| Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors | Science | 2018 | 2.2K |
| Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome | New England Journal of Medicine | 2018 | 1.3K |
| International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study | Lancet, The | 2018 | 910 |
| GW170817: Measurements of Neutron Star Radii and Equation of State | Physical Review Letters | 2018 | 867 |
| Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA | Living Reviews in Relativity | 2018 | 543 |
| International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity | Journal of Clinical Immunology | 2018 | 510 |
| Mitochondrial metabolism and cancer | Cell Research | 2018 | 462 |
| Spermidine in health and disease | Science | 2018 | 358 |
| The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | Journal of Clinical Immunology | 2018 | 345 |
| The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies | Science | 2018 | 341 |
| Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 323 |
| A comparison of methods to assess cell mechanical properties | Nature Methods | 2018 | 265 |
| Phase III, randomised trial of avelumab versus physician's choice of chemotherapy as third-line treatment of patients with advanced gastric or gastro-oesophageal junction cancer: primary analysis of JAVELIN Gastric 300 | Annals of Oncology | 2018 | 241 |
| The polyol process: a unique method for easy access to metal nanoparticles with tailored sizes, shapes and compositions | Chemical Society Reviews | 2018 | 237 |
| Transplantation of Human Embryonic Stem Cell-Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction | Journal of the American College of Cardiology | 2018 | 235 |
| AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System X Activity | Current Biology | 2018 | 234 |
| Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing | Nature Reviews Drug Discovery | 2018 | 232 |
| Targeted therapy in patients with PIK3CA-related overgrowth syndrome | Nature | 2018 | 225 |
| The hygiene hypothesis in autoimmunity: the role of pathogens and commensals | Nature Reviews Immunology | 2018 | 218 |
| Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2) | Lancet, The | 2018 | 218 |
| Evolution of Metastases in Space and Time under Immune Selection | Cell | 2018 | 207 |
| Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis | Cell Host and Microbe | 2018 | 206 |
| Zika, Chikungunya, and Other Emerging Vector-Borne Viral Diseases | Annual Review of Medicine | 2018 | 189 |
| Role of direct oral anticoagulants in the treatment of cancer-associated venous thromboembolism: guidance from the SSC of the ISTH | Journal of Thrombosis and Haemostasis | 2018 | 189 |
| Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression | Molecular Psychiatry | 2018 | 188 |
