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Top Articles

#TitleJournalYearCitations
1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsNature Cell Biology200710,558
2AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Nature Cell Biology20115,447
3Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkersNature Cell Biology20084,285
4The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1Nature Cell Biology20083,455
5The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expressionNature Cell Biology20003,208
6TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signallingNature Cell Biology20022,667
7Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisNature Cell Biology20002,487
8AP-1 as a regulator of cell life and deathNature Cell Biology20022,448
9Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communicationNature Cell Biology20192,408
10Dynamic interaction of BiP and ER stress transducers in the unfolded-protein responseNature Cell Biology20002,397
11MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteinsNature Cell Biology20112,395
12PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1Nature Cell Biology20102,360
13The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cellsNature Cell Biology20002,355
14The AMPK signalling pathway coordinates cell growth, autophagy and metabolismNature Cell Biology20112,345
15Many roads to maturity: microRNA biogenesis pathways and their regulationNature Cell Biology20092,328
16Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in miceNature Cell Biology20142,241
17Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressNature Cell Biology20112,171
18Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivoNature Cell Biology20012,153
19Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liverNature Cell Biology20152,064
20Rab27a and Rab27b control different steps of the exosome secretion pathwayNature Cell Biology20101,992
21Autophagosome formation: core machinery and adaptationsNature Cell Biology20071,938
22The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1Nature Cell Biology20101,933
23Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substratesNature Cell Biology20011,924
24Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitiveNature Cell Biology20041,873
25Eaten alive: a history of macroautophagyNature Cell Biology20101,839
26α-Synuclein is phosphorylated in synucleinopathy lesionsNature Cell Biology20021,739
27Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretionNature Cell Biology20091,734
28Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cellsNature Cell Biology20081,688
29Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translationNature Cell Biology20181,650
30Wnt activity defines colon cancer stem cells and is regulated by the microenvironmentNature Cell Biology20101,623
31A complex secretory program orchestrated by the inflammasome controls paracrine senescenceNature Cell Biology20131,566
32The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAsNature Cell Biology20091,547
33Causes and consequences of replication stressNature Cell Biology20141,545
34Transmission and spreading of tauopathy in transgenic mouse brainNature Cell Biology20091,515
35Isolation of multipotent adult stem cells from the dermis of mammalian skinNature Cell Biology20011,503
36Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transitionNature Cell Biology20041,459
37Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau proteinNature Cell Biology20001,423
38During autophagy mitochondria elongate, are spared from degradation and sustain cell viabilityNature Cell Biology20111,421
39p53 mutations in cancerNature Cell Biology20131,421
40SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27Nature Cell Biology19991,405
41Syndecan–syntenin–ALIX regulates the biogenesis of exosomesNature Cell Biology20121,388
42Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosomeNature Cell Biology20001,358
43Activation of the interferon system by short-interfering RNAsNature Cell Biology20031,354
44Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathwaysNature Cell Biology20011,331
45Protein S-nitrosylation: a physiological signal for neuronal nitric oxideNature Cell Biology20011,321
46Organelle-specific initiation of cell death pathwaysNature Cell Biology20011,320
47ER-stress-induced transcriptional regulation increases protein synthesis leading to cell deathNature Cell Biology20131,315
48Autophagy in mammalian development and differentiationNature Cell Biology20101,313
49Induction of autophagy by spermidine promotes longevityNature Cell Biology20091,302
50Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesisNature Cell Biology20101,299