| # | Title | Journal | Year | Citations |
|---|
| 1 | The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus | Nature | 1984 | 3,646 |
| 2 | Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial | Lancet, The | 2004 | 3,502 |
| 3 | Updated Clinical Classification of Pulmonary Hypertension | Journal of the American College of Cardiology | 2013 | 2,865 |
| 4 | Psychophysiological and Modulatory Interactions in Neuroimaging | NeuroImage | 1997 | 2,807 |
| 5 | Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease | New England Journal of Medicine | 2010 | 2,359 |
| 6 | The development of a six‐item short‐form of the state scale of the Spielberger State—Trait Anxiety Inventory (STAI) | British Journal of Clinical Psychology | 1992 | 2,335 |
| 7 | Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori | Lancet, The | 1993 | 2,065 |
| 8 | The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. | Journal of Clinical Investigation | 1998 | 1,945 |
| 9 | Mitochondrial Complex I Deficiency in Parkinson's Disease | Journal of Neurochemistry | 1990 | 1,860 |
| 10 | Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study | BMJ: British Medical Journal | 2000 | 1,737 |
| 11 | C-reactive protein: a critical update | Journal of Clinical Investigation | 2003 | 1,673 |
| 12 | Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1 | Journal of Clinical Endocrinology and Metabolism | 1997 | 1,645 |
| 13 | Differential Effects of Early Hippocampal Pathology on Episodic and Semantic Memory | Science | 1997 | 1,600 |
| 14 | Sequence and structure of a human glucose transporter | Science | 1985 | 1,522 |
| 15 | Effects of Attention and Emotion on Face Processing in the Human Brain | Neuron | 2001 | 1,508 |
| 16 | Prognosis of HIV-1-infected patients starting highly active antiretroviral therapy: a collaborative analysis of prospective studies | Lancet, The | 2002 | 1,415 |
| 17 | Physiology and Pathophysiology of Purinergic Neurotransmission | Physiological Reviews | 2007 | 1,396 |
| 18 | Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses | BMJ: British Medical Journal | 2000 | 1,384 |
| 19 | Effectiveness and efficiency of search methods in systematic reviews of complex evidence: audit of primary sources | BMJ: British Medical Journal | 2005 | 1,340 |
| 20 | MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE | Lancet, The | 1989 | 1,248 |
| 21 | STROCSS 2019 Guideline: Strengthening the reporting of cohort studies in surgery | International Journal of Surgery | 2019 | 1,248 |
| 22 | The mitochondrial genome: structure, transcription, translation and replication | Biochimica Et Biophysica Acta - Bioenergetics | 1999 | 1,220 |
| 23 | Free Radicals in Biology: Oxidative Stress and the Effects of Ionizing Radiation | International Journal of Radiation Biology | 1994 | 1,219 |
| 24 | THE PREHENSILE MOVEMENTS OF THE HUMAN HAND | Journal of Bone and Joint Surgery: British Volume | 1956 | 1,202 |
| 25 | Changing patterns of mortality across Europe in patients infected with HIV-1 | Lancet, The | 1998 | 1,182 |
| 26 | Decline in the AIDS and death rates in the EuroSIDA study: an observational study | Lancet, The | 2003 | 1,157 |
| 27 | A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1 | Science | 2007 | 1,136 |
| 28 | Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies | European Heart Journal | 2006 | 1,129 |
| 29 | Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide | FEBS Letters | 1994 | 1,109 |
| 30 | Definitions of Cytomegalovirus Infection and Disease in Transplant Recipients | Clinical Infectious Diseases | 2002 | 1,093 |
| 31 | Vaccine-induced escape mutant of hepatitis B virus | Lancet, The | 1990 | 1,071 |
| 32 | A simple clinical colitis activity index | Gut | 1998 | 1,054 |
| 33 | Evidence based cardiology: Psychosocial factors in the aetiology and prognosis of coronary heart disease: systematic review of prospective cohort studies | BMJ: British Medical Journal | 1999 | 1,052 |
| 34 | A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane | Cell | 1990 | 1,046 |
| 35 | Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study | Lancet Oncology, The | 2015 | 1,031 |
| 36 | Virtual outreach: a randomised controlled trial and economic evaluation of joint teleconferenced medical consultations | Health Technology Assessment | 2004 | 1,016 |
| 37 | Dose intensification with autologous bone-marrow transplantation in relapsed and resistant Hodgkin's disease: results of a BNLI randomised trial | Lancet, The | 1993 | 993 |
| 38 | The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis.. | British Journal of Dermatology | 1994 | 990 |
| 39 | Neural Responses during Anticipation of a Primary Taste Reward | Neuron | 2002 | 990 |
| 40 | International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function | Pharmacological Reviews | 1998 | 980 |
| 41 | A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis | Nature Genetics | 1998 | 968 |
| 42 | A proposed system for the nomenclature of hepatitis C viral genotypes | Hepatology | 1994 | 962 |
| 43 | Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice | Nature | 2000 | 956 |
| 44 | Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. | Circulation | 1993 | 912 |
| 45 | Andrology: Polycystic ovary syndrome: the spectrum of the disorder in 1741 patients | Human Reproduction | 1995 | 912 |
| 46 | Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis | BMJ: British Medical Journal | 2000 | 905 |
| 47 | Structure of human factor VIII | Nature | 1984 | 869 |
| 48 | COPD exacerbations: defining their cause and prevention | Lancet, The | 2007 | 863 |
| 49 | Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma | Lancet, The | 1995 | 860 |
| 50 | Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study | Clinical Endocrinology | 2000 | 843 |
