Primer3 on the WWW for general users and for biologist programmers | Methods in Molecular Biology | 2000 | 8.6K |
Role of transforming growth factor beta in human disease | New England Journal of Medicine | 2000 | 2.1K |
Proteomics to study genes and genomes | Nature | 2000 | 1.9K |
Genome-wide location and function of DNA binding proteins | Science | 2000 | 1.7K |
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics | Molecular and Cellular Biology | 2000 | 766 |
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 756 |
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 672 |
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 468 |
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation | Molecular Cell | 2000 | 465 |
Analysing complex genetic traits with chromosome substitution strains | Nature Genetics | 2000 | 386 |
Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 380 |
DNA methylation in Drosophila melanogaster | Nature | 2000 | 377 |
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse | Nature Genetics | 2000 | 371 |
Chemical genetics: ligand-based discovery of gene function | Nature Reviews Genetics | 2000 | 356 |
Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling | Genes and Development | 2000 | 343 |
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin | Nature Immunology | 2000 | 338 |
ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF | Nature Genetics | 2000 | 332 |
A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 319 |
Biomedical discovery with DNA arrays | Cell | 2000 | 316 |
Redundant roles for the TFIID and SAGA complexes in global transcription | Nature | 2000 | 311 |
Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe | Nature Neuroscience | 2000 | 309 |
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers | Nature Genetics | 2000 | 309 |
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis | Nature Genetics | 2000 | 308 |
One sequence, two ribozymes: implications for the emergence of new ribozyme folds | Science | 2000 | 296 |
Interactions between the cellular and humoral immune responses in Drosophila | Current Biology | 2000 | 290 |