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Cell Chemical Biology
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top-articles
Cell Chemical Biology
6.9
(top 5%)
impact factor
1.2K
(top 20%)
papers
36.6K
(top 10%)
citations
84
(top 10%)
h
-index
7.1
(top 5%)
impact factor
1.5K
all documents
42.3K
doc citations
129
(top 10%)
g
-index
Top Articles
#
Title
Journal
Year
Citations
1
Targeting Metabolism for Cancer Therapy
Cell Chemical Biology
2017
677
2
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
Cell Chemical Biology
2018
556
3
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State
Cell Chemical Biology
2019
556
4
Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
Cell Chemical Biology
2017
424
5
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study
Cell Chemical Biology
2018
422
6
Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model
Cell Chemical Biology
2019
399
7
Autophagy-Dependent Ferroptosis: Machinery and Regulation
Cell Chemical Biology
2020
399
8
Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery
Cell Chemical Biology
2017
388
9
A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
Cell Chemical Biology
2018
313
10
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Cell Chemical Biology
2017
286
11
N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production
Cell Chemical Biology
2018
270
12
Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control
Cell Chemical Biology
2017
264
13
Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals
Cell Chemical Biology
2016
263
14
The Emerging Role of RNA as a Therapeutic Target for Small Molecules
Cell Chemical Biology
2016
249
15
Hedgehog Signaling: From Basic Biology to Cancer Therapy
Cell Chemical Biology
2017
242
16
PROTACs: An Emerging Therapeutic Modality in Precision Medicine
Cell Chemical Biology
2020
242
17
New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products
Cell Chemical Biology
2016
241
18
Nucleic Acid Modifications in Regulation of Gene Expression
Cell Chemical Biology
2016
219
19
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Cell Chemical Biology
2019
219
20
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity
Cell Chemical Biology
2016
217
21
Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis
Cell Chemical Biology
2020
215
22
The Chemistry and Biology of Ferroptosis
Cell Chemical Biology
2020
204
23
A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical Application
Cell Chemical Biology
2016
200
24
Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement
Cell Chemical Biology
2018
197
25
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
Cell Chemical Biology
2019
188
26
RNA-DNA Triplex Formation by Long Noncoding RNAs
Cell Chemical Biology
2016
183
27
Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
Cell Chemical Biology
2020
182
28
Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery
Cell Chemical Biology
2018
176
29
Regulation of Virulence in Staphylococcus aureus : Molecular Mechanisms and Remaining Puzzles
Cell Chemical Biology
2016
166
30
Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic Opportunities
Cell Chemical Biology
2018
160
31
The Rheumatoid Arthritis-Associated Citrullinome
Cell Chemical Biology
2018
158
32
Symbiont-Derived Antimicrobials Contribute to the Control of the Lepidopteran Gut Microbiota
Cell Chemical Biology
2017
157
33
Unmasking Fucosylation: from Cell Adhesion to Immune System Regulation and Diseases
Cell Chemical Biology
2018
156
34
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials
Cell Chemical Biology
2016
154
35
Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
Cell Chemical Biology
2018
154
36
Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
Cell Chemical Biology
2019
151
37
Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7
Cell Chemical Biology
2017
149
38
Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation
Cell Chemical Biology
2016
147
39
Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin
Cell Chemical Biology
2017
145
40
Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis
Cell Chemical Biology
2020
144
41
APOBEC Enzymes as Targets for Virus and Cancer Therapy
Cell Chemical Biology
2018
137
42
Ferroptosis and Necroptosis in the Kidney
Cell Chemical Biology
2020
137
43
Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids
Cell Chemical Biology
2019
134
44
EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
Cell Chemical Biology
2020
131
45
Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction
Cell Chemical Biology
2019
129
46
Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease
Cell Chemical Biology
2017
128
47
MemBright: A Family of Fluorescent Membrane Probes for Advanced Cellular Imaging and Neuroscience
Cell Chemical Biology
2019
128
48
DNA Charge Transport: from Chemical Principles to the Cell
Cell Chemical Biology
2016
127
49
Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
Cell Chemical Biology
2020
127
50
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions
Cell Chemical Biology
2018
124
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