Transcriptional regulatory networks in Saccharomyces cerevisiae | Science | 2002 | 2.3K |
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Cell | 2002 | 2.3K |
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning | Nature Medicine | 2002 | 1.9K |
Prediction of plant microRNA targets | Cell | 2002 | 1.8K |
MicroRNAs in plants | Genes and Development | 2002 | 1.6K |
Discovering regulatory and signalling circuits in molecular interaction networks | Bioinformatics | 2002 | 877 |
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration | Nature | 2002 | 843 |
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints | Genes and Development | 2002 | 841 |
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 797 |
Modelling the molecular circuitry of cancer | Nature Reviews Cancer | 2002 | 759 |
Molecular self-assembly of surfactant-like peptides to form nanotubes and nanovesicles | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 711 |
HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors | Cell | 2002 | 657 |
A progression puzzle | Nature | 2002 | 632 |
Chromosomal silencing and localization are mediated by different domains of Xist RNA | Nature Genetics | 2002 | 590 |
Human macrophage activation programs induced by bacterial pathogens | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 560 |
Enumeration of the simian virus 40 early region elements necessary for human cell transformation | Molecular and Cellular Biology | 2002 | 528 |
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy | Cell | 2002 | 491 |
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex | Nature Cell Biology | 2002 | 476 |
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells | Nature Medicine | 2002 | 462 |
Monoclonal mice generated by nuclear transfer from mature B and T donor cells | Nature | 2002 | 434 |
Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory | Diabetes | 2002 | 420 |
Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol | Science | 2002 | 408 |
The mosaic structure of variation in the laboratory mouse genome | Nature | 2002 | 404 |
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 371 |
Small RNAs correspond to centromere heterochromatic repeats | Science | 2002 | 368 |