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Most Cited Articles of Wellcome Trust Centre for Cell-Matrix Research in 2010

Regulation of breast cancer stem cell activity by signaling through the Notch4 receptorCancer Research2010410
Superoxide dismutase downregulation in osteoarthritis progression and end-stage diseaseAnnals of the Rheumatic Diseases2010158
Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronanJournal of Biological Chemistry2010153
Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retinaJournal of Biological Chemistry2010136
Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF betaJournal of Cell Science2010131
Cell-matrix interactions in mammary gland development and breast cancerCold Spring Harbor Perspectives in Biology2010108
The unfolded protein response and its relevance to connective tissue diseasesCell and Tissue Research2010106
Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophyAnnals of the Rheumatic Diseases201097
Focal adhesions are sites of integrin extensionJournal of Cell Biology201091
The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2Journal of Biological Chemistry201083
The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassemblyEMBO Reports201081
Pseudomonas syringae virulence factor syringolin A counteracts stomatal immunity by proteasome inhibitionMolecular Plant-Microbe Interactions201080
The potential of stem cells in the treatment of knee cartilage defectsKnee201075
The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tensionBiomaterials201071
Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migrationJournal of Cell Biology201068
Breast cancer stem cells: something out of notching?Cancer Research201067
Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathologyBiochemical Society Transactions201067
Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cellsBiochemical Journal201066
Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3Matrix Biology201060
Molecular basis of coiled-coil oligomerization-state specificityProceedings of the National Academy of Sciences of the United States of America201055
A new method for describing the helical conformation of collagen: dependence of the triple helical twist on amino acid sequenceJournal of Structural Biology201055
Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditionsJournal of Orthopaedic Research201054
An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasiaCell Stress and Chaperones201051
An experimental model for studying the biomechanics of embryonic tendon: Evidence that the development of mechanical properties depends on the actinomyosin machineryMatrix Biology201046
Drosophila growth cones: a genetically tractable platform for the analysis of axonal growth dynamicsDevelopmental Neurobiology201044