| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Explainable Artificial Intelligence (XAI): Concepts, taxonomies, opportunities and challenges toward responsible AI | Information Fusion | 2020 | 3,332 |
| 3 | Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients | Science | 2020 | 2,374 |
| 4 | A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement | Journal of Hepatology | 2020 | 2,171 |
| 5 | Approaches to treat immune hot, altered and cold tumours with combination immunotherapies | Nature Reviews Drug Discovery | 2019 | 2,005 |
| 6 | Autoantibodies against type I IFNs in patients with life-threatening COVID-19 | Science | 2020 | 1,983 |
| 7 | Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 | Science | 2020 | 1,749 |
| 8 | Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease | Nature Genetics | 2014 | 1,685 |
| 9 | Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer | New England Journal of Medicine | 2020 | 1,513 |
| 10 | GW170817: Measurements of Neutron Star Radii and Equation of State | Physical Review Letters | 2018 | 1,473 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 12 | Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism | Cell | 2020 | 1,422 |
| 13 | Ferroptosis: molecular mechanisms and health implications | Cell Research | 2021 | 1,406 |
| 14 | Hematological findings and complications of COVID‐19 | American Journal of Hematology | 2020 | 1,354 |
| 15 | Broadening horizons: the role of ferroptosis in cancer | Nature Reviews Clinical Oncology | 2021 | 1,216 |
| 16 | Emerging Properties in Self-Supervised Vision Transformers | Nature Reviews Clinical Oncology | 2021 | 1,188 |
| 17 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management | Nature Reviews Gastroenterology and Hepatology | 2020 | 1,155 |
| 18 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 19 | GW190425: Observation of a Compact Binary Coalescence with Total Mass ∼ 3.4 M⊙ | Astrophysical Journal Letters | 2020 | 1,049 |
| 20 | TRY plant trait database – enhanced coverage and open access | Global Change Biology | 2020 | 1,038 |
| 21 | CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands | Nature Medicine | 2016 | 1,001 |
| 22 | Fungal microbiota dysbiosis in IBD | Gut | 2017 | 939 |
| 23 | Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study | Lancet, The | 2020 | 931 |
| 24 | Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry | Annals of the Rheumatic Diseases | 2020 | 908 |
| 25 | Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes | Journal of Eukaryotic Microbiology | 2019 | 904 |
| 26 | Gut microbiota-derived metabolites as key actors in inflammatory bowel disease | Nature Reviews Gastroenterology and Hepatology | 2020 | 893 |
| 27 | Estimating the burden of SARS-CoV-2 in France | Science | 2020 | 880 |
| 28 | Tertiary lymphoid structures in the era of cancer immunotherapy | Nature Reviews Cancer | 2019 | 879 |
| 29 | Consolidation alters motor sequence-specific distributed representations | ELife | 2019 | 863 |
| 30 | The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy | Nature Reviews Cancer | 2020 | 860 |
| 31 | IgA dominates the early neutralizing antibody response to SARS-CoV-2 | Science Translational Medicine | 2021 | 840 |
| 32 | 150 M⊙">GW190521: A Binary Black Hole Merger with a Total Mass of 150 M⊙ | Physical Review Letters | 2020 | 836 |
| 33 | 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease | European Heart Journal | 2021 | 830 |
| 34 | The 16th Data Release of the Sloan Digital Sky Surveys: First Release from the APOGEE-2 Southern Survey and Full Release of eBOSS Spectra | Astrophysical Journal, Supplement Series | 2020 | 826 |
| 35 | Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial | Lancet, The | 2019 | 818 |
| 36 | A comprehensive quantification of global nitrous oxide sources and sinks | Nature | 2020 | 814 |
| 37 | Wannier90 as a community code: new features and applications | Journal of Physics Condensed Matter | 2020 | 807 |
| 38 | The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the Extended Baryon Oscillation Spectroscopic Survey and from the Second Phase of the Apache Point Observatory Galactic Evolution Experiment | Astrophysical Journal, Supplement Series | 2018 | 796 |
| 39 | Climate change and interconnected risks to sustainable development in the Mediterranean | Nature Climate Change | 2018 | 776 |
| 40 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 41 | 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5) | Annals of Oncology | 2020 | 761 |
| 42 | Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study | Lancet Oncology, The | 2018 | 742 |
| 43 | A complete catalogue of high-quality topological materials | Nature | 2019 | 721 |
| 44 | ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation | Nature | 2019 | 693 |
| 45 | Neuroinvasion of SARS-CoV-2 in human and mouse brain | Journal of Experimental Medicine | 2021 | 677 |
| 46 | EULAR recommendations for the management of antiphospholipid syndrome in adults | Annals of the Rheumatic Diseases | 2019 | 664 |
| 47 | Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study | Diabetologia | 2020 | 638 |
| 48 | Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164 | Journal of Clinical Oncology | 2020 | 623 |
| 49 | Autophagy in major human diseases | EMBO Journal | 2021 | 615 |
| 50 | EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update | Annals of the Rheumatic Diseases | 2020 | 609 |
