Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 516 |
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis | Cell | 2019 | 359 |
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa | Nature Genetics | 2019 | 303 |
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors | Nature Genetics | 2019 | 181 |
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries | Nature Genetics | 2019 | 156 |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals | Nature Communications | 2019 | 89 |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility | Nature Communications | 2019 | 81 |
O7.7. NEUROBIOLOGICAL ROOTS OF SCHIZOPHRENIA | Schizophrenia Bulletin | 2019 | 78 |
Interrogation of human hematopoiesis at single-cell and single-variant resolution | Nature Genetics | 2019 | 77 |
Machine learning and feature selection for drug response prediction in precision oncology applications | Biophysical Reviews | 2019 | 76 |
DrugComb: an integrative cancer drug combination data portal | Nucleic Acids Research | 2019 | 71 |
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions | Cell Metabolism | 2019 | 69 |
Exome sequencing of Finnish isolates enhances rare-variant association power | Nature | 2019 | 69 |
Metabolic signature of extracellular vesicles depends on the cell culture conditions | Journal of Extracellular Vesicles | 2019 | 60 |
Genetic architecture of human plasma lipidome and its link to cardiovascular disease | Nature Communications | 2019 | 58 |
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer | PLoS Computational Biology | 2019 | 53 |
Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland | American Journal of Human Genetics | 2019 | 50 |
Influence of young adult cognitive ability and additional education on later-life cognition | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 46 |
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion | Nature Genetics | 2019 | 45 |
Breast cancer outcome prediction with tumour tissue images and machine learning | Breast Cancer Research and Treatment | 2019 | 41 |
Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns | Hypertension | 2019 | 40 |
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans | Nature Communications | 2019 | 40 |
Associations of autozygosity with a broad range of human phenotypes | Nature Communications | 2019 | 40 |
Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci | Clinical Epigenetics | 2019 | 40 |
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI | Science Advances | 2019 | 39 |