| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 3.8K |
| Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries | JAMA - Journal of the American Medical Association | 2016 | 2.1K |
| Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria | Alzheimer's and Dementia | 2016 | 832 |
| STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration | BMJ Open | 2016 | 789 |
| Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages | Blood | 2016 | 675 |
| Iron deficiency anaemia | Lancet, The | 2016 | 611 |
| European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update | Annals of the Rheumatic Diseases | 2016 | 611 |
| Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination | Nature Reviews Clinical Oncology | 2016 | 591 |
| Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit | New England Journal of Medicine | 2016 | 549 |
| Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper | Annals of Oncology | 2016 | 548 |
| The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation | Annals of the Rheumatic Diseases | 2016 | 540 |
| Improved Automated Detection of Diabetic Retinopathy on a Publicly Available Dataset Through Integration of Deep Learning | | 2016 | 478 |
| Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 473 |
| Metabolic Control of Longevity | Cell | 2016 | 429 |
| Physiological changes in pregnancy | Cardiovascular Journal of Africa | 2016 | 427 |
| Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease | Gut | 2016 | 396 |
| Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management | European Respiratory Journal | 2016 | 396 |
| Comparative Short-term Benefits of Laparoscopic Liver Resection: 9000 Cases and Climbing | Annals of Surgery | 2016 | 396 |
| Clinical trial of blood-brain barrier disruption by pulsed ultrasound | Science Translational Medicine | 2016 | 377 |
| Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects | Immunity | 2016 | 376 |
| The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease | Journal of Crohn's and Colitis | 2016 | 354 |
| Calcific aortic stenosis | Nature Reviews Disease Primers | 2016 | 341 |
| Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy | Annals of Oncology | 2016 | 335 |
| Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 328 |
| Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes | Nature Microbiology | 2016 | 327 |
