29.0(top 0.1%)
impact factor
9.3K(top 2%)
papers
1.3M(top 1%)
citations
536(top 0.1%)
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31.3(top 1%)
impact factor
18.5K
all documents
1.4M
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918(top 0.1%)
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Top Articles

#TitleJournalYearCitations
1Full-length transcriptome assembly from RNA-Seq data without a reference genomeNature Biotechnology201117,264
2Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationNature Biotechnology201013,805
3MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationNature Biotechnology200812,966
4Integrative genomics viewerNature Biotechnology201111,708
5Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2Nature Biotechnology201911,167
6Integrating single-cell transcriptomic data across different conditions, technologies, and speciesNature Biotechnology20188,878
7StringTie enables improved reconstruction of a transcriptome from RNA-seq readsNature Biotechnology20158,385
8Predictive functional profiling of microbial communities using 16S rRNA marker gene sequencesNature Biotechnology20138,049
9Near-optimal probabilistic RNA-seq quantificationNature Biotechnology20167,322
10Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotypeNature Biotechnology20196,567
113D bioprinting of tissues and organsNature Biotechnology20145,158
12Principles of nanoparticle design for overcoming biological barriers to drug deliveryNature Biotechnology20154,868
13Quantitative analysis of complex protein mixtures using isotope-coded affinity tagsNature Biotechnology19994,673
14The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cellsNature Biotechnology20144,652
15Large-scale analysis of the yeast proteome by multidimensional protein identification technologyNature Biotechnology20014,540
16In vivo cancer targeting and imaging with semiconductor quantum dotsNature Biotechnology20044,460
17Spatial reconstruction of single-cell gene expression dataNature Biotechnology20154,254
18Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent proteinNature Biotechnology20044,135
19Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineeringNature Biotechnology20054,068
20Molecular Beacons: Probes that Fluoresce upon HybridizationNature Biotechnology19963,956
21DNA targeting specificity of RNA-guided Cas9 nucleasesNature Biotechnology20133,953
22Sensitive detection of somatic point mutations in impure and heterogeneous cancer samplesNature Biotechnology20133,934
23Renal clearance of quantum dotsNature Biotechnology20073,789
24GREAT improves functional interpretation of cis-regulatory regionsNature Biotechnology20103,789
25Next-generation DNA sequencingNature Biotechnology20083,609
26Delivery of siRNA to the mouse brain by systemic injection of targeted exosomesNature Biotechnology20113,595
27Nonlinear magic: multiphoton microscopy in the biosciencesNature Biotechnology20033,524
28Antimicrobial and host-defense peptides as new anti-infective therapeutic strategiesNature Biotechnology20063,490
29A clearer vision for in vivo imagingNature Biotechnology20013,393
30SignalP 5.0 improves signal peptide predictions using deep neural networksNature Biotechnology20193,317
31Differential analysis of gene regulation at transcript resolution with RNA-seqNature Biotechnology20133,256
32Dimensionality reduction for visualizing single-cell data using UMAPNature Biotechnology20193,254
33What is flux balance analysis?Nature Biotechnology20103,233
34Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9Nature Biotechnology20163,168
35An economic method for the fluorescent labeling of PCR fragmentsNature Biotechnology20003,083
36Fabrication of novel biomaterials through molecular self-assemblyNature Biotechnology20033,048
37Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signalingNature Biotechnology20093,047
38Expression monitoring by hybridization to high-density oligonucleotide arraysNature Biotechnology19963,041
39The use of nanocrystals in biological detectionNature Biotechnology20042,849
40Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular NetworkingNature Biotechnology20162,802
41A cross-platform toolkit for mass spectrometry and proteomicsNature Biotechnology20122,794
42High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cellsNature Biotechnology20132,754
43Assembly of long, error-prone reads using repeat graphsNature Biotechnology20192,730
44What is a support vector machine?Nature Biotechnology20062,669
45CRISPR-Cas systems for editing, regulating and targeting genomesNature Biotechnology20142,648
46Efficient genome editing in zebrafish using a CRISPR-Cas systemNature Biotechnology20132,638
47PICRUSt2 for prediction of metagenome functionsNature Biotechnology20202,621
48A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of lifeNature Biotechnology20182,615
49Generation of induced pluripotent stem cells without Myc from mouse and human fibroblastsNature Biotechnology20082,583
50Embryonic stem cell lines from human blastocysts: somatic differentiation in vitroNature Biotechnology20002,554