| # | Title | Journal | Year | Citations |
|---|
| 1 | B cells and tertiary lymphoid structures promote immunotherapy response | Nature | 2020 | 1,421 |
| 2 | Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer | Nature Reviews Cancer | 2015 | 839 |
| 3 | GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice | Journal of Clinical Investigation | 2009 | 605 |
| 4 | Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 564 |
| 5 | Metabolic control of cell death | Science | 2014 | 527 |
| 6 | Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies | Kidney International | 2012 | 454 |
| 7 | Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin | Clinical Cancer Research | 2013 | 301 |
| 8 | Endothelium structure and function in kidney health and disease | Nature Reviews Nephrology | 2019 | 292 |
| 9 | Tertiary lymphoid structures, drivers of the anti‐tumor responses in human cancers | Immunological Reviews | 2016 | 277 |
| 10 | TP53, STK11, and EGFR Mutations Predict Tumor Immune Profile and the Response to Anti–PD-1 in Lung Adenocarcinoma | Clinical Cancer Research | 2018 | 257 |
| 11 | Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma | Clinical Cancer Research | 2017 | 252 |
| 12 | New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk | Nature Communications | 2016 | 245 |
| 13 | Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention | Frontiers in Immunology | 2016 | 238 |
| 14 | Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes | Molecular Endocrinology | 2009 | 236 |
| 15 | Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome | Blood | 2013 | 207 |
| 16 | Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications | Frontiers in Immunology | 2017 | 189 |
| 17 | Complement alternative pathway acts as a positive feedback amplification of neutrophil activation | Blood | 2011 | 188 |
| 18 | Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome | Kidney International | 2010 | 163 |
| 19 | The CD46-Jagged1 interaction is critical for human TH1 immunity | Nature Immunology | 2012 | 163 |
| 20 | Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth | Cancer Immunology Research | 2019 | 153 |
| 21 | Endoplasmic reticulum proteostasis in hepatic steatosis | Nature Reviews Endocrinology | 2016 | 149 |
| 22 | Alternative complement pathway assessment in patients with atypical HUS | Journal of Immunological Methods | 2011 | 140 |
| 23 | The immune contexture of primary and metastatic human tumours | Current Opinion in Immunology | 2014 | 137 |
| 24 | A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function | Blood | 2012 | 128 |
| 25 | Implication of gut microbiota metabolites in cardiovascular and metabolic diseases | Cellular and Molecular Life Sciences | 2018 | 127 |
| 26 | β-Lactamase inhibition by avibactam in Mycobacterium abscessus | Journal of Antimicrobial Chemotherapy | 2015 | 126 |
| 27 | Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9 | Diabetes | 2011 | 119 |
| 28 | The Immune Microenvironment of Human Tumors: General Significance and Clinical Impact | Cancer Microenvironment | 2013 | 119 |
| 29 | Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome | Blood | 2015 | 112 |
| 30 | Determination of collagen fibril size via absolute measurements of second-harmonic generation signals | Nature Communications | 2014 | 107 |
| 31 | Enamel Defects Reflect Perinatal Exposure to Bisphenol A | American Journal of Pathology | 2013 | 106 |
| 32 | Characteristics of tertiary lymphoid structures in primary cancers | OncoImmunology | 2013 | 103 |
| 33 | Aldosterone, mineralocorticoid receptor, and heart failure | Molecular and Cellular Endocrinology | 2012 | 100 |
| 34 | The prognostic impact of anti-cancer immune response: a novel classification of cancer patients | Seminars in Immunopathology | 2011 | 97 |
| 35 | Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H–Related Protein 5 Deficiency | American Journal of Kidney Diseases | 2012 | 95 |
| 36 | C5 nephritic factors drive the biological phenotype of C3 glomerulopathies | Kidney International | 2017 | 93 |
| 37 | Transcriptomic analysis of the tumor microenvironment to guide prognosis and immunotherapies | Cancer Immunology, Immunotherapy | 2018 | 89 |
| 38 | The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort | Journal of Translational Medicine | 2019 | 88 |
| 39 | Sodium Excretion in Response to Vasopressin and Selective Vasopressin Receptor Antagonists | Journal of the American Society of Nephrology: JASN | 2008 | 87 |
| 40 | Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia | Journal of Experimental Medicine | 2015 | 85 |
| 41 | Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal Recessive FAM20A Mutations | Nephron Physiology | 2013 | 84 |
| 42 | CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration | Journal of Neuroinflammation | 2010 | 81 |
| 43 | Publication Trends in Bariatric Surgery: a Bibliometric Study | Obesity Surgery | 2016 | 81 |
| 44 | PD-L1 Expression and CD8+ T-cell Infiltrate are Associated with Clinical Progression in Patients with Node-positive Prostate Cancer | European Urology Focus | 2019 | 81 |
| 45 | Dentin-Pulp Complex Regeneration | Advances in Dental Research | 2011 | 75 |
| 46 | Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome | Genetics in Medicine | 2018 | 75 |
| 47 | Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab | Nephrology Dialysis Transplantation | 2016 | 72 |
| 48 | Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats | Diabetologia | 2015 | 70 |
| 49 | Detection of extracellular glucose by GLUT2 contributes to hypothalamic control of food intake | American Journal of Physiology - Endocrinology and Metabolism | 2010 | 69 |
| 50 | Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials | American Journal of Physiology - Endocrinology and Metabolism | 2016 | 67 |
