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Top Articles

#TitleJournalYearCitations
1A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodentsNature Medicine2015481
2Shape-Controlled Synthesis of Silver Nanoparticles for Plasmonic and Sensing ApplicationsPlasmonics2009364
3Facile Preparation of Nucleoside-5‘-carboxylic AcidsJournal of Organic Chemistry1999330
4Direct Observation of Size-Dependent Optical Enhancement in Single Metal NanoparticlesJournal of the American Chemical Society1998328
5Synthesis of fluorescent D-amino acids and their use for probing peptidoglycan synthesis and bacterial growth in situNature Protocols2015268
6Leptin: Structure, Function and BiologyVitamins and Hormones2005259
7Chemo‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive reviewPhytotherapy Research2019224
8Conformer-dependent proton-transfer reactions of ubiquitin ionsJournal of the American Society for Mass Spectrometry1997219
9Cell shape dynamics during the staphylococcal cell cycleNature Communications2015208
10Vinyl Sulfonate Esters and Vinyl Sulfonamides:  Potent, Irreversible Inhibitors of Cysteine ProteasesJournal of the American Chemical Society1998196
11Studies of mild dehydrogenations in heterocyclic systemsTetrahedron Letters1997193
12A database of 660 peptide ion cross sections: Use of intrinsic size parameters for bona fide predictions of cross sectionsJournal of the American Society for Mass Spectrometry1999191
13Deep penetration of an α-helix into a widened RNA major groove in the HIV-1 rev peptide–RNA aptamer complexNature Structural Biology1996170
14Regio- and Diastereoselective Tandem Rhodium-Catalyzed Allylic Alkylation/Pauson−Khand Annulation ReactionsJournal of the American Chemical Society2001170
15Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesisNature2018149
16Single-Molecule Magnets:  Ligand-Induced Core Distortion and Multiple Jahn−Teller Isomerism in [Mn12O12(O2CMe)8(O2PPh2)8(H2O)4]Journal of the American Chemical Society2001141
17ATP-induced changes in the binding of RNA synthesis termination protein rho to RNAJournal of Molecular Biology1980140
18Characterizing Oligosaccharides Using Injected-Ion Mobility/Mass SpectrometryAnalytical Chemistry1997129
19Total Synthesis of (+)-Amphidinolide KJournal of the American Chemical Society2001127
20A Highly Stereoselective Synthesis of 2-Deoxy-β-glycosides Using 2-Deoxy-2-iodo-glucopyranosyl Acetate DonorsJournal of the American Chemical Society1999124
21Diradical Character of the Cope Rearrangement Transition StateJournal of the American Chemical Society2000121
22Inhibition of parallel flux and augmentation of counter flux shown by transport models not involving a mobile carrierJournal of Theoretical Biology1966119
23Metal-Catalyzed Oxidations of Organic Compounds in the Liquid Phase: A Mechanistic ApproachAdvances in Catalysis1976119
24Evidence for unfolding and refolding of gas-phase cytochrome c ions in a Paul trapJournal of the American Society for Mass Spectrometry2005119
25Anions Stabilize Each Other inside Macrocyclic HostsAngewandte Chemie - International Edition2016115
26Seeding a New Kind of Garden: Synthesis of Architecturally Defined Multimetallic Nanostructures by Seed-Mediated Co-ReductionAccounts of Chemical Research2015104
27Total Synthesis of (+)-Amphidinolide JJournal of the American Chemical Society1998103
28Fluorescent D-amino-acids reveal bi-cellular cell wall modifications important for Bdellovibrio bacteriovorus predationNature Microbiology2017103
29Metalla-enes and Metalla-ynes—from Small Molecules to Infinite PolymersAngewandte Chemie International Edition in English1991101
30Solid-Phase Synthesis of 6-DeoxyoligosaccharidesJournal of the American Chemical Society199699
31Functional Characterization of Core Components of the Bacillus subtilis Cyclic-Di-GMP Signaling PathwayJournal of Bacteriology201396
32Selective reduction of alkynes to cis-alkenes by hydrometallation using [(Ph3P)CuH]6.Tetrahedron Letters199094
33Total Synthesis of (−)-Hennoxazole AJournal of the American Chemical Society199994
34Gas-Phase DNA: Oligothymidine Ion ConformersJournal of the American Chemical Society199786
35Melanocortin signaling in the CNS directly regulates circulating cholesterolNature Neuroscience201086
36Bromine as an oxidant for direct conversion of aldehydes to estersTetrahedron Letters198884
37Measurements of HNO<sub>3</sub> and N<sub>2</sub>O<sub>5</sub> using ion drift-chemical ionization mass spectrometry during the MILAGRO/MCMA-2006 campaignAtmospheric Chemistry and Physics200883
38Fibroblast growth factor 21 night watch: advances and uncertainties in the fieldJournal of Internal Medicine201782
39Conjugate reduction of polyfunctional α,β-unsaturated carbonyl compounds using [(Ph3P)CuH]6. Compatibility with halogen, sulfonate, and γ-oxygen and sulfur substituentsTetrahedron Letters199078
40A new quorum‐sensing system (TprA/PhrA) for Streptococcus pneumoniae D39 that regulates a lantibiotic biosynthesis gene clusterMolecular Microbiology201578
41Aza Diels-Alder reactions in water: Cyclocondensation of C-acyl iminium ions with cyclopentadieneTetrahedron Letters198673
42Lithium perchlorate catalyzed conjugate addition of o-silylated ketene acetals to hindered α,β-unsaturated carbonyl compounds at atmospheric pressureTetrahedron Letters199173
43Chelation controlled addition of allylstannanes to aldehydes in lithium perchlorate-diethyl etherTetrahedron Letters199271
44Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureusMSphere201771
45Influences of Capsule on Cell Shape and Chain Formation of Wild-Type andpcsBMutants of Serotype 2Streptococcus pneumoniaeJournal of Bacteriology200969
46Are single odorous components of a predator sufficient to elicit defensive behaviors in prey species?Frontiers in Neuroscience201567
47Intramolecular variants of aminomethano desilylation: Reactions of in situ generated immonium ions with allylsilanesTetrahedron Letters198666
48New Entries to and New Reactions of Fluorocarbon LigandsJournal of the American Chemical Society199765
49Ascorbic Acid Distribution Patterns in Human Brain.Annals of the New York Academy of Sciences198764
50Incorporation of Ru2(O2C(CH2)6CH3)4into Extended Chains:  Interaction of Ru2(O2C(CH2)6CH3)4with Pyrazine, 4-Cyanopyridine, TCNE, andp-BenzoquinoneInorganic Chemistry199764