| # | Title | Journal | Year | Citations |
|---|
| 1 | Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Nature | 2006 | 1,777 |
| 2 | Graphical Tools for Network Meta-Analysis in STATA | PLoS ONE | 2013 | 1,714 |
| 3 | Why Most Discovered True Associations Are Inflated | Epidemiology | 2008 | 1,391 |
| 4 | Indirect and mixed‐treatment comparison, network, or multiple‐treatments meta‐analysis: many names, many benefits, many concerns for the next generation evidence synthesis tool | Research Synthesis Methods | 2012 | 1,112 |
| 5 | Evaluating the Quality of Evidence from a Network Meta-Analysis | PLoS ONE | 2014 | 947 |
| 6 | The Effect of Mediterranean Diet on Metabolic Syndrome and its Components | Journal of the American College of Cardiology | 2011 | 917 |
| 7 | Methods to estimate the between‐study variance and its uncertainty in meta‐analysis | Research Synthesis Methods | 2016 | 891 |
| 8 | Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis | Lancet, The | 2012 | 742 |
| 9 | Adiposity and cancer at major anatomical sites: umbrella review of the literature | BMJ: British Medical Journal | 2017 | 539 |
| 10 | Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis | Lancet, The | 2011 | 534 |
| 11 | Accuracy of pedicle screw placement: a systematic review of prospective in vivo studies comparing free hand, fluoroscopy guidance and navigation techniques | European Spine Journal | 2012 | 534 |
| 12 | EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases | Annals of the Rheumatic Diseases | 2011 | 533 |
| 13 | Cancer of unknown primary site | Lancet, The | 2012 | 468 |
| 14 | Breast cancer in young women: an overview | Updates in Surgery | 2017 | 442 |
| 15 | Timing Matters in Hip Fracture Surgery: Patients Operated within 48 Hours Have Better Outcomes. A Meta-Analysis and Meta-Regression of over 190,000 Patients | PLoS ONE | 2012 | 439 |
| 16 | Network meta-analysis: an introduction for clinicians | Internal and Emergency Medicine | 2017 | 439 |
| 17 | Evaluation of inconsistency in networks of interventions | International Journal of Epidemiology | 2013 | 435 |
| 18 | Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review | BMJ, The | 2016 | 415 |
| 19 | STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement | PLoS Medicine | 2009 | 411 |
| 20 | Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome | Arthritis and Rheumatism | 2002 | 410 |
| 21 | A Review of Drug-Induced Hyponatremia | American Journal of Kidney Diseases | 2008 | 382 |
| 22 | Repetitive Transcranial Magnetic Stimulation for the Acute Treatment of Major Depressive Episodes | JAMA Psychiatry | 2017 | 355 |
| 23 | Autonomic Denervation Added to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation | Journal of the American College of Cardiology | 2013 | 340 |
| 24 | Using network meta‐analysis to evaluate the existence of small‐study effects in a network of interventions | Research Synthesis Methods | 2012 | 339 |
| 25 | Comparative efficacy and safety of blood pressure-lowering agents in adults with diabetes and kidney disease: a network meta-analysis | Lancet, The | 2015 | 321 |
| 26 | A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomes | EClinicalMedicine | 2020 | 310 |
| 27 | External validation of new risk prediction models is infrequent and reveals worse prognostic discrimination | Journal of Clinical Epidemiology | 2015 | 290 |
| 28 | Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of severe aortic stenosis: a meta-analysis of randomized trials | European Heart Journal | 2016 | 275 |
| 29 | Percutaneous coronary interventional strategies for treatment of in-stent restenosis: a network meta-analysis | Lancet, The | 2015 | 261 |
| 30 | Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein | Journal of Neuroscience | 2003 | 252 |
| 31 | Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases | PLoS Biology | 2013 | 248 |
| 32 | Allergen immunotherapy for allergic asthma: A systematic review and meta‐analysis | Allergy: European Journal of Allergy and Clinical Immunology | 2017 | 247 |
| 33 | Efficacy of Pharmacotherapy and Psychotherapy for Adult Psychiatric Disorders | JAMA Psychiatry | 2014 | 244 |
| 34 | Get real in individual participant data (IPD) meta‐analysis: a review of the methodology | Research Synthesis Methods | 2015 | 241 |
| 35 | Comparisons of established risk prediction models for cardiovascular disease: systematic review | BMJ, The | 2012 | 238 |
| 36 | Elevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander? | Metabolism: Clinical and Experimental | 2006 | 236 |
| 37 | Effects of Thyroid Dysfunction on Lipid Profile | Open Cardiovascular Medicine Journal | 2011 | 236 |
| 38 | Catastrophizing: a predictive factor for postoperative pain | American Journal of Surgery | 2011 | 228 |
| 39 | Adverse Effects of GLP-1 Receptor Agonists | Review of Diabetic Studies | 2014 | 227 |
| 40 | Selective Reporting Biases in Cancer Prognostic Factor Studies | Journal of the National Cancer Institute | 2005 | 211 |
| 41 | Carcinoma of unknown primary (CUP) | Critical Reviews in Oncology/Hematology | 2009 | 210 |
| 42 | Modernization of an anatomy class: From conceptualization to implementation. A case for integrated multimodal–multidisciplinary teaching | Anatomical Sciences Education | 2012 | 202 |
| 43 | Persistence of Contradicted Claims in the Literature | JAMA - Journal of the American Medical Association | 2007 | 196 |
| 44 | Melanin absorption spectroscopy: new method for noninvasive skin investigation and melanoma detection | Journal of Biomedical Optics | 2008 | 196 |
| 45 | Exploring the Geometry of Treatment Networks | Annals of Internal Medicine | 2008 | 191 |
| 46 | Role of the Fc? receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: A meta-analysis | Arthritis and Rheumatism | 2002 | 179 |
| 47 | Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls | Human Genetics | 2008 | 179 |
| 48 | Phytochemicals in olive‐leaf extracts and their antiproliferative activity against cancer and endothelial cells | Molecular Nutrition and Food Research | 2009 | 178 |
| 49 | JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality | Science Advances | 2021 | 176 |
| 50 | Regeneration and repair of peripheral nerves | Injury | 2005 | 174 |
