parameters in defining prognosis of primary mediastinal (thymic) large B-cell lymphoma | Blood | 2015 | 138 |
| 42 | JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model | Blood | 2014 | 128 |
| 43 | BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells | Blood | 2008 | 121 |
| 44 | The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α | Hepatology | 2011 | 116 |
| 45 | ADP-ribose polymers localized on Ctcf–Parp1–Dnmt1 complex prevent methylation of Ctcf target sites | Biochemical Journal | 2012 | 110 |
| 46 | Markers of Myeloproliferative Diseases in Childhood Polycythemia Vera and Essential Thrombocythemia | Journal of Clinical Oncology | 2007 | 107 |
| 47 | Chlorambucil plus rituximab with or without maintenance rituximab as first‐line treatment for elderly chronic lymphocytic leukemia patients | American Journal of Hematology | 2014 | 104 |
| 48 | LncRNAs: New Players in Apoptosis Control | International Journal of Cell Biology | 2014 | 101 |
| 49 | Clinico-pathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution | Leukemia Research | 2004 | 100 |
| 50 | Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis | OncoImmunology | 2017 | 100 |
