| # | Title | Journal | Year | Citations |
|---|
| 1 | Population Structure and Eigenanalysis | PLoS Genetics | 2006 | 4,163 |
| 2 | A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies | PLoS Genetics | 2009 | 3,526 |
| 3 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
| 4 | Inference of Population Splits and Mixtures from Genome-Wide Allele Frequency Data | PLoS Genetics | 2012 | 1,997 |
| 5 | Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis | PLoS Genetics | 2007 | 1,599 |
| 6 | Cell-Type Specific Features of Circular RNA Expression | PLoS Genetics | 2013 | 1,544 |
| 7 | Inferring the Joint Demographic History of Multiple Populations from Multidimensional SNP Frequency Data | PLoS Genetics | 2009 | 1,522 |
| 8 | Detecting Individual Sites Subject to Episodic Diversifying Selection | PLoS Genetics | 2012 | 1,455 |
| 9 | Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits | PLoS Genetics | 2007 | 1,446 |
| 10 | Power and Predictive Accuracy of Polygenic Risk Scores | PLoS Genetics | 2013 | 1,238 |
| 11 | Population Genomics of Parallel Adaptation in Threespine Stickleback using Sequenced RAD Tags | PLoS Genetics | 2010 | 1,219 |
| 12 | Robust Demographic Inference from Genomic and SNP Data | PLoS Genetics | 2013 | 1,185 |
| 13 | Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS | PLoS Genetics | 2010 | 1,161 |
| 14 | A Molecular Phylogeny of Living Primates | PLoS Genetics | 2011 | 1,130 |
| 15 | Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies | PLoS Genetics | 2016 | 1,095 |
| 16 | Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths | PLoS Genetics | 2009 | 1,005 |
| 17 | A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic | PLoS Genetics | 2009 | 989 |
| 18 | Inference of Population Structure using Dense Haplotype Data | PLoS Genetics | 2012 | 983 |
| 19 | Orienting the causal relationship between imprecisely measured traits using GWAS summary data | PLoS Genetics | 2017 | 969 |
| 20 | Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context | PLoS Genetics | 2009 | 931 |
| 21 | Repetitive Elements May Comprise Over Two-Thirds of the Human Genome | PLoS Genetics | 2011 | 907 |
| 22 | Genomic Analysis of the Necrotrophic Fungal Pathogens Sclerotinia sclerotiorum and Botrytis cinerea | PLoS Genetics | 2011 | 902 |
| 23 | p53 Activation by Knockdown Technologies | PLoS Genetics | 2007 | 893 |
| 24 | Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays | PLoS Genetics | 2008 | 892 |
| 25 | Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains | PLoS Genetics | 2008 | 878 |
| 26 | Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes | PLoS Genetics | 2013 | 844 |
| 27 | Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits | PLoS Genetics | 2008 | 823 |
| 28 | Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function | PLoS Genetics | 2005 | 815 |
| 29 | Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits | PLoS Genetics | 2011 | 796 |
| 30 | Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk | PLoS Genetics | 2010 | 789 |
| 31 | Exploring Microbial Diversity and Taxonomy Using SSU rRNA Hypervariable Tag Sequencing | PLoS Genetics | 2008 | 779 |
| 32 | The Population Genetics of dN/dS | PLoS Genetics | 2008 | 775 |
| 33 | Discordance of Species Trees with Their Most Likely Gene Trees | PLoS Genetics | 2006 | 761 |
| 34 | Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain | PLoS Genetics | 2010 | 722 |
| 35 | Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair | PLoS Genetics | 2008 | 708 |
| 36 | A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation | PLoS Genetics | 2009 | 700 |
| 37 | Polygenic Modeling with Bayesian Sparse Linear Mixed Models | PLoS Genetics | 2013 | 686 |
| 38 | Ancient Protostome Origin of Chemosensory Ionotropic Glutamate Receptors and the Evolution of Insect Taste and Olfaction | PLoS Genetics | 2010 | 680 |
| 39 | Comparative Genomics of Multidrug Resistance in Acinetobacter baumannii | PLoS Genetics | 2006 | 677 |
| 40 | Assessing the Impact of Transgenerational Epigenetic Variation on Complex Traits | PLoS Genetics | 2009 | 669 |
| 41 | Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes | PLoS Genetics | 2006 | 661 |
| 42 | Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum | PLoS Genetics | 2008 | 660 |
| 43 | A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci | PLoS Genetics | 2009 | 656 |
| 44 | Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB | PLoS Genetics | 2013 | 655 |
| 45 | Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs | PLoS Genetics | 2013 | 655 |
| 46 | A Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs | PLoS Genetics | 2007 | 654 |
| 47 | Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System | PLoS Genetics | 2011 | 650 |
| 48 | A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans | PLoS Genetics | 2008 | 639 |
| 49 | The Genetic Signatures of Noncoding RNAs | PLoS Genetics | 2009 | 639 |
| 50 | Why Do Hubs Tend to Be Essential in Protein Networks? | PLoS Genetics | 2006 | 634 |
