An integrated map of structural variation in 2,504 human genomes | Nature | 2015 | 1.4K |
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes | Nature Genetics | 2015 | 547 |
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia | Nature | 2015 | 503 |
Safety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer | Journal of Clinical Oncology | 2015 | 398 |
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor | Nature | 2015 | 366 |
Mechanisms of aromatase inhibitor resistance | Nature Reviews Cancer | 2015 | 233 |
Prevalence of Overweight and Obesity in the United States, 2007-2012 | JAMA Internal Medicine | 2015 | 188 |
Patterns and functional implications of rare germline variants across 12 cancer types | Nature Communications | 2015 | 170 |
Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia | Blood | 2015 | 150 |
TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy | Cancer Immunology Research | 2015 | 146 |
Optimizing cancer genome sequencing and analysis | Cell Systems | 2015 | 135 |
Outcomes of transformed follicular lymphoma in the modern era: a report from the National LymphoCare Study (NLCS) | Blood | 2015 | 124 |
The genomic landscape of childhood and adolescent melanoma | Journal of Investigative Dermatology | 2015 | 121 |
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis | Cancer Cell | 2015 | 116 |
Systematic review of falls in older adults with cancer | Journal of Geriatric Oncology | 2015 | 100 |
Breastfeeding and breast cancer risk by receptor status--a systematic review and meta-analysis | Annals of Oncology | 2015 | 95 |
Randomized controlled trial of irinotecan drug-eluting beads with simultaneous FOLFOX and bevacizumab for patients with unresectable colorectal liver-limited metastasis | Cancer | 2015 | 93 |
18F-fluoride PET used for treatment monitoring of systemic cancer therapy: results from the National Oncologic PET Registry | Journal of Nuclear Medicine | 2015 | 72 |
Radiofrequency ablation and vertebral augmentation for palliation of painful spinal metastases | Journal of Neuro-Oncology | 2015 | 71 |
Repeatability of 18F-FDG PET/CT in Advanced Non-Small Cell Lung Cancer: Prospective Assessment in 2 Multicenter Trials | Journal of Nuclear Medicine | 2015 | 69 |
Evaluation of Urine Aquaporin-1 and Perilipin-2 Concentrations as Biomarkers to Screen for Renal Cell Carcinoma: A Prospective Cohort Study | JAMA Oncology | 2015 | 62 |
A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells | Cell Reports | 2015 | 61 |
Genome Modeling System: A Knowledge Management Platform for Genomics | PLoS Computational Biology | 2015 | 59 |
HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor | Journal of the National Comprehensive Cancer Network: JNCCN | 2015 | 57 |
HER2 missense mutations have distinct effects on oncogenic signaling and migration | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 51 |