| # | Title | Journal | Year | Citations |
|---|
| 1 | Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Start Denver Model | Pediatrics | 2010 | 1,921 |
| 2 | Comorbid Psychiatric Disorders in Children with Autism: Interview Development and Rates of Disorders | Journal of Autism and Developmental Disorders | 2006 | 1,336 |
| 3 | The complete sequence of a human genome | Science | 2022 | 1,222 |
| 4 | Penetrance of the Fragile X–Associated Tremor/Ataxia Syndrome in a Premutation Carrier Population | JAMA - Journal of the American Medical Association | 2004 | 571 |
| 5 | Psychedelics Promote Structural and Functional Neural Plasticity | Cell Reports | 2018 | 566 |
| 6 | A prospective study of the emergence of early behavioral signs of autism | Journal of the American Academy of Child and Adolescent Psychiatry | 2010 | 520 |
| 7 | Engaging neuroscience to advance translational research in brain barrier biology | Nature Reviews Neuroscience | 2011 | 508 |
| 8 | Structural brain variation and general intelligence | NeuroImage | 2004 | 493 |
| 9 | Fragile X syndrome | Nature Reviews Disease Primers | 2017 | 490 |
| 10 | Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases | Nature Genetics | 2017 | 443 |
| 11 | Use of tissue water as a concentration reference for proton spectroscopic imaging | Magnetic Resonance in Medicine | 2006 | 430 |
| 12 | Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans | Journal of Cerebral Blood Flow and Metabolism | 2014 | 423 |
| 13 | 22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia | Nature Reviews Neuroscience | 2010 | 417 |
| 14 | Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders | Genetics in Medicine | 2019 | 378 |
| 15 | A pilot open label, single dose trial of fenobam in adults with fragile X syndrome | Journal of Medical Genetics | 2009 | 354 |
| 16 | Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke | Frontiers in Cellular Neuroscience | 2016 | 336 |
| 17 | Source‐based morphometry: The use of independent component analysis to identify gray matter differences with application to schizophrenia | Human Brain Mapping | 2009 | 311 |
| 18 | The Gut Microbiota and Autism Spectrum Disorders | Frontiers in Cellular Neuroscience | 2017 | 311 |
| 19 | Fragile X‐associated tremor/ataxia syndrome: Clinical features, genetics, and testing guidelines | Movement Disorders | 2007 | 306 |
| 20 | Gene Expression in Blood Changes Rapidly in Neutrophils and Monocytes after Ischemic Stroke in Humans: A Microarray Study | Journal of Cerebral Blood Flow and Metabolism | 2006 | 298 |
| 21 | Gaze behavior and affect at 6 months: predicting clinical outcomes and language development in typically developing infants and infants at risk for autism | Developmental Science | 2009 | 296 |
| 22 | Diagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2015 | 277 |
| 23 | Behavioral Treatments in Autism Spectrum Disorder: What Do We Know? | Annual Review of Clinical Psychology | 2010 | 276 |
| 24 | What are infant siblings teaching us about autism in infancy? | Autism Research | 2009 | 265 |
| 25 | Autism Treatment in the First Year of Life: A Pilot Study of Infant Start, a Parent-Implemented Intervention for Symptomatic Infants | Journal of Autism and Developmental Disorders | 2014 | 263 |
| 26 | FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States | Genome Medicine | 2012 | 258 |
| 27 | Preliminary Findings of a Telehealth Approach to Parent Training in Autism | Journal of Autism and Developmental Disorders | 2013 | 255 |
| 28 | Atypical object exploration at 12 months of age is associated with autism in a prospective sample | Autism | 2008 | 252 |
| 29 | Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer’s Disease Brain: A Review | Frontiers in Aging Neuroscience | 2018 | 249 |
| 30 | Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome | Nature Reviews Drug Discovery | 2018 | 247 |
| 31 | Autism Symptoms and Internalizing Psychopathology in Girls and Boys with Autism Spectrum Disorders | Journal of Autism and Developmental Disorders | 2012 | 233 |
| 32 | Fragile X-associated tremor/ataxia syndrome — features, mechanisms and management | Nature Reviews Neurology | 2016 | 221 |
| 33 | The operation of pattern separation and pattern completion processes associated with different attributes or domains of memory | Neuroscience and Biobehavioral Reviews | 2013 | 218 |
| 34 | Fragile-X syndrome and fragile X-associated tremor/ataxia syndrome: two faces of FMR1 | Lancet Neurology, The | 2007 | 212 |
| 35 | A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome | Journal of Developmental and Behavioral Pediatrics | 2013 | 212 |
| 36 | Germline Chd8 haploinsufficiency alters brain development in mouse | Nature Neuroscience | 2017 | 210 |
| 37 | Complete genomic and epigenetic maps of human centromeres | Science | 2022 | 204 |
| 38 | Adolescent impatience decreases with increased frontostriatal connectivity | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 203 |
| 39 | Can one hour per week of therapy lead to lasting changes in young children with autism? | Autism | 2009 | 196 |
| 40 | Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation | Molecular Psychiatry | 2017 | 191 |
| 41 | GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism | Neuropsychopharmacology | 2015 | 187 |
| 42 | A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins | Molecular Psychiatry | 2007 | 184 |
| 43 | Modeling fragile X syndrome in the <i>Fmr1</i> knockout mouse | Intractable and Rare Diseases Research | 2014 | 183 |
| 44 | Increased Extra-axial Cerebrospinal Fluid in High-Risk Infants Who Later Develop Autism | Biological Psychiatry | 2017 | 173 |
| 45 | Increased Rate of Amygdala Growth in Children Aged 2 to 4 Years With Autism Spectrum Disorders | Archives of General Psychiatry | 2012 | 170 |
| 46 | Neural representation of interval encoding and decision making | Cognitive Brain Research | 2004 | 168 |
| 47 | Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders | Frontiers in Cellular Neuroscience | 2018 | 168 |
| 48 | Cognitive profile of fragile X premutation carriers with and without fragile X-associated tremor/ataxia syndrome. | Neuropsychology | 2008 | 167 |
| 49 | Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms | Brain, Behavior, and Immunity | 2018 | 163 |
| 50 | Immunological and autoimmune considerations of Autism Spectrum Disorders | Journal of Autoimmunity | 2013 | 159 |
