| # | Title | Journal | Year | Citations |
|---|
| 1 | Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li–Fraumeni syndrome | Nature | 1990 | 1,156 |
| 2 | Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1 | Science | 1999 | 879 |
| 3 | Human aminopeptidase N is a receptor for human coronavirus 229E | Nature | 1992 | 843 |
| 4 | Genome Sequence and Comparative Analysis of the Solvent-Producing Bacterium Clostridium acetobutylicum | Journal of Bacteriology | 2001 | 725 |
| 5 | Tat trans-activates the human immunodeficiency virus through a nascent RNA target | Cell | 1989 | 714 |
| 6 | The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy | Acta Neuropathologica | 2016 | 708 |
| 7 | Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 398 |
| 8 | Protein Oxidation Implicated as the Primary Determinant of Bacterial Radioresistance | PLoS Biology | 2007 | 375 |
| 9 | Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV | Journal of Virology | 1991 | 345 |
| 10 | Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments | Nature Biotechnology | 2000 | 322 |
| 11 | Cloning of infectious adeno-associated virus genomes in bacterial plasmids | Gene | 1983 | 307 |
| 12 | Enhancement of wound healing by curcumin in animals | Wound Repair and Regeneration | 1998 | 306 |
| 13 | Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans | PLoS ONE | 2010 | 278 |
| 14 | Thymosin β4 Accelerates Wound Healing | Journal of Investigative Dermatology | 1999 | 255 |
| 15 | Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo | Cancer Letters | 2007 | 254 |
| 16 | Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers | JAMA Neurology | 2019 | 247 |
| 17 | Simian virus-40 large-T antigen binds p53 in human mesotheliomas | Nature Medicine | 1997 | 244 |
| 18 | Induction of IgG3 secretion by interferon gamma: a model for T cell-independent class switching in response to T cell-independent type 2 antigens. | Journal of Experimental Medicine | 1992 | 243 |
| 19 | Multiple molecular targets in cancer chemoprevention by curcumin | AAPS Journal | 2006 | 243 |
| 20 | Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation | Cell | 2022 | 237 |
| 21 | B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching. | Journal of Immunology | 1996 | 236 |
| 22 | Ringlike Structure of the Deinococcus radiodurans Genome: A Key to Radioresistance? | Science | 2003 | 232 |
| 23 | Expression of gene rrg is associated with reversion of NIH 3T3 transformed by LTR-c-H-ras | Science | 1990 | 231 |
| 24 | Protein oxidation: key to bacterial desiccation resistance? | ISME Journal | 2008 | 229 |
| 25 | Development of a New Vaccine for the Prevention of Lassa Fever | PLoS Medicine | 2005 | 223 |
| 26 | Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation | Cytokine and Growth Factor Reviews | 1999 | 216 |
| 27 | B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching | Journal of Immunology | 1996 | 214 |
| 28 | Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59 | Journal of Virology | 1993 | 213 |
| 29 | Extralobar Sequestration with Frequently Associated Congenital Cystic Adenomatoid Malformation, Type 2: Report of 50 Cases | Pediatric and Developmental Pathology | 1999 | 198 |
| 30 | Dendritic Cells Pulsed with Intact Streptococcus pneumoniae Elicit both Protein- and Polysaccharide-specific Immunoglobulin Isotype Responses In Vivo through Distinct Mechanisms | Journal of Experimental Medicine | 2002 | 198 |
| 31 | The Immunoglobulin Class Switch: Beyond “Accessibility” | Immunity | 1997 | 195 |
| 32 | Lysyl oxidase and rrg messenger RNA | Science | 1991 | 192 |
| 33 | TLR2 and TLR4 serve distinct roles in the host immune response againstMycobacterium bovisBCG | Journal of Leukocyte Biology | 2003 | 191 |
| 34 | CYSTIC LUNG DISEASE IN INFANTS AND CHILDREN | Fetal and Pediatric Pathology | 2009 | 173 |
| 35 | Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury | JAMA Psychiatry | 2019 | 170 |
| 36 | Engineering a recombinant Deinococcus radiodurans for organopollutant degradation in radioactive mixed waste environments | Nature Biotechnology | 1998 | 169 |
| 37 | Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells. | Journal of Experimental Medicine | 1993 | 162 |
| 38 | Pathology Competencies for Medical Education and Educational Cases | Academic Pathology | 2017 | 161 |
| 39 | In vivo damage and recA-dependent repair of plasmid and chromosomal DNA in the radiation-resistant bacterium Deinococcus radiodurans | Journal of Bacteriology | 1994 | 158 |
| 40 | Characterisation of interface astroglial scarring in the human brain after blast exposure: a post-mortem case series | Lancet Neurology, The | 2016 | 156 |
| 41 | Dispersion of the ras family of transforming genes to four different chromosomes in man | Nature | 1983 | 155 |
| 42 | Engineering Deinococcus geothermalis for Bioremediation of High-Temperature Radioactive Waste Environments | Applied and Environmental Microbiology | 2003 | 153 |
| 43 | Antiproliferative action of interferon-α requires components of T-cell-receptor signalling | Nature | 1997 | 149 |
| 44 | Activation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA | Nucleic Acids Research | 1989 | 144 |
| 45 | Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice | Journal of Virology | 1990 | 137 |
| 46 | A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens. | Journal of Immunology | 1996 | 136 |
| 47 | Comparative ultrastructure of collagen fibrils in uterine leiomyomas and normal myometrium | Fertility and Sterility | 2004 | 135 |
| 48 | Ablation of triadin causes loss of cardiac Ca 2+ release units, impaired excitation–contraction coupling, and cardiac arrhythmias | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 135 |
| 49 | Inhibition of type 1 diabetes in filaria‐infected non‐obese diabetic mice is associated with a T helper type 2 shift and induction of FoxP3+ regulatory T cells | Immunology | 2009 | 135 |
| 50 | Hemolysin of Uropathogenic Escherichia coli Evokes Extensive Shedding of the Uroepithelium and Hemorrhage in Bladder Tissue within the First 24 Hours after Intraurethral Inoculation of Mice | Infection and Immunity | 2008 | 134 |
