4.7K(top 5%)
articles
1.1M(top 1%)
citations
2,060(top 3%)
★★ articles
1,056(top 1%)
★★★ articles
9.7(top 1%)
Avg IF
495(top 1%)
H-Index
933(top 1%)
G-Index
641
journals

Most Cited Articles of Whitehead Institute in 2000

TitleJournalYearCitations
Primer3 on the WWW for general users and for biologist programmersMethods in Molecular Biology20008.6K
Role of transforming growth factor beta in human diseaseNew England Journal of Medicine20002.1K
Proteomics to study genes and genomesNature20001.9K
Genome-wide location and function of DNA binding proteinsScience20001.7K
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristicsMolecular and Cellular Biology2000766
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3aProceedings of the National Academy of Sciences of the United States of America2000756
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionProceedings of the National Academy of Sciences of the United States of America2000672
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networksProceedings of the National Academy of Sciences of the United States of America2000468
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiationMolecular Cell2000465
Analysing complex genetic traits with chromosome substitution strainsNature Genetics2000386
Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptorsProceedings of the National Academy of Sciences of the United States of America2000380
DNA methylation in Drosophila melanogasterNature2000377
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouseNature Genetics2000371
Chemical genetics: ligand-based discovery of gene functionNature Reviews Genetics2000356
Essential function of Wnt-4 in mammary gland development downstream of progesterone signalingGenes and Development2000343
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietinNature Immunology2000338
ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORFNature Genetics2000332
A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and matingProceedings of the National Academy of Sciences of the United States of America2000319
Biomedical discovery with DNA arraysCell2000316
Redundant roles for the TFIID and SAGA complexes in global transcriptionNature2000311
Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobeNature Neuroscience2000309
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancersNature Genetics2000309
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosisNature Genetics2000308
One sequence, two ribozymes: implications for the emergence of new ribozyme foldsScience2000296
Interactions between the cellular and humoral immune responses in DrosophilaCurrent Biology2000290