Department of Bioengineering

68(top 1%)

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15.7K(top 1%)

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17.1K

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Top Articles

#	Title	Journal	Year	Citations
1	Association of reactive oxygen species levels and radioresistance in cancer stem cells	Nature	2009	2,232
2	The Development and Application of Optogenetics	Annual Review of Neuroscience	2011	1,567
3	Control, exploitation and tolerance of intracellular noise	Nature	2002	909
4	Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria	Science	2006	694
5	Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia	Science Translational Medicine	2012	630
6	Single-Molecule DNA Sequencing of a Viral Genome	Science	2008	604
7	Dissecting biological “dark matter” with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth	Proceedings of the National Academy of Sciences of the United States of America	2007	552
8	Activation of specific interneurons improves V1 feature selectivity and visual perception	Nature	2012	530
9	Crystal structure of the channelrhodopsin light-gated cation channel	Nature	2012	503
10	Dynamics of Retrieval Strategies for Remote Memories	Cell	2011	481
11	Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines	PLoS ONE	2012	475
12	Understanding the transcriptome through RNA structure	Nature Reviews Genetics	2011	411
13	Single-molecule sequencing of an individual human genome	Nature Biotechnology	2009	394
14	Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding	Nature Biotechnology	2011	377
15	All-Optical Interrogation of Neural Circuits	Journal of Neuroscience	2015	320
16	Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopy	Nature Protocols	2012	312
17	Environmental signal integration by a modular AND gate	Molecular Systems Biology	2007	306
18	Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations	Proceedings of the National Academy of Sciences of the United States of America	2005	304
19	Synthetic Biology: Integrated Gene Circuits	Science	2011	299
20	Synaptic Encoding of Fear Extinction in mPFC-amygdala Circuits	Neuron	2013	298
21	Genome of a Low-Salinity Ammonia-Oxidizing Archaeon Determined by Single-Cell and Metagenomic Analysis	PLoS ONE	2011	287
22	Motifs, modules and games in bacteria	Current Opinion in Microbiology	2003	280
23	Optical activation of lateral amygdala pyramidal cells instructs associative fear learning	Proceedings of the National Academy of Sciences of the United States of America	2010	269
24	Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium	Journal of Cell Biology	2009	253
25	A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins	Neuron	2017	250
26	Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation	Science	2013	238
27	Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis	Nature Biotechnology	2008	215
28	Genome-wide Measurement of RNA Folding Energies	Molecular Cell	2012	192
29	RNA-guided endonuclease provides a therapeutic strategy to cure latent herpesviridae infection	Proceedings of the National Academy of Sciences of the United States of America	2014	188
30	Microfluidic very large scale integration (mVLSI) with integrated micromechanical valves	Lab on A Chip	2012	183
31	The BRAIN Initiative: developing technology to catalyse neuroscience discovery	Philosophical Transactions of the Royal Society B: Biological Sciences	2015	179
32	Hebbian and neuromodulatory mechanisms interact to trigger associative memory formation	Proceedings of the National Academy of Sciences of the United States of America	2014	170
33	Digital PCR provides sensitive and absolute calibration for high throughput sequencing	BMC Genomics	2009	154
34	The evolution of genetic regulatory systems in bacteria	Nature Reviews Genetics	2004	140
35	Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing	Proceedings of the National Academy of Sciences of the United States of America	2005	120
36	Positive Reinforcement Mediated by Midbrain Dopamine Neurons Requires D1 and D2 Receptor Activation in the Nucleus Accumbens	PLoS ONE	2014	119
37	Determinism and stochasticity during maturation of the zebrafish antibody repertoire	Proceedings of the National Academy of Sciences of the United States of America	2011	115
38	Rate of environmental change determines stress response specificity	Proceedings of the National Academy of Sciences of the United States of America	2013	114
39	Deviant effects in molecular reaction pathways	Nature Biotechnology	2006	113
40	From Fluctuations to Phenotypes: The Physiology of Noise	Science's STKE: Signal Transduction Knowledge Environment	2006	108
41	A cell-intrinsic role for TLR2–MYD88 in intestinal and breast epithelia and oncogenesis	Nature Cell Biology	2014	106
42	Cortical and Subcortical Contributions to Short-Term Memory for Orienting Movements	Neuron	2015	106
43	Stretchable and Fully Degradable Semiconductors for Transient Electronics	ACS Central Science	2019	92
44	CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions	Scientific Reports	2017	91
45	Colloidal lenses allow high-temperature single-molecule imaging and improve fluorophore photostability	Nature Nanotechnology	2010	83
46	Fast, cheap and somewhat in control	Genome Biology	2006	82
47	Dynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging-Related Transcriptional Networks	PLoS Genetics	2011	82
48	Partial Genome Assembly for a Candidate Division OP11 Single Cell from an Anoxic Spring (Zodletone Spring, Oklahoma)	Applied and Environmental Microbiology	2011	73
49	Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway	Proceedings of the National Academy of Sciences of the United States of America	2015	62
50	Digital signaling decouples activation probability and population heterogeneity	ELife	2015	60

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