| # | Title | Journal | Year | Citations |
|---|
| 1 | The Genotype-Tissue Expression (GTEx) project | Nature Genetics | 2013 | 6,815 |
| 2 | Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee | Arthritis and Rheumatism | 1986 | 5,701 |
| 3 | Ranibizumab for Neovascular Age-Related Macular Degeneration | New England Journal of Medicine | 2006 | 5,190 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 5 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD | Neuron | 2011 | 3,833 |
| 6 | Matrix metalloproteinases and their inhibitors in connective tissue remodeling | FASEB Journal | 1991 | 3,086 |
| 7 | Features and uses of high-fidelity medical simulations that lead to effective learning: a BEME systematic review | Medical Teacher | 2005 | 2,861 |
| 8 | Pathophysiology of acute wound healing | Clinics in Dermatology | 2007 | 2,830 |
| 9 | Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer | Journal of Clinical Oncology | 2002 | 2,612 |
| 10 | Monoclonal Antibody to 5-Bromo- and 5-Iododeoxyuridine: A New Reagent for Detection of DNA Replication | Science | 1982 | 2,542 |
| 11 | STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling | Nature | 2008 | 2,526 |
| 12 | Human skin wounds: A major and snowballing threat to public health and the economy | Wound Repair and Regeneration | 2009 | 2,277 |
| 13 | International Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases | Clinical Infectious Diseases | 2011 | 2,194 |
| 14 | Platelet-rich plasma | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics | 1998 | 2,155 |
| 15 | Wound repair and regeneration: Mechanisms, signaling, and translation | Science Translational Medicine | 2014 | 2,114 |
| 16 | STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity | Nature | 2009 | 2,084 |
| 17 | Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America | Clinical Infectious Diseases | 2016 | 2,060 |
| 18 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 19 | Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer | Journal of Clinical Oncology | 2002 | 1,914 |
| 20 | The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip | Arthritis and Rheumatism | 1991 | 1,879 |
| 21 | Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection | American Journal of Gastroenterology | 2002 | 1,878 |
| 22 | Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study | Intensive Care Medicine | 2015 | 1,838 |
| 23 | Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury | Journal of Cerebral Blood Flow and Metabolism | 1987 | 1,818 |
| 24 | Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials | Lancet, The | 2011 | 1,711 |
| 25 | Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease | Nature Genetics | 2014 | 1,685 |
| 26 | FGF23 induces left ventricular hypertrophy | Journal of Clinical Investigation | 2011 | 1,684 |
| 27 | Tissue inhibitors of metalloproteinases: evolution, structure and function | BBA - Proteins and Proteomics | 2000 | 1,570 |
| 28 | The Impact of E-Learning in Medical Education | Academic Medicine | 2006 | 1,548 |
| 29 | Dynamics of Hippocampal Neurogenesis in Adult Humans | Cell | 2013 | 1,523 |
| 30 | Factors predicting the use of technology: Findings from the center for research and education on aging and technology enhancement (create). | Psychology and Aging | 2006 | 1,462 |
| 31 | Perioperative Management of Antithrombotic Therapy | Chest | 2012 | 1,461 |
| 32 | Diabetic Neuropathy: A Position Statement by the American Diabetes Association | Diabetes Care | 2017 | 1,452 |
| 33 | Common genetic determinants of vitamin D insufficiency: a genome-wide association study | Lancet, The | 2010 | 1,385 |
| 34 | Bisphosphonate-Induced Exposed Bone (Osteonecrosis/Osteopetrosis) of the Jaws: Risk Factors, Recognition, Prevention, and Treatment | Journal of Oral and Maxillofacial Surgery | 2005 | 1,378 |
| 35 | Practice Guidelines for the Diagnosis and Management of Skin and Soft-Tissue Infections | Clinical Infectious Diseases | 2005 | 1,338 |
| 36 | Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases | Lancet Infectious Diseases, The | 2013 | 1,328 |
| 37 | Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS | Nature | 2013 | 1,249 |
| 38 | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Trends in Pharmacological Sciences | 2006 | 1,237 |
| 39 | Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions | Nature Neuroscience | 2013 | 1,216 |
| 40 | Depression and Risk for Alzheimer Disease | Archives of General Psychiatry | 2006 | 1,213 |
| 41 | Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis | Nature Genetics | 2013 | 1,213 |
| 42 | Management of Sickle Cell Disease | JAMA - Journal of the American Medical Association | 2014 | 1,189 |
| 43 | A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Nature Genetics | 2016 | 1,167 |
| 44 | Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. | Stroke | 1989 | 1,136 |
| 45 | Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 1,131 |
| 46 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 47 | Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1 | Cell | 1998 | 1,114 |
| 48 | Mesenchymal stem cell perspective: cell biology to clinical progress | Npj Regenerative Medicine | 2019 | 1,113 |
| 49 | Postpartum depression effects on early interactions, parenting, and safety practices: A review | | 2010 | 1,111 |
| 50 | Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein | Nature | 1987 | 1,091 |
