Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish | Journal of Neuroscience | 2006 | 362 |
Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma | Journal of Experimental Medicine | 2006 | 293 |
Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430 | Current Biology | 2006 | 259 |
Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins | Cancer Research | 2006 | 227 |
The influence of recombination on human genetic diversity | PLoS Genetics | 2006 | 185 |
Beringian origins and cryptic speciation events in the fly agaric (Amanita muscaria) | Molecular Ecology | 2006 | 124 |
Optimal two-stage genotyping designs for genome-wide association scans | Genetic Epidemiology | 2006 | 107 |
Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer | Cancer | 2006 | 89 |
Cohypermethylation of p16 and FHIT promoters as a prognostic factor of recurrence in surgically resected stage I non-small cell lung cancer | Cancer Research | 2006 | 76 |
Learning theory: stability is sufficient for generalization and necessary and sufficient for consistency of empirical risk minimization | Advances in Computational Mathematics | 2006 | 73 |
The involvement of non-B DNA structures in gross chromosomal rearrangements | DNA Repair | 2006 | 70 |
Processing: programming for the media arts | AI and Society | 2006 | 70 |
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice | Molecular and Cellular Biology | 2006 | 56 |
Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population | Hormone and Metabolic Research | 2006 | 54 |
Long homopurine*homopyrimidine sequences are characteristic of genes expressed in brain and the pseudoautosomal region | Nucleic Acids Research | 2006 | 52 |
Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma | European Journal of Cancer | 2006 | 46 |
FAS death domain deletions and cellular FADD-like interleukin 1beta converting enzyme inhibitory protein (long) overexpression: alternative mechanisms for deregulating the extrinsic apoptotic pathway in diffuse large B-cell lymphoma subtypes | Clinical Cancer Research | 2006 | 34 |
Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis | European Journal of Human Genetics | 2006 | 30 |
The role of inflammatory bowel disease susceptibility loci in multiple sclerosis and systemic lupus erythematosus | Genes and Immunity | 2006 | 23 |
Target DNA structure plays a critical role in RAG transposition | PLoS Biology | 2006 | 22 |
Sticky DNA: in vivo formation in E. coli and in vitro association of long GAA*TTC tracts to generate two independent supercoiled domains | Journal of Molecular Biology | 2006 | 22 |
Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history | Annals of Oncology | 2006 | 20 |
Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in flanking regions | Journal of Biological Chemistry | 2006 | 20 |
Replication restart: a pathway for (CTG).(CAG) repeat deletion in Escherichia coli | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 2006 | 16 |
DM2 CCTG*CAGG repeats are crossover hotspots that are more prone to expansions than the DM1 CTG*CAG repeats in Escherichia coli | Journal of Molecular Biology | 2006 | 16 |