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Broad Institute
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Top Articles
Broad Institute
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11.3K
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1.4M
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4,259
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journals
Most Cited Articles of Broad Institute in 2019
Title
Journal
Year
Citations
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics
2019
917
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nature Genetics
2019
662
Genomic correlates of clinical outcome in advanced prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
2019
383
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
Cell
2019
359
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
American Journal of Human Genetics
2019
348
Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study
JAMA Psychiatry
2019
165
Longitudinal molecular trajectories of diffuse glioma in adults
Nature
2019
151
Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
Nature Communications
2019
147
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Nature
2019
129
Best practices for benchmarking germline small-variant calls in human genomes
Nature Biotechnology
2019
125
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
2019
110
Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
Circulation
2019
104
Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
Cell Metabolism
2019
102
Biological and clinical insights from genetics of insomnia symptoms
Nature Genetics
2019
101
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains
Nature Neuroscience
2019
99
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
Nature Communications
2019
98
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations
PLoS Genetics
2019
90
Transmission of human-associated microbiota along family and social networks
Nature Microbiology
2019
85
Genetics of Common, Complex Coronary Artery Disease
Cell
2019
84
Genetic architecture of subcortical brain structures in 38,851 individuals
Nature Genetics
2019
81
DIPG-02. TRANSLATIONAL MR IMAGING CORRELATES FOR MOLECULAR ANALYSES IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
Neuro-Oncology
2019
78
MEDU-37. NEURONAL DIFFERENTIATION AND CELL-CYCLE PROGRAMS MEDIATE RESPONSE AND RESISTANCE TO BET-BROMODOMAIN INHIBITION IN MYC-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology
2019
78
LGG-04. CLINICO-HISTO-MOLECULAR LANDSCAPE OF EIGHTY-TWO PEDIATRIC AND YOUNG ADULT DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMORS
Neuro-Oncology
2019
78
Identifying Metabolomic Profiles of Insulinemic Dietary Patterns (OR31-03-19)
Current Developments in Nutrition
2019
78
DRES-08. CLINICAL SIGNIFICANCE OF HYPERMUTATION IN GLIOMAS
Neuro-Oncology
2019
78
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