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Top Articles

#TitleJournalYearCitations
1Microglia: a sensor for pathological events in the CNSTrends in Neurosciences19963,967
2Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): A critical reviewJournal of Psychiatric Research19942,123
3The endogenous cannabinoid system controls extinction of aversive memoriesNature20021,603
4CB1 Cannabinoid Receptors and On-Demand Defense Against ExcitotoxicityScience20031,083
5Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinaseNature Genetics19981,061
6Cytotoxicity of microgliaGlia19931,016
7Microglia: Intrinsic immuneffector cell of the brainBrain Research Reviews1995984
8The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesisJournal of Clinical Investigation2003963
9Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communicationFrontiers in Neuroendocrinology2004918
10Functional plasticity of microglia: A reviewGlia1988916
11Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working GroupMolecular Psychiatry2017852
12Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrainEuropean Journal of Neuroscience1999792
13Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility geneNature Genetics2010638
14Prevalence and risk factors of RLS in an elderly populationNeurology2000626
15Test-retest reliability of the computerized DSM-IV version of the Munich-Composite International Diagnostic Interview (M-CIDI)Social Psychiatry and Psychiatric Epidemiology1998595
16Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disordersNature Neuroscience2018490
17Mutations in the deubiquitinase gene USP8 cause Cushing's diseaseNature Genetics2015450
18Parental Major Depression and the Risk of Depression and Other Mental Disorders in OffspringArchives of General Psychiatry2002423
19Antidepressants recruit new neurons to improve stress response regulationMolecular Psychiatry2011406
20Genome-wide association studies identify four ER negative–specific breast cancer risk lociNature Genetics2013374
21Response of endogenous glial cells to motor neuron degeneration induced by toxic ricinJournal of Comparative Neurology1988361
22Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissueNeuroscience1993341
23Cerebral generators involved in the pathogenesis of the restless legs syndromeAnnals of Neurology1997338
24Central CRH system in depression and anxiety — Evidence from clinical studies with CRH1 receptor antagonistsEuropean Journal of Pharmacology2008333
25Why do people with anxiety disorders become depressed? A prospective‐longitudinal community studyActa Psychiatrica Scandinavica2000325
26Evidence That Psychotic Symptoms Are Prevalent in Disorders of Anxiety and Depression, Impacting on Illness Onset, Risk, and Severity--Implications for Diagnosis and Ultra-High Risk ResearchSchizophrenia Bulletin2012324
27Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosisJournal of Psychiatric Research1999310
28The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellumDevelopment (Cambridge)2003302
29Translocator Protein (18 kD) as Target for Anxiolytics Without Benzodiazepine-Like Side EffectsScience2009299
30Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohnʼs disease and analysis of the IL17F p.His161Arg polymorphism in IBDInflammatory Bowel Diseases2008291
31Behavioral Consequences of Intracerebral Vasopressin and Oxytocin: Focus on Learning and Memory **This paper is dedicated to our friend and scientific teacher Prof. Dr Armin Ermisch (1935–1995).Neuroscience and Biobehavioral Reviews1996276
32Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrainNeuroscience2002275
33Heterodimerization between mineralocorticoid and glucocorticoid receptor: A new principle of glucocorticoid action in the CNSNeuron1994268
34Subtle shifts in the ratio between pro‐ and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fateFASEB Journal2000267
35γ-secretase directly sheds the survival receptor BCMA from plasma cellsNature Communications2015267
36Acute and chronic ethanol treatment changes endorphin levels in brain and pituitaryPsychopharmacology1980264
37PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microgliaJournal of Neurocytology1997264
38Endogenous cannabinoid system as a modulator of food intakeInternational Journal of Obesity2003263
39Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1Journal of Neurochemistry2002261
40Impaired neuroglial activation in interleukin-6 deficient miceJournal of Neurochemistry1997253
41The Neurosteroid Tetrahydroprogesterone Attenuates the Endocrine Response to Stress and Exerts Glucocorticoid-like Effects on Vasopressin Gene Transcription in the Rat HypothalamusNeuropsychopharmacology1996250
42The combined dexamethasone/CRH test as a potential surrogate marker in depressionProgress in Neuro-Psychopharmacology and Biological Psychiatry2005244
43Circuitry for Associative Plasticity in the Amygdala Involves Endocannabinoid SignalingJournal of Neuroscience2004239
44FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping BehaviorBiological Psychiatry2011235
45Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age at onset familiesAnnals of Neurology2002229
46Consensus guidelines on screening for hypopituitarism following traumatic brain injuryBrain Injury2005226
47Heterogeneity of DSM-IV Major Depressive Disorder as a Consequence of Subthreshold BipolarityArchives of General Psychiatry2009225
48Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.Journal of Clinical Investigation1996223
49Circadian rhythm of periodic limb movements and sensory symptoms of restless legs syndromeMovement Disorders1999220
50Genomic and phenotypic insights from an atlas of genetic effects on DNA methylationNature Genetics2021218