| # | Title | Journal | Year | Citations |
|---|
| 1 | Electric Field Effect in Atomically Thin Carbon Films | Science | 2004 | 56,177 |
| 2 | Optimization by Simulated Annealing | Science | 1983 | 35,496 |
| 3 | Emergence of Scaling in Random Networks | Science | 1999 | 28,383 |
| 4 | Judgment under Uncertainty: Heuristics and Biases | Science | 1974 | 23,858 |
| 5 | The Tragedy of the Commons | Science | 1968 | 20,183 |
| 6 | Multilineage Potential of Adult Human Mesenchymal Stem Cells | Science | 1999 | 18,830 |
| 7 | Measurement of the Elastic Properties and Intrinsic Strength of Monolayer Graphene | Science | 2008 | 17,513 |
| 8 | Reducing the Dimensionality of Data with Neural Networks | Science | 2006 | 14,686 |
| 9 | Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase | Science | 1988 | 13,840 |
| 10 | Embryonic Stem Cell Lines Derived from Human Blastocysts | Science | 1998 | 13,539 |
| 11 | The Framing of Decisions and the Psychology of Choice | Science | 1981 | 13,316 |
| 12 | Optical Coherence Tomography | Science | 1991 | 13,009 |
| 13 | A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity | Science | 2012 | 12,811 |
| 14 | Multiplex Genome Engineering Using CRISPR/Cas Systems | Science | 2013 | 12,725 |
| 15 | The Sequence of the Human Genome | Science | 2001 | 12,623 |
| 16 | Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase | Science | 1988 | 12,204 |
| 17 | Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation | Science | 2009 | 12,186 |
| 18 | Graphene: Status and Prospects | Science | 2009 | 12,120 |
| 19 | The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics | Science | 2002 | 12,113 |
| 20 | Nonlinear Dimensionality Reduction by Locally Linear Embedding | Science | 2000 | 12,086 |
| 21 | The Chemistry and Applications of Metal-Organic Frameworks | Science | 2013 | 12,032 |
| 22 | Electrical Energy Storage for the Grid: A Battery of Choices | Science | 2011 | 11,724 |
| 23 | Visible-Light Photocatalysis in Nitrogen-Doped Titanium Oxides | Science | 2001 | 11,440 |
| 24 | On the Origin of Cancer Cells | Science | 1956 | 11,358 |
| 25 | Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores | Science | 1998 | 10,937 |
| 26 | A Global Geometric Framework for Nonlinear Dimensionality Reduction | Science | 2000 | 10,827 |
| 27 | Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene | Science | 1987 | 10,804 |
| 28 | Tissue-based map of the human proteome | Science | 2015 | 10,802 |
| 29 | Semiconductor Clusters, Nanocrystals, and Quantum Dots | Science | 1996 | 10,633 |
| 30 | Bacterial Biofilms: A Common Cause of Persistent Infections | Science | 1999 | 10,329 |
| 31 | Spintronics: A Spin-Based Electronics Vision for the Future | Science | 2001 | 10,189 |
| 32 | The Evolution of Cooperation | Science | 1981 | 10,174 |
| 33 | Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring | Science | 1999 | 10,140 |
| 34 | Large-Area Synthesis of High-Quality and Uniform Graphene Films on Copper Foils | Science | 2009 | 10,000 |
| 35 | Polymer Photovoltaic Cells: Enhanced Efficiencies via a Network of Internal Donor-Acceptor Heterojunctions | Science | 1995 | 9,591 |
| 36 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering | Science | 1997 | 9,549 |
| 37 | Pain Mechanisms: A New Theory | Science | 1965 | 9,521 |
| 38 | Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells | Science | 2007 | 9,459 |
| 39 | Fuzzy Nanoassemblies: Toward Layered Polymeric Multicomposites | Science | 1997 | 9,458 |
| 40 | Carbon Nanotubes--the Route Toward Applications | Science | 2002 | 9,458 |
| 41 | Global Consequences of Land Use | Science | 2005 | 9,451 |
| 42 | Tissue Engineering | Science | 1993 | 9,341 |
| 43 | Efficient Hybrid Solar Cells Based on Meso-Superstructured Organometal Halide Perovskites | Science | 2012 | 9,249 |
| 44 | Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase | Science | 1990 | 9,174 |
| 45 | Two-Photon Laser Scanning Fluorescence Microscopy | Science | 1990 | 9,113 |
| 46 | Neighborhoods and Violent Crime: A Multilevel Study of Collective Efficacy | Science | 1997 | 9,112 |
| 47 | The Need for a New Medical Model: A Challenge for Biomedicine | Science | 1977 | 9,066 |
| 48 | EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy | Science | 2004 | 9,038 |
| 49 | Mussel-Inspired Surface Chemistry for Multifunctional Coatings | Science | 2007 | 9,012 |
| 50 | Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia | Science | 1985 | 8,828 |
