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Top Articles

#TitleJournalYearCitations
1Mitochondria and ApoptosisLWT - Food Science and Technology19987,980
2Understanding the tumor immune microenvironment (TIME) for effective therapyNature Medicine20183,421
3Development of Monocytes, Macrophages, and Dendritic CellsScience20102,471
4Follicular Helper CD4 T Cells (TFH)Annual Review of Immunology20112,391
5Fas Ligand-Induced Apoptosis as a Mechanism of Immune PrivilegeScience19951,936
6Reciprocal TH17 and Regulatory T Cell Differentiation Mediated by Retinoic AcidScience20071,778
7T Follicular Helper Cell Differentiation, Function, and Roles in DiseaseImmunity20141,477
8Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosomeNature Cell Biology20001,358
9Protease activation during apoptosis: Death by a thousand cuts?Cell19951,345
10Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial MembraneCell20021,337
11The Immune Epitope Database (IEDB): 2018 updateNucleic Acids Research20191,329
12Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomasNature19951,305
13Immune and Inflammatory Mechanisms of AtherosclerosisAnnual Review of Immunology20091,249
14MitochondriaCell20031,169
15NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity DataJournal of Immunology20171,153
16Apoptotic PathwaysCell19981,141
17Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growthNature20121,088
18ElliPro: a new structure-based tool for the prediction of antibody epitopesBMC Bioinformatics20081,076
19BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and IndirectlyMolecular Cell20051,065
20BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopesNucleic Acids Research20171,048
21Mutant MHC class II epitopes drive therapeutic immune responses to cancerNature20151,030
22The immune epitope database (IEDB) 3.0Nucleic Acids Research20151,014
23A matter of life and deathCancer Cell20021,008
24Apoptotic PathwaysCell2000968
25The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein LigaseScience1999963
26Apoptotic cell death induced by c-myc is inhibited by bcl-2Nature1992957
27TOWARD AN UNDERSTANDING OF NKT CELL BIOLOGY: Progress and ParadoxesAnnual Review of Immunology2005917
28Breaking the mitochondrial barrierNature Reviews Molecular Cell Biology2001883
29A Unified Model for Apical Caspase ActivationMolecular Cell2003855
30Identifying specificity groups in the T cell receptor repertoireNature2017825
31Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d TetramersJournal of Experimental Medicine2000818
32Type 1 Diabetes: Etiology, Immunology, and Therapeutic StrategiesPhysiological Reviews2011812
33ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6Immunity2011792
34Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced ApoptosisCell1996780
35The role of TNF superfamily members in T-cell function and diseasesNature Reviews Immunology2009767
36A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus ApproachPLoS Computational Biology2008739
37Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitisNature Immunology2009731
38NetMHCpan, a method for MHC class I binding prediction beyond humansImmunogenetics2009725
39Apoptotic Pathways: Ten Minutes to DeadCell2005710
40The unconventional lifestyle of NKT cellsNature Reviews Immunology2002692
41Properties of MHC Class I Presented Peptides That Enhance ImmunogenicityPLoS Computational Biology2013636
42Modified mRNA Vaccines Protect against Zika Virus InfectionCell2017633
43Improved methods for predicting peptide binding affinity to MHC class II moleculesImmunology2018629
44Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their DisposalCell2013621
45T cells from patients with Parkinson’s disease recognize α-synuclein peptidesNature2017618
46Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 ActivationMolecular Cell2007610
47Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II MoleculeJournal of Immunology2003609
48Purinergic regulation of the immune systemNature Reviews Immunology2016607
49NetMHCpan, a Method for Quantitative Predictions of Peptide Binding to Any HLA-A and -B Locus Protein of Known SequencePLoS ONE2007598
50Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope PredictionImmunity2017596