| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Autism spectrum disorder | Lancet, The | 2018 | 1,220 |
| 4 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 5 | Ubiquitin is phosphorylated by PINK1 to activate parkin | Nature | 2014 | 1,185 |
| 6 | Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial | Lancet, The | 2012 | 1,041 |
| 7 | Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial | Lancet, The | 2012 | 1,040 |
| 8 | Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways | Science | 2015 | 823 |
| 9 | Differences between males and females in rates of serotonin synthesis in human brain | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 820 |
| 10 | Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double‐blind placebo‐controlled multicenter trial | Annals of Neurology | 2009 | 815 |
| 11 | Discharge of Identified Orexin/Hypocretin Neurons across the Sleep-Waking Cycle | Journal of Neuroscience | 2005 | 778 |
| 12 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 13 | Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results | Annals of Neurology | 1995 | 758 |
| 14 | iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases | Neuron | 2017 | 730 |
| 15 | Phosphoinositides as Regulators in Membrane Traffic | Science | 1996 | 719 |
| 16 | Graded persistent activity in entorhinal cortex neurons | Nature | 2002 | 719 |
| 17 | Microglial control of astrocytes in response to microbial metabolites | Nature | 2018 | 693 |
| 18 | Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging | Neurology | 1992 | 684 |
| 19 | Differential electroresponsiveness of stellate and pyramidal-like cells of medial entorhinal cortex layer II | Journal of Neurophysiology | 1993 | 642 |
| 20 | Functional localization and lateralization of human olfactory cortex | Nature | 1992 | 636 |
| 21 | Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons | Developmental Dynamics | 1992 | 628 |
| 22 | Isolation and Characterization of Multipotent Skin-Derived Precursors from Human Skin | Stem Cells | 2005 | 613 |
| 23 | Alzheimer’s disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategies | Progress in Neurobiology | 2002 | 595 |
| 24 | A presynaptic inositol-5-phosphatase | Nature | 1996 | 586 |
| 25 | A deep learning framework for neuroscience | Nature Neuroscience | 2019 | 563 |
| 26 | Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment | EMBO Reports | 2012 | 558 |
| 27 | Cortical Representation of the Sensory Dimension of Pain | Journal of Neurophysiology | 2001 | 549 |
| 28 | Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control | EMBO Journal | 2014 | 546 |
| 29 | Brain Volume and Metabolism in Fetuses With Congenital Heart Disease | Circulation | 2010 | 535 |
| 30 | Neurologic Sequelae of Domoic Acid Intoxication Due to the Ingestion of Contaminated Mussels | New England Journal of Medicine | 1990 | 533 |
| 31 | Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy | Nature Medicine | 1996 | 522 |
| 32 | SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse | Neuron | 2019 | 518 |
| 33 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 34 | Deactivation of the Limbic System During Acute Psychosocial Stress: Evidence from Positron Emission Tomography and Functional Magnetic Resonance Imaging Studies | Biological Psychiatry | 2008 | 516 |
| 35 | High-frequency oscillations during human focal seizures | Brain | 2006 | 486 |
| 36 | The NIH MRI study of normal brain development | NeuroImage | 2006 | 466 |
| 37 | RNA Cargoes Associating with FMRP Reveal Deficits in Cellular Functioning in Fmr1 Null Mice | Neuron | 2003 | 462 |
| 38 | Intraoperative brain cancer detection with Raman spectroscopy in humans | Science Translational Medicine | 2015 | 457 |
| 39 | New Clinical Subtypes of Parkinson Disease and Their Longitudinal Progression | JAMA Neurology | 2015 | 456 |
| 40 | Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro | Molecular and Cellular Biology | 2004 | 454 |
| 41 | Injectable Graphene Oxide/Hydrogel-Based Angiogenic Gene Delivery System for Vasculogenesis and Cardiac Repair | ACS Nano | 2014 | 449 |
| 42 | Interferon-γ confers resistance to experimental allergic encephalomyelitis | European Journal of Immunology | 1996 | 448 |
| 43 | Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease | Trends in Biochemical Sciences | 2015 | 444 |
| 44 | Focal neuronal migration disorders and intractable partial epilepsy: A study of 30 patients | Annals of Neurology | 1991 | 443 |
| 45 | Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation | Science | 2013 | 440 |
| 46 | Virtual Reality in Stroke Rehabilitation: A Systematic Review of its Effectiveness for Upper Limb Motor Recovery | Topics in Stroke Rehabilitation | 2007 | 439 |
| 47 | Dissociation of sensory and affective dimensions of pain using hypnotic modulation | Pain | 1999 | 432 |
| 48 | Cholinergic Basal Forebrain Neurons Burst with Theta during Waking and Paradoxical Sleep | Journal of Neuroscience | 2005 | 417 |
| 49 | Chronic stress, cognitive functioning and mental health | Neurobiology of Learning and Memory | 2011 | 411 |
| 50 | MRI volumetric measurement of amygdala and hippocampus in temporal lobe epilepsy | Neurology | 1993 | 409 |
