| # | Title | Journal | Year | Citations |
|---|
| 1 | Human papillomavirus is a necessary cause of invasive cervical cancer worldwide | Chemistry - A European Journal | 1999 | 7,095 |
| 2 | Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis | Lancet, The | 2006 | 997 |
| 3 | p53 and Human Cancer: The First Ten Thousand Mutations | Advances in Cancer Research | 1999 | 805 |
| 4 | Overweight, obesity, and cancer risk | Lancet Oncology, The | 2002 | 784 |
| 5 | Evidence Regarding Human Papillomavirus Testing in Secondary Prevention of Cervical Cancer | Vaccine | 2012 | 695 |
| 6 | Perinatal mortality and other severe adverse pregnancy outcomes associated with treatment of cervical intraepithelial neoplasia: meta-analysis | BMJ: British Medical Journal | 2008 | 580 |
| 7 | Guidelines for human papillomavirus DNA test requirements for primary cervical cancer screening in women 30 years and older | International Journal of Cancer | 2009 | 557 |
| 8 | Lung cancer susceptibility locus at 5p15.33 | Nature Genetics | 2008 | 514 |
| 9 | The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. | Clinical Cancer Research | 2006 | 495 |
| 10 | Human Papillomavirus Genotype Distribution in Low-Grade Cervical Lesions: Comparison by Geographic Region and with Cervical Cancer | Cancer Epidemiology Biomarkers and Prevention | 2005 | 472 |
| 11 | Activation and Caspase-mediated Inhibition of PARP: A Molecular Switch between Fibroblast Necrosis and Apoptosis in Death Receptor Signaling | Molecular Biology of the Cell | 2002 | 434 |
| 12 | Chapter 9: Clinical applications of HPV testing: A summary of meta-analyses | Vaccine | 2006 | 393 |
| 13 | A strain-based porosity model for use in hydrocode simulations of impacts and implications for transient crater growth in porous targets | Icarus | 2006 | 391 |
| 14 | Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype | Cancer Research | 2003 | 350 |
| 15 | Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin | Nature Medicine | 1999 | 348 |
| 16 | Changing epidemiology of malignant cutaneous melanoma in Europe 1953-1997: Rising trends in incidence and mortality but recent stabilizations in Western Europe and decreases in Scandinavia | International Journal of Cancer | 2003 | 336 |
| 17 | Estimates of Cancer Incidence in China for 2000 and Projections for 2005 | Cancer Epidemiology Biomarkers and Prevention | 2005 | 285 |
| 18 | Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communication | Cancer Research | 2000 | 273 |
| 19 | Screening for liver cancer: results of a randomised controlled trial in Qidong, China | Journal of Medical Screening | 2003 | 261 |
| 20 | European Code Against Cancer and scientific justification: third version (2003) | Annals of Oncology | 2003 | 247 |
| 21 | Identification of failure modes in glass/polypropylene composites by means of the primary frequency content of the acoustic emission event | Composites Science and Technology | 2004 | 243 |
| 22 | TP53 and KRAS Mutation Load and Types in Lung Cancers in Relation to Tobacco Smoke: Distinct Patterns in Never, Former, and Current Smokers | Cancer Research | 2005 | 237 |
| 23 | Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors | Cancer Research | 2009 | 231 |
| 24 | Global Oral Health Inequalities in Incidence and Outcomes for Oral Cancer | Advances in Dental Research | 2011 | 224 |
| 25 | The exposome in practice: Design of the EXPOsOMICS project | International Journal of Hygiene and Environmental Health | 2017 | 219 |
| 26 | Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study | BMJ: British Medical Journal | 2011 | 218 |
| 27 | Diagnostic accuracy of human papillomavirus testing in primary cervical screening: A systematic review and meta-analysis of non-randomized studies | Gynecologic Oncology | 2007 | 217 |
| 28 | Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study | Cancer Epidemiology Biomarkers and Prevention | 2006 | 211 |
| 29 | Classification of rare missense substitutions, using risk surfaces, with genetic- and molecular-epidemiology applications | Human Mutation | 2008 | 209 |
| 30 | Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis | International Journal of Cancer | 2003 | 207 |
| 31 | Testicular Cancer Incidence in Eight Northern European Countries: Secular and Recent Trends | Cancer Epidemiology Biomarkers and Prevention | 2004 | 207 |
| 32 | p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers | Carcinogenesis | 1994 | 198 |
| 33 | Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study | Epigenomics | 2016 | 192 |
| 34 | Genetics of lung-cancer susceptibility | Lancet Oncology, The | 2011 | 191 |
| 35 | Physical Activity and Risk of Colon and Rectal Cancers: The European Prospective Investigation into Cancer and Nutrition | Cancer Epidemiology Biomarkers and Prevention | 2006 | 190 |
| 36 | Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma | British Journal of Cancer | 2008 | 183 |
| 37 | In silico analysis of missense substitutions using sequence-alignment based methods | Human Mutation | 2008 | 181 |
| 38 | Smoking, The Missing Drug Interaction in Clinical Trials: Ignoring the Obvious | Cancer Epidemiology Biomarkers and Prevention | 2005 | 179 |
| 39 | Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies | Clinical Cancer Research | 1997 | 176 |
| 40 | Carcinogenicity of trichloroethylene, tetrachloroethylene, some other chlorinated solvents, and their metabolites | Lancet Oncology, The | 2012 | 167 |
| 41 | Reported family aggregation of pancreatic cancer within a population-based case-control study in the francophone community in Montreal, Canada | International Journal of Gastrointestinal Cancer | 1991 | 158 |
| 42 | TP53 and KRAS2 Mutations in Plasma DNA of Healthy Subjects and Subsequent Cancer Occurrence: A Prospective Study | Cancer Research | 2006 | 158 |
| 43 | Numerical modelling of impact melt production in porous rocks | Earth and Planetary Science Letters | 2008 | 152 |
| 44 | Evidence for an Important Role of Alcohol- and Aldehyde-Metabolizing Genes in Cancers of the Upper Aerodigestive Tract | Cancer Epidemiology Biomarkers and Prevention | 2006 | 148 |
| 45 | A Prospective Study of Growth and Biomarkers of Exposure to Aflatoxin and Fumonisin during Early Childhood in Tanzania | Environmental Health Perspectives | 2015 | 147 |
| 46 | Orchestration of chromatin-based processes: mind the TRRAP | Oncogene | 2007 | 142 |
| 47 | Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein | Cancer Research | 1997 | 141 |
| 48 | Genetic alterations associated with the evolution and progression of astrocytic brain tumours | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 1995 | 130 |
| 49 | Prospect-EPIC Utrecht: study design and characteristics of the cohort population. European Prospective Investigation into Cancer and Nutrition | European Journal of Epidemiology | 2001 | 130 |
| 50 | The viral origin of cervical cancer in Rabat, Morocco | European Journal of Epidemiology | 1998 | 126 |
