| # | Title | Journal | Year | Citations |
|---|
| 1 | The complete genome sequence of the Gram-positive bacterium Bacillus subtilis | Nature | 1997 | 3,519 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Bandgap opening in graphene induced by patterned hydrogen adsorption | Nature Materials | 2010 | 1,344 |
| 4 | Genome-wide analysis of mammalian promoter architecture and evolution | Nature Genetics | 2006 | 1,201 |
| 5 | Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis | Nature Cell Biology | 2002 | 636 |
| 6 | Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain | FEBS Letters | 1995 | 634 |
| 7 | Mutant p53 as a guardian of the cancer cell | Cell Death and Differentiation | 2019 | 523 |
| 8 | Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1 | EMBO Journal | 1999 | 463 |
| 9 | TDP‐43 is recruited to stress granules in conditions of oxidative insult | Journal of Neurochemistry | 2009 | 435 |
| 10 | The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme | Antioxidants and Redox Signaling | 2009 | 424 |
| 11 | The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults | Nature | 2002 | 390 |
| 12 | Crossvalidation of anthropometry against magnetic resonance imaging for the assessment of visceral and subcutaneous adipose tissue in children | International Journal of Obesity | 2006 | 384 |
| 13 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 14 | Familial dilated cardiomyopathy | Journal of the American College of Cardiology | 1999 | 304 |
| 15 | Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate | Cancer | 2001 | 291 |
| 16 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity | Nature Genetics | 2018 | 286 |
| 17 | A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates | Gene | 1992 | 260 |
| 18 | Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. | EMBO Journal | 1995 | 242 |
| 19 | Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 240 |
| 20 | Biological Characterization of Two Novel Cathelicidin-derived Peptides and Identification of Structural Requirements for Their Antimicrobial and Cell Lytic Activities | Journal of Biological Chemistry | 1996 | 236 |
| 21 | p65/RelA Modulates BECN1 Transcription and Autophagy | Molecular and Cellular Biology | 2009 | 235 |
| 22 | TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells | Journal of Biological Chemistry | 2012 | 233 |
| 23 | Microcavity Polariton Splitting of Intersubband Transitions | Physical Review Letters | 2003 | 226 |
| 24 | p53-family proteins and their regulators: hubs and spokes in tumor suppression | Cell Death and Differentiation | 2010 | 196 |
| 25 | Incidence and natural course of fatty liver in the general population: The Dionysos study | Hepatology | 2007 | 192 |
| 26 | TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis | Acta Neuropathologica | 2020 | 186 |
| 27 | Germline CDH1 deletions in hereditary diffuse gastric cancer families | Human Molecular Genetics | 2009 | 185 |
| 28 | Fine mapping of a replication origin of human DNA. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 180 |
| 29 | Polysaccharides from hot water extracts of roasted Coffea arabica beans: isolation and characterization | Carbohydrate Polymers | 1999 | 177 |
| 30 | Size-dependent oxidation in iron/iron oxide core-shell nanoparticles | Physical Review B | 2003 | 175 |
| 31 | Molecular basis of bilirubin-induced neurotoxicity | Trends in Molecular Medicine | 2004 | 171 |
| 32 | Bisphosphonate-associated jawbone osteonecrosis: a correlation between imaging techniques and histopathology | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics | 2008 | 170 |
| 33 | Predictors of non-alcoholic fatty liver disease in obese children | European Journal of Clinical Nutrition | 2007 | 165 |
| 34 | Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A | Oncogene | 2005 | 157 |
| 35 | YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins | EMBO Reports | 2016 | 154 |
| 36 | Potassium and Sodium Binding to the Outer Mouth of the K+ Channel | Biochemistry | 1999 | 146 |
| 37 | TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation | IUBMB Life | 2012 | 144 |
| 38 | Inhibition of matrix-proteases by polyphenols: chemical insights for anti-inflammatory and anti-invasion drug design | Biochemical Pharmacology | 2002 | 142 |
| 39 | Transcriptional Activation of the Cyclin A Gene by the Architectural Transcription Factor HMGA2 | Molecular and Cellular Biology | 2003 | 140 |
| 40 | Hydrothermally Stable, Conformal, Sulfated Zirconia Monolayer Catalysts for Glucose Conversion to 5-HMF | ACS Catalysis | 2015 | 137 |
| 41 | Mutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP | Molecular Cell | 2014 | 136 |
| 42 | Biotechnology and the bioeconomy—Towards inclusive and sustainable industrial development | New Biotechnology | 2018 | 131 |
| 43 | Prolyl‐isomerase Pin1 controls normal and cancer stem cells of the breast | EMBO Molecular Medicine | 2014 | 130 |
| 44 | Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ | Oncogene | 2017 | 123 |
| 45 | Biodegradable plastics: a solution or a challenge? | Journal of Cleaner Production | 2003 | 111 |
| 46 | Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer | Cell Cycle | 2013 | 109 |
| 47 | Functionalized gold nanoparticles: a detailed in vivo multimodal microscopic brain distribution study | Nanoscale | 2010 | 108 |
| 48 | Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA | FEBS Letters | 1994 | 105 |
| 49 | An Analysis of Finite Volume, Finite Element, and Finite Difference Methods Using Some Concepts from Algebraic Topology | Journal of Computational Physics | 1997 | 100 |
| 50 | cDNA sequences of three sheep myeloid cathelicidins | FEBS Letters | 1995 | 98 |
