| # | Title | Journal | Year | Citations |
|---|
| 1 | Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics | British Journal of Cancer | 1972 | 13,541 |
| 2 | Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples | British Journal of Cancer | 1977 | 7,627 |
| 3 | Histological Grading and Prognosis in Breast Cancer | British Journal of Cancer | 1957 | 2,662 |
| 4 | Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design | British Journal of Cancer | 1976 | 2,163 |
| 5 | The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy | British Journal of Cancer | 1955 | 2,006 |
| 6 | The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis | British Journal of Cancer | 1954 | 1,450 |
| 7 | Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial | British Journal of Cancer | 1999 | 1,327 |
| 8 | Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis | British Journal of Cancer | 2003 | 1,288 |
| 9 | Guidelines for the welfare and use of animals in cancer research | British Journal of Cancer | 2010 | 1,167 |
| 10 | A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse | British Journal of Cancer | 2000 | 1,154 |
| 11 | MicroRNAs in cell proliferation, cell death, and tumorigenesis | British Journal of Cancer | 2006 | 1,121 |
| 12 | The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website | British Journal of Cancer | 2004 | 1,118 |
| 13 | The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis | British Journal of Cancer | 2011 | 1,045 |
| 14 | The clinical course of bone metastases from breast cancer | British Journal of Cancer | 1987 | 997 |
| 15 | REporting recommendations for tumour MARKer prognostic studies (REMARK) | British Journal of Cancer | 2005 | 997 |
| 16 | Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies | British Journal of Cancer | 2005 | 950 |
| 17 | Mechanisms of resistance to immune checkpoint inhibitors | British Journal of Cancer | 2018 | 944 |
| 18 | Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58 515 women with breast cancer and 95 067 women without the disease | British Journal of Cancer | 2002 | 885 |
| 19 | Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis | British Journal of Cancer | 2015 | 880 |
| 20 | Mechanisms of adverse effects of anti-VEGF therapy for cancer | British Journal of Cancer | 2007 | 865 |
| 21 | Who should measure quality of life, the doctor or the patient? | British Journal of Cancer | 1988 | 847 |
| 22 | A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity | British Journal of Cancer | 1987 | 831 |
| 23 | The European mesothelioma epidemic | British Journal of Cancer | 1999 | 817 |
| 24 | Reprogramming of fatty acid metabolism in cancer | British Journal of Cancer | 2020 | 810 |
| 25 | Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study | British Journal of Cancer | 2001 | 790 |
| 26 | Measuring psychological and physical distress in cancer patients: structure and application of the Rotterdam Symptom Checklist | British Journal of Cancer | 1990 | 789 |
| 27 | The Production of Malignant Primary Hepatic Tumours in the Rat by Feeding Dimethylnitrosamine | British Journal of Cancer | 1956 | 788 |
| 28 | Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County | British Journal of Cancer | 1991 | 788 |
| 29 | High levels of untreated distress and fatigue in cancer patients | British Journal of Cancer | 2004 | 786 |
| 30 | The Spread of Rectal Cancer and its Effect on Prognosis | British Journal of Cancer | 1958 | 774 |
| 31 | The benefits and harms of breast cancer screening: an independent review | British Journal of Cancer | 2013 | 767 |
| 32 | Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12 155 patients | British Journal of Cancer | 2007 | 763 |
| 33 | Morphine and alternative opioids in cancer pain: the EAPC recommendations | British Journal of Cancer | 2001 | 759 |
| 34 | Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies | British Journal of Cancer | 2006 | 759 |
| 35 | Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer | British Journal of Cancer | 1995 | 753 |
| 36 | Cancer heterogeneity: implications for targeted therapeutics | British Journal of Cancer | 2013 | 753 |
| 37 | Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement | British Journal of Cancer | 2015 | 752 |
| 38 | High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up | British Journal of Cancer | 2006 | 727 |
| 39 | Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials | British Journal of Cancer | 2001 | 723 |
| 40 | Dynamics of Tumor Growth | British Journal of Cancer | 1964 | 720 |
| 41 | Cytokines in clinical cancer immunotherapy | British Journal of Cancer | 2019 | 720 |
| 42 | Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy | British Journal of Cancer | 2007 | 711 |
| 43 | The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour | British Journal of Cancer | 1968 | 709 |
| 44 | Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer | British Journal of Cancer | 2019 | 702 |
| 45 | Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer | British Journal of Cancer | 2013 | 687 |
| 46 | Information needs of patients with cancer: results from a large study in UK cancer centres | British Journal of Cancer | 2001 | 684 |
| 47 | Long noncoding RNAs and the genetics of cancer | British Journal of Cancer | 2013 | 676 |
| 48 | Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review | British Journal of Cancer | 2015 | 676 |
| 49 | Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water | British Journal of Cancer | 1992 | 672 |
| 50 | Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer | British Journal of Cancer | 2009 | 661 |
