| # | Title | Journal | Year | Citations |
|---|
| 1 | Complement Factor H Polymorphism in Age-Related Macular Degeneration | Science | 2005 | 4,018 |
| 2 | Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial | Lancet, The | 2012 | 1,294 |
| 3 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
| 4 | Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study group | Cancer | 1981 | 1,025 |
| 5 | gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma | New England Journal of Medicine | 2011 | 809 |
| 6 | Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices | Npj Digital Medicine | 2018 | 796 |
| 7 | Peripheral-Blood Stem Cells versus Bone Marrow from Unrelated Donors | New England Journal of Medicine | 2012 | 762 |
| 8 | A Simplified Severity Scale for Age-Related Macular Degeneration | JAMA Ophthalmology | 2005 | 697 |
| 9 | Improvement in Outcomes of Clinical Islet Transplantation: 1999–2010 | Diabetes Care | 2012 | 665 |
| 10 | Contemporary Patterns of Spontaneous Labor With Normal Neonatal Outcomes | Obstetrics and Gynecology | 2010 | 630 |
| 11 | Risk Factors for the Incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS)AREDS report no. 19 | Ophthalmology | 2005 | 609 |
| 12 | Accelerated Titration Designs for Phase I Clinical Trials in Oncology | Journal of the National Cancer Institute | 1997 | 576 |
| 13 | Alternative donor transplantation after reduced intensity conditioning: results of parallel phase 2 trials using partially HLA-mismatched related bone marrow or unrelated double umbilical cord blood grafts | Blood | 2011 | 549 |
| 14 | Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 548 |
| 15 | A Randomized Trial Comparing the Efficacy and Safety of Intravitreal Triamcinolone With Observation to Treat Vision Loss Associated With Macular Edema Secondary to Central Retinal Vein Occlusion | JAMA Ophthalmology | 2009 | 537 |
| 16 | Immunotherapy with a Ragweed–Toll-Like Receptor 9 Agonist Vaccine for Allergic Rhinitis | New England Journal of Medicine | 2006 | 521 |
| 17 | Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation | Blood | 2013 | 507 |
| 18 | Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention (X:BOT): a multicentre, open-label, randomised controlled trial | Lancet, The | 2018 | 502 |
| 19 | Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes | Journal of Clinical Oncology | 2017 | 495 |
| 20 | Outcomes of Kidney Transplantation in HIV-Infected Recipients | New England Journal of Medicine | 2010 | 493 |
| 21 | A Randomized Trial Comparing the Efficacy and Safety of Intravitreal Triamcinolone With Standard Care to Treat Vision Loss Associated With Macular Edema Secondary to Branch Retinal Vein Occlusion | JAMA Ophthalmology | 2009 | 476 |
| 22 | Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy | JAMA - Journal of the American Medical Association | 2014 | 471 |
| 23 | Analysis of Gene Expression Data Using BRB-Array Tools | Cancer Informatics | 2007 | 470 |
| 24 | Contemporary cesarean delivery practice in the United States | American Journal of Obstetrics and Gynecology | 2010 | 468 |
| 25 | Intracoronary Cardiosphere-Derived Cells After Myocardial Infarction | Journal of the American College of Cardiology | 2014 | 468 |
| 26 | Adjunctive Counseling During Brief and Extended Buprenorphine-Naloxone Treatment for Prescription Opioid Dependence | Archives of General Psychiatry | 2011 | 463 |
| 27 | Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys | Nature | 2012 | 452 |
| 28 | Respiratory Morbidity in Late Preterm Births | JAMA - Journal of the American Medical Association | 2010 | 446 |
| 29 | Efficacy Results of a Trial of a Herpes Simplex Vaccine | New England Journal of Medicine | 2012 | 439 |
| 30 | A Prospective, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial Comparing Early (7 Day) Corticosteroid Cessation Versus Long-Term, Low-Dose Corticosteroid Therapy | Annals of Surgery | 2008 | 420 |
| 31 | Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation | Blood | 2010 | 419 |
| 32 | Blood and Marrow Transplant Clinical Trials Network Toxicity Committee Consensus Summary: Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation | Biology of Blood and Marrow Transplantation | 2005 | 406 |
| 33 | Safety and Immunogenicity of Tetanus Diphtheria and Acellular Pertussis (Tdap) Immunization During Pregnancy in Mothers and Infants | JAMA - Journal of the American Medical Association | 2014 | 397 |
| 34 | Association Between C-Reactive Protein and Age-Related Macular Degeneration | JAMA - Journal of the American Medical Association | 2004 | 394 |
| 35 | The Relationship of Dietary Carotenoid and Vitamin A, E, and C Intake With Age-Related Macular Degeneration in a Case-Control Study | JAMA Ophthalmology | 2007 | 393 |
| 36 | Measuring Response in Solid Tumors: Unidimensional Versus Bidimensional Measurement | Journal of the National Cancer Institute | 1999 | 375 |
| 37 | Potential Public Health Impact of Age-Related Eye Disease Study Results | JAMA Ophthalmology | 2003 | 355 |
| 38 | The effect of deprenyl and levodopa on the progression of Parkinson's disease | Annals of Neurology | 1995 | 341 |
| 39 | The natural history of milk allergy in an observational cohort | Journal of Allergy and Clinical Immunology | 2013 | 329 |
| 40 | The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters | FASEB Journal | 2013 | 328 |
| 41 | A Randomized Study of Three Interventions for Aspiration of Thin Liquids in Patients With Dementia or Parkinson’s Disease | Journal of Speech, Language, and Hearing Research | 2008 | 321 |
| 42 | Representation of older patients in cancer treatment trials | Cancer | 1994 | 317 |
| 43 | Anxiety, Sensory Over-Responsivity, and Gastrointestinal Problems in Children with Autism Spectrum Disorders | Journal of Abnormal Child Psychology | 2013 | 315 |
| 44 | Early-life gut microbiome composition and milk allergy resolution | Journal of Allergy and Clinical Immunology | 2016 | 307 |
| 45 | Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol | Genome Biology | 2001 | 304 |
| 46 | Tacrolimus with Mycophenolate Mofetil (MMF) or Sirolimus vs. Cyclosporine with MMF in Cardiac Transplant Patients: 1-Year Report | American Journal of Transplantation | 2006 | 298 |
| 47 | Randomized Comparison of Allogeneic Versus Autologous Mesenchymal Stem Cells for Nonischemic Dilated Cardiomyopathy | Journal of the American College of Cardiology | 2017 | 297 |
| 48 | Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans | Vaccine | 2001 | 296 |
| 49 | A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus11This study was sponsored by a grant from Fujisawa USA, Deerfield, Illinois.22The authors were working on behalf of the Tacrolimus US Heart Transplant Multicenter Study Group. Other members of the Study Group included (principal investigator listed first): UTAH Cardiac Transplant Program, Salt Lake City, Utah: David O. Taylor, MD | Journal of Heart and Lung Transplantation | 1999 | 294 |
| 50 | Potent Induction Immunotherapy Promotes Long-Term Insulin Independence After Islet Transplantation in Type 1 Diabetes | American Journal of Transplantation | 2012 | 293 |
