| # | Title | Journal | Year | Citations |
|---|
| 1 | Haemodynamic definitions and updated clinical classification of pulmonary hypertension | European Respiratory Journal | 2019 | 2,583 |
| 2 | Beneficial effects of weight loss associated with moderate calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: a pilot study | Annals of the Rheumatic Diseases | 2000 | 274 |
| 3 | 2018 Joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous cardiovascular interventions: a joint consensus document of the European Heart Rhythm Association (EHRA), European Society of Cardiology Working Group on Thrombosis, European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm So | Europace | 2019 | 209 |
| 4 | Antimicrobial resistance in the next 30 years, humankind, bugs and drugs: a visionary approach | Intensive Care Medicine | 2017 | 199 |
| 5 | SeQuent Please World Wide Registry | Journal of the American College of Cardiology | 2012 | 186 |
| 6 | Resistance to Colistin Associated with a Single Amino Acid Change in Protein PmrB among Klebsiella pneumoniae Isolates of Worldwide Origin | Antimicrobial Agents and Chemotherapy | 2014 | 183 |
| 7 | Antimicrobial stewardship across 47 South African hospitals: an implementation study | Lancet Infectious Diseases, The | 2016 | 165 |
| 8 | Heteroresistance to Colistin in Klebsiella pneumoniae Associated with Alterations in the PhoPQ Regulatory System | Antimicrobial Agents and Chemotherapy | 2015 | 155 |
| 9 | A global call from five countries to collaborate in antibiotic stewardship: united we succeed, divided we might fail | Lancet Infectious Diseases, The | 2017 | 150 |
| 10 | Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54 | European Heart Journal | 2016 | 138 |
| 11 | Genetic Features of MCR-1-Producing Colistin-Resistant Escherichia coli Isolates in South Africa | Antimicrobial Agents and Chemotherapy | 2016 | 135 |
| 12 | Global Unmet Needs in Cardiac Surgery | | 2018 | 131 |
| 13 | Elderly Patients With Acute Coronary Syndromes Managed Without Revascularization | Circulation | 2013 | 130 |
| 14 | Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) | World Journal of Emergency Surgery | 2016 | 130 |
| 15 | In Vivo Development of Ertapenem Resistance in a Patient with Pneumonia Caused by Klebsiella pneumoniae with an Extended-Spectrum -Lactamase | Clinical Infectious Diseases | 2006 | 126 |
| 16 | Effect of Alirocumab on Mortality After Acute Coronary Syndromes | Circulation | 2019 | 107 |
| 17 | Duration of Dual Antiplatelet Therapy After Coronary Stenting | Journal of the American College of Cardiology | 2015 | 105 |
| 18 | Prevention of Stroke with the Addition of Ezetimibe to Statin Therapy in Patients With Acute Coronary Syndrome in IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial) | Circulation | 2017 | 102 |
| 19 | Esomeprazole 20 mg and lansoprazole 15 mg in maintaining healed reflux oesophagitis: Metropole study results | Alimentary Pharmacology and Therapeutics | 2003 | 99 |
| 20 | Emergence of OXA-48 and OXA-181 Carbapenemases among Enterobacteriaceae in South Africa and Evidence of In Vivo Selection of Colistin Resistance as a Consequence of Selective Decontamination of the Gastrointestinal Tract | Journal of Clinical Microbiology | 2013 | 94 |
| 21 | Emergence of New Delhi Metallo-Beta-Lactamase (NDM-1) and Klebsiella pneumoniae Carbapenemase (KPC-2) in South Africa | Journal of Clinical Microbiology | 2012 | 90 |
| 22 | Long-term Tolerability of Ticagrelor for the Secondary Prevention of Major Adverse Cardiovascular Events | JAMA Cardiology | 2016 | 88 |
| 23 | Pharmacokinetics of once-daily dosing of ertapenem in critically ill patients with severe sepsis | International Journal of Antimicrobial Agents | 2009 | 72 |
| 24 | Efficacy and Safety of Vorapaxar as Approved for Clinical Use in the United States | Journal of the American Heart Association | 2015 | 62 |
| 25 | Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients | South African Medical Journal | 2016 | 59 |
| 26 | From guidelines to practice: a pharmacist-driven prospective audit and feedback improvement model for peri-operative antibiotic prophylaxis in 34 South African hospitals | Journal of Antimicrobial Chemotherapy | 2016 | 58 |
| 27 | Hyposecretion of adrenal androgens and the relation of serum adrenal steroids, serotonin and insulin-like growth factor-1 to clinical features in women with fibromyalgia | Pain | 1999 | 57 |
| 28 | Popliteal artery entrapment syndrome | Seminars in Vascular Surgery | 2003 | 57 |
| 29 | Hemoglobin glutamer‐250 (bovine) in South Africa: consensus usage guidelines from clinician experts who have treated patients | Transfusion | 2016 | 55 |
| 30 | Management of acute coronary syndrome in South Africa : insights from the ACCESS (Acute Coronary Events - a Multinational Survey of Current Management Strategies) registry : cardiovascular topics | Cardiovascular Journal of Africa | 2012 | 54 |
| 31 | Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF‐TIMI 48 Trial | Journal of the American Heart Association | 2016 | 53 |
| 32 | High-Level Resistance to Colistin Mediated by Various Mutations in the crrB Gene among Carbapenemase-Producing Klebsiella pneumoniae | Antimicrobial Agents and Chemotherapy | 2017 | 53 |
| 33 | Ischemia Detected on Continuous Electrocardiography After Acute Coronary Syndrome | Journal of the American College of Cardiology | 2009 | 50 |
| 34 | The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship—results from an international cross-sectional survey | World Journal of Emergency Surgery | 2017 | 47 |
| 35 | Longitudinal Changes in Pituitary-Adrenal Hormones in South African Women With Burnout | Endocrine | 2003 | 46 |
| 36 | The Use of Low Dosage X-Ray (Lodox/Statscan) in Major Trauma: Comparison Between Low Dose X-Ray and Conventional X-Ray Techniques | Journal of Trauma | 2006 | 46 |
| 37 | Development and impact of a massive open online course (MOOC) for antimicrobial stewardship | Journal of Antimicrobial Chemotherapy | 2018 | 43 |
| 38 | The spread of carbapenem-resistant Enterobacteriaceae in South Africa: Risk factors for acquisition and prevention | South African Medical Journal | 2012 | 40 |
| 39 | Triple therapy with clarithromycin, omeprazole, and amoxicillin for eradication ofHelicobacter pyloriin duodenal ulcer patients in Asia and Africa | Alimentary Pharmacology and Therapeutics | 2000 | 38 |
| 40 | Coronary Artery Fistula | Journal of the American College of Cardiology | 2009 | 37 |
| 41 | Efficacy and Safety of Enoxaparin Versus Unfractionated Heparin in Patients With ST-Segment Elevation Myocardial Infarction Also Treated With Clopidogrel | Journal of the American College of Cardiology | 2007 | 36 |
| 42 | South Africa: clinical experience with Hemopure | ISBT Science Series | 2006 | 34 |
| 43 | Antimicrobial Susceptibility of Gram-Negative Pathogens Isolated from Patients with Complicated Intra-Abdominal Infections in South African Hospitals (SMART Study 2004–2009): Impact of the New Carbapenem Breakpoints | Surgical Infections | 2012 | 31 |
| 44 | A Safety and Efficacy Evaluation of Hemoglobin-Based Oxygen Carrier HBOC-201 in a Randomized, Multicenter Red Blood Cell Controlled Trial in Noncardiac Surgery Patients | Anesthesia and Analgesia | 2014 | 31 |
| 45 | South African Dyslipidaemia Guideline Consensus Statement: | Journal of Endocrinology Metabolism and Diabetes of South Africa | 2012 | 30 |
| 46 | Does resistance in severe infections caused by methicillin-resistant Staphylococcus aureus give you the ‘creeps’? | Current Opinion in Critical Care | 2012 | 29 |
| 47 | Efficacy and safety of sildenafil citrate (Viagra®) for the treatment of erectile dysfunction in men in Egypt and South Africa | International Journal of Impotence Research | 2003 | 27 |
| 48 | Retinol Binding Protein 4 Concentrations Relate to Enhanced Atherosclerosis in Obese Patients with Rheumatoid Arthritis | PLoS ONE | 2014 | 27 |
| 49 | Marked Independent Relationship between Circulating Interleukin-6 Concentrations and Endothelial Activation in Rheumatoid Arthritis | Mediators of Inflammation | 2013 | 23 |
| 50 | Gunshot Wounds to the Head in Civilian Practice | American Surgeon | 2009 | 22 |
