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Top Articles

#TitleJournalYearCitations
1Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cellsNature Communications2020271
2High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis–Ferroptosis Synergistic Tumor TherapyACS Nano2021266
3IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptorNature Immunology2021170
4A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapyNano Today2020126
5A Nanozyme‐Based Artificial Peroxisome Ameliorates Hyperuricemia and Ischemic StrokeAdvanced Functional Materials2021116
6Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 PatientsFrontiers in Immunology2020101
7Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du decoction in the treatment of COVID-19Phytomedicine2021100
8HPV post-infection microenvironment and cervical cancerCancer Letters202197
9Pro-necrotic molecules impact local immunosurveillance in human breast cancerOncoImmunology201788
10seq-ImmuCC: Cell-Centric View of Tissue Transcriptome Measuring Cellular Compositions of Immune Microenvironment From Mouse RNA-Seq DataFrontiers in Immunology201875
11When Hepatitis B Virus Meets InterferonsFrontiers in Microbiology201871
12Fenozyme Protects the Integrity of the Blood–Brain Barrier against Experimental Cerebral MalariaNano Letters201970
13Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunityNature Cell Biology202070
14The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinomaJournal of Experimental and Clinical Cancer Research201863
15Comparative Transcriptome Analysis Reveals the Intensive Early Stage Responses of Host Cells to SARS-CoV-2 InfectionFrontiers in Microbiology202062
16Clinical and translational values of spatial transcriptomicsSignal Transduction and Targeted Therapy202261
17A natural drug entry channel in the ferritin nanocageNano Today202057
18Antimalarial drug mefloquine inhibits nuclear factor kappa B signaling and induces apoptosis in colorectal cancer cellsCancer Science201855
19The renaissance of anti‐neoplastic immunity from tumor cell demiseImmunological Reviews201753
20Ubiquitin specific peptidase 5 regulates colorectal cancer cell growth by stabilizing Tu translation elongation factorTheranostics201953
21Research progress in peanut allergens and their allergenicity reductionTrends in Food Science and Technology201951
22The Acute-Phase Protein Orosomucoid Regulates Food Intake and Energy Homeostasis via Leptin Receptor Signaling PathwayDiabetes201650
23Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBxFrontiers in Immunology201846
24Structure and function of USP5: Insight into physiological and pathophysiological rolesPharmacological Research202046
25LAMB3 promotes tumour progression through the AKT–FOXO3/4 axis and is transcriptionally regulated by the BRD2/acetylated ELK4 complex in colorectal cancerOncogene202046
26Nicotine protects against DSS colitis through regulating microRNA-124 and STAT3Journal of Molecular Medicine201743
27Colorimetric and fluorometric determination of uric acid based on the use of nitrogen-doped carbon quantum dots and silver triangular nanoprismsMikrochimica Acta201839
28CCBE1 promotes tumor lymphangiogenesis and is negatively regulated by TGFβ signaling in colorectal cancerTheranostics202037
29Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle EnduranceScientific Reports201634
30Colorimetric determination of glutathione in human serum and cell lines by exploiting the peroxidase-like activity of CuS-polydopamine-Au compositeAnalytical and Bioanalytical Chemistry201834
31Food irradiation: a promising technology to produce hypoallergenic food with high qualityCritical Reviews in Food Science and Nutrition202234
32Co-inhibition of BET proteins and NF-κB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressionsCell Death and Disease201833
33Effects of fermentation with Bacillus natto on the allergenicity of peanutLWT - Food Science and Technology202132
34Recent advances in alleviating food allergenicity through fermentationCritical Reviews in Food Science and Nutrition202232
35Rapid identification of human‐infecting virusesTransboundary and Emerging Diseases201931
36Small heat shock protein CRYAB inhibits intestinal mucosal inflammatory responses and protects barrier integrity through suppressing IKKβ activityMucosal Immunology201929
37MicroRNA-381-3p Functions as a Dual Suppressor of Apoptosis and Necroptosis and Promotes Proliferation of Renal Cancer CellsFrontiers in Cell and Developmental Biology202028
38Rewiring Mitochondrial Metabolism for CD8+ T Cell Memory Formation and Effective Cancer ImmunotherapyFrontiers in Immunology202026
39Compositional diversity and evolutionary pattern of coronavirus accessory proteinsBriefings in Bioinformatics202126
40Robo1-specific chimeric antigen receptor natural killer cell therapy for pancreatic ductal adenocarcinoma with liver metastasisJournal of Cancer Research and Therapeutics202026
41Nitidine chloride exerts anti-inflammatory action by targeting Topoisomerase I and enhancing IL-10 productionPharmacological Research201925
42Regulating Innate and Adaptive Immunity for Controlling SIV Infection by 25-HydroxycholesterolFrontiers in Immunology201823
43Nanomaterials incorporated ultrasound contrast agents for cancer theranosticsCancer Biology and Medicine201621
44A bifunctional NiCo2S4/reduced graphene oxide@polyaniline nanocomposite as a highly-efficient electrode for glucose and rutin detectionNew Journal of Chemistry201821
45Regulation of Early Host Immune Responses Shapes the Pathogenicity of Avian Influenza A VirusFrontiers in Microbiology201921
46Overexpression of CMTM7 inhibits cell growth and migration in liver cancerKaohsiung Journal of Medical Sciences201921
47Therapy-induced microenvironmental changes in cancerJournal of Molecular Medicine201619
48Estrogen weakens muscle endurance via estrogen receptor-p38 MAPK-mediated orosomucoid (ORM) suppressionExperimental and Molecular Medicine201819
49A novel index of protein-protein interface propensity improves interface residue recognitionBMC Systems Biology201618
50LincRNA‐EPS alleviates severe acute pancreatitis by suppressing HMGB1‐triggered inflammation in pancreatic macrophagesImmunology202118