# | Title | Journal | Year | Citations |
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1 | The Biogenesis of Lysosomes | Annual Review of Cell Biology | 1989 | 1,538 |
2 | The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Nature | 2001 | 902 |
3 | Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia | Science Translational Medicine | 2016 | 621 |
4 | SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 421 |
5 | Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies | Nature Genetics | 2009 | 383 |
6 | INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse | Nature Genetics | 2009 | 323 |
7 | Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly | Cell | 2008 | 300 |
8 | The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 272 |
9 | TISSUE FACTOR PATHWAY INHIBITOR AND THE REVISED THEORY OF COAGULATION | Annual Review of Medicine | 1995 | 272 |
10 | Targeted disruption of the murine tissue factor gene results in embryonic lethality | Blood | 1996 | 271 |
11 | Tissue Factor Pathway Inhibitor Gene Disruption Produces Intrauterine Lethality in Mice | Blood | 1997 | 252 |
12 | G6PD deficiency: the genotype-phenotype association | Blood Reviews | 2007 | 230 |
13 | The Role of Phosphatases in Inositol Signaling Reactions | Journal of Biological Chemistry | 1999 | 212 |
14 | The role of human ribosomal proteins in the maturation of rRNA and ribosome production | Rna | 2008 | 210 |
15 | The trans-Golgi network: a late secretory sorting station | Current Opinion in Cell Biology | 1997 | 208 |
16 | American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults | Blood Advances | 2020 | 206 |
17 | Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 179 |
18 | Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure | Blood Cells, Molecules, and Diseases | 2005 | 174 |
19 | Asparagine-linked Oligosaccharides Protect Lamp-1 and Lamp-2 from Intracellular Proteolysis | Journal of Biological Chemistry | 1999 | 167 |
20 | The Inositol 5′-Phosphatase SHIP Binds to Immunoreceptor Signaling Motifs and Responds to High Affinity IgE Receptor Aggregation | Journal of Biological Chemistry | 1996 | 166 |
21 | Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model | Blood | 2010 | 159 |
22 | PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells | Molecular Cell | 2020 | 148 |
23 | Effect of eculizumab on haemolysis‐associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria | British Journal of Haematology | 2010 | 137 |
24 | The Isolation and Characterization of a cDNA Encoding Phospholipid-specific Inositol Polyphosphate 5-Phosphatase | Journal of Biological Chemistry | 2000 | 136 |
25 | Tissue factor pathway inhibitor: structure-function | Frontiers in Bioscience - Landmark | 2012 | 135 |
26 | Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates | Nature Medicine | 2003 | 134 |
27 | The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 127 |
28 | Dyskeratosis Congenita - A Disease of Dysfunctional Telomere Maintenance | Current Molecular Medicine | 2005 | 124 |
29 | The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 118 |
30 | A Unique Dermatan Sulfate-like Glycosaminoglycan from Ascidian: | Journal of Biological Chemistry | 1995 | 116 |
31 | A view of human haematopoietic development from the Petri dish | Nature Reviews Molecular Cell Biology | 2017 | 110 |
32 | Ajuba LIM Proteins Are Snail/Slug Corepressors Required for Neural Crest Development in Xenopus | Developmental Cell | 2008 | 106 |
33 | The Rate of Internalization of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is Enhanced by Multivalent Ligand Binding | Journal of Biological Chemistry | 1999 | 102 |
34 | Endoplasmic Reticulum-associated Degradation of Mammalian Glycoproteins Involves Sugar Chain Trimming to Man6–5GlcNAc2 | Journal of Biological Chemistry | 2003 | 101 |
35 | O-Fucosylation Is Required for ADAMTS13 Secretion | Journal of Biological Chemistry | 2007 | 100 |
36 | ADP-Ribosylation Factor 1 Transiently Activates High-Affinity Adaptor Protein Complex AP-1 Binding Sites On Golgi Membranes | Molecular Biology of the Cell | 1998 | 99 |
37 | The cDNA Cloning and Characterization of Inositol Polyphosphate 4-Phosphatase Type II | Journal of Biological Chemistry | 1997 | 94 |
38 | Cytokine production in myelofibrosis exhibits differential responsiveness to JAK-STAT, MAP kinase, and NFκB signaling | Leukemia | 2019 | 94 |
39 | Effect of tissue factor deficiency on mouse and tumor development | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 93 |
40 | Cells depleted for RPS19, a protein associated with Diamond Blackfan Anemia, show defects in 18S ribosomal RNA synthesis and small ribosomal subunit production | Blood Cells, Molecules, and Diseases | 2007 | 91 |
41 | Inositol 1,3,4-Trisphosphate 5/6-Kinase Associates with the COP9 Signalosome by Binding to CSN1 | Journal of Biological Chemistry | 2002 | 90 |
42 | Phosphoinositide-specific Inositol Polyphosphate 5-Phosphatase IV Inhibits Akt/Protein Kinase B Phosphorylation and Leads to Apoptotic Cell Death | Journal of Biological Chemistry | 2002 | 89 |
43 | Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice | Blood | 1997 | 86 |
44 | Distinct Tyrosine Kinase Activation and Triton X-100 Insolubility upon FcγRII or FcγRIIIB Ligation in Human Polymorphonuclear Leukocytes. | Journal of Biological Chemistry | 1995 | 84 |
45 | A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 83 |
46 | The Spectrum of Somatic Mutations in thePIG-AGene in Paroxysmal Nocturnal Hemoglobinuria Includes Large Deletions and Small Duplications | Blood Cells, Molecules, and Diseases | 1998 | 79 |
47 | Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 79 |
48 | ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial | Blood Advances | 2020 | 77 |
49 | Peters Plus Syndrome Mutations Disrupt a Noncanonical ER Quality-Control Mechanism | Current Biology | 2015 | 75 |
50 | Dyskeratosis congenita | FEBS Letters | 2010 | 73 |